Publications by authors named "Sumathy Mathialagan"

Claim this Profile
P
Pyridoxic Acid as Endogenous Biomarker of Renal Organic Anion Transporter Activity: Population Variability and Mechanistic Modeling to Predict Drug-Drug Interactions.
Aarzoo Thakur, Sumathy Mathialagan, Emi Kimoto, Manthena V S Varma

CPT Pharmacometrics Syst Pharmacol· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
.
.
Yi-An Bi, Samantha Jordan, Amanda King-Ahmad, Mark A West, Emi Yamaguchi, Sumathy Mathialagan

Drug Metab Dispos· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Significance of Organic Anion Transporter 2 and Organic Cation Transporter 2 in Creatinine Clearance: Mechanistic Evaluation Using Freshly Prepared Human Primary Renal Proximal Tubule Cells.
Sumathy Mathialagan, Git Chung, Keith Pye, A David Rodrigues, Manthena V S Varma

J Pharmacol Exp Ther· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Utilization of Rosuvastatin and Endogenous Biomarkers in Evaluating the Impact of Ritlecitinib on BCRP, OATP1B1, and OAT3 Transporter Activity.
Yeamin Huh, Anna Plotka, Hua Wei, Julia Kaplan, Nancy Raha, Sumathy Mathialagan

Pharm Res· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of the Impact of Ritlecitinib on Organic Cation Transporters Using Sumatriptan and Biomarkers as Probes.
Xiaoxing Wang, Vivek Purohit, Martin E Dowty, David Rodrigues, Lina Luo, Sumathy Mathialagan

J Clin Pharmacol· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of Bile Acid Sulfate Conjugates as Substrates of Human Organic Anion Transporting Polypeptides.
Christine C Orozco, Mikko Neuvonen, Yi-An Bi, Matthew A Cerny, Sumathy Mathialagan

Mol Pharm· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of Organic Anion Transporter 2 Inhibitors: Screening, Structure-Based Analysis, and Clinical Drug Interaction Risk Assessment.
Sangwoo Ryu, Nathaniel Woody, George Chang, Sumathy Mathialagan, Manthena V S Varma

J Med Chem· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of the Effect of Abrocitinib on Drug Transporters by Integrated Use of Probe Drugs and Endogenous Biomarkers.
Manoli Vourvahis, Wonkyung Byon, Cheng Chang, Vu Le, Annette Diehl, Sumathy Mathialagan

Clin Pharmacol Ther· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
.
.
Yan Weng, Kari R Fonseca, Yi-An Bi, Sumathy Mathialagan, Keith Riccardi

Drug Metab Dispos· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development and implementation of urinary transporter biomarkers to facilitate assessment of drug-drug interaction.
Lina Luo, Manoli Vourvahis, Lauren Horlbogen, Roshan Patel, Sumathy Mathialagan

Bioanalysis· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Drug-Drug Interactions Involving Renal OCT2/MATE Transporters: Clinical Risk Assessment May Require Endogenous Biomarker-Informed Approach.
Sumathy Mathialagan, Bo Feng, A David Rodrigues, Manthena V S Varma

Clin Pharmacol Ther· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of Glycochenodeoxycholate 3-O-Glucuronide and Glycodeoxycholate 3-O-Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers.
Mikko Neuvonen, Päivi Hirvensalo, Aleksi Tornio, Brian Rago, Mark West, Sumathy Mathialagan

Clin Pharmacol Ther· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein-Mediated Drug-Drug Interactions in Healthy Volunteers.
Takeshi Miyake, Emi Kimoto, Lina Luo, Sumathy Mathialagan, Lauren M Horlbogen

Clin Pharmacol Ther· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Multiplexed HILIC-MS/HRMS Assay for the Assessment of Transporter Inhibition Biomarkers in Phase I Clinical Trials: Isobutyryl-Carnitine as an Organic Cation Transporter (OCT1) Biomarker.
Lina Luo, Ragu Ramanathan, Lauren Horlbogen, Sumathy Mathialagan, Chester Costales

Anal Chem· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In Vivo-to-In Vitro Extrapolation of Transporter-Mediated Renal Clearance: Relative Expression Factor Versus Relative Activity Factor Approach.
Aditya R Kumar, Bhagwat Prasad, Deepak Kumar Bhatt, Sumathy Mathialagan, Manthena V S Varma

Drug Metab Dispos· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nicotinic acid transport into human liver involves organic anion transporter 2 (SLC22A7).
Sumathy Mathialagan, Yi-An Bi, Chester Costales, Amit S Kalgutkar, A David Rodrigues

Biochem Pharmacol· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Estimation of the Effect of OAT2-Mediated Active Uptake on Meloxicam Exposure in the Human Liver.
Rui Li, Sumathy Mathialagan, Jonathan J Novak, Heather Eng, Keith Riccardi

AAPS J· January 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effect of Hepatic Organic Anion-Transporting Polypeptide 1B Inhibition and Chronic Kidney Disease on the Pharmacokinetics of a Liver-Targeted Glucokinase Activator: A Model-Based Evaluation.
Arthur Bergman, Yi-An Bi, Sumathy Mathialagan, John Litchfield, David J Kazierad

Clin Pharmacol Ther· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Q
Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: "SLC-Phenotyping" Using Primary Human Hepatocytes.
Yi-An Bi, Chester Costales, Sumathy Mathialagan, Mark West, Soraya Eatemadpour

J Pharmacol Exp Ther· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Organic Anion Transporter 2-Mediated Hepatic Uptake Contributes to the Clearance of High-Permeability-Low-Molecular-Weight Acid and Zwitterion Drugs: Evaluation Using 25 Drugs.
Emi Kimoto, Sumathy Mathialagan, Laurie Tylaska, Mark Niosi, Jian Lin

J Pharmacol Exp Ther· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Human Pluripotent Stem Cell-Derived Kidney Model for Nephrotoxicity Studies.
Piyush Bajaj, A David Rodrigues, Claire M Steppan, Sandra J Engle, Sumathy Mathialagan

Drug Metab Dispos· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro studies with two human organic anion transporters: OAT2 and OAT7.
Sumathy Mathialagan, Chester Costales, Laurie Tylaska, Emi Kimoto, Anna Vildhede

Xenobiotica· October 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug.
Yi-An Bi, Sumathy Mathialagan, Laurie Tylaska, Myra Fu, Julie Keefer

J Pharmacol Exp Ther· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Role of Hepatic Organic Anion Transporter 2 in the Pharmacokinetics of R- and S-Warfarin: In Vitro Studies and Mechanistic Evaluation.
Yi-An Bi, Jian Lin, Sumathy Mathialagan, Laurie Tylaska, Ernesto Callegari

Mol Pharm· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK).
David J Edmonds, Daniel W Kung, Amit S Kalgutkar, Kevin J Filipski, David C Ebner, Sumathy Mathialagan

J Med Chem· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis