Publications by authors named "Sumit Handa"

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RNA control of reverse transcription in a diversity-generating retroelement.
Sumit Handa, Tapan Biswas, Jeet Chakraborty, Gourisankar Ghosh, Blair G Paul

Nature· February 2025

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Structural Requirements for Reverse Transcription by a Diversity-generating Retroelement.
Sumit Handa, Tapan Biswas, Jeet Chakraborty, Gourisankar Ghosh, Blair G Paul

bioRxiv· June 2024

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Structural and biochemical characterization of Lsa45 reveals a penicillin-binding protein with esterase activity.
Jademilson C Santos, Sumit Handa, Luis G V Fernandes, Lucas Bleicher, César A Gandin

Process Biochem· February 2023

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Determinants of adenine-mutagenesis in diversity-generating retroelements.
Sumit Handa, Andres Reyna, Timothy Wiryaman, Partho Ghosh

Nucleic Acids Res· January 2021

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Crystal structure of a Thermus aquaticus diversity-generating retroelement variable protein.
Sumit Handa, Kharissa L Shaw, Partho Ghosh

PLoS One· September 2019

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Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex.
Sumit Handa, Yong Jiang, Sijia Tao, Robert Foreman, Raymond F Schinazi

Nucleic Acids Res· October 2018

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Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey.
Li Wu, Mari Gingery, Michael Abebe, Diego Arambula, Elizabeth Czornyj, Sumit Handa

Nucleic Acids Res· January 2018

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Mechanistic Studies of 1-Deoxy-D-Xylulose-5-Phosphate Synthase from .
Sumit Handa, Daniel R Dempsey, Divya Ramamoorthy, Nanci Cook, Wayne C Guida

Biochem Mol Biol J· January 2018

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Retroelement-guided protein diversification abounds in vast lineages of Bacteria and Archaea.
Blair G Paul, David Burstein, Cindy J Castelle, Sumit Handa, Diego Arambula

Nat Microbiol· April 2017

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Thiamin Diphosphate Activation in 1-Deoxy-d-xylulose 5-Phosphate Synthase: Insights into the Mechanism and Underlying Intermolecular Interactions.
Justin K White, Sumit Handa, Sai Lakshmana Vankayala, David J Merkler, H Lee Woodcock

J Phys Chem B· September 2016

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Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements.
Sumit Handa, Blair G Paul, Jeffery F Miller, David L Valentine, Partho Ghosh

BMC Struct Biol· August 2016

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Mechanistic binding insights for 1-deoxy-D-Xylulose-5-Phosphate synthase, the enzyme catalyzing the first reaction of isoprenoid biosynthesis in the malaria-causing protists, Plasmodium falciparum and Plasmodium vivax.
Matthew R Battistini, Christopher Shoji, Sumit Handa, Leonid Breydo, David J Merkler

Protein Expr Purif· April 2016

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Mechanistic and Structural Analysis of a Drosophila melanogaster Enzyme, Arylalkylamine N-Acetyltransferase Like 7, an Enzyme That Catalyzes the Formation of N-Acetylarylalkylamides and N-Acetylhistamine.
Daniel R Dempsey, Kristen A Jeffries, Sumit Handa, Anne-Marie Carpenter, Santiago Rodriguez-Ospina

Biochemistry· April 2015

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Targeted diversity generation by intraterrestrial archaea and archaeal viruses.
Blair G Paul, Sarah C Bagby, Elizabeth Czornyj, Diego Arambula, Sumit Handa

Nat Commun· March 2015

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Production of recombinant 1-deoxy-d-xylulose-5-phosphate synthase from Plasmodium vivax in Escherichia coli.
Sumit Handa, Divya Ramamoorthy, Tyler J Spradling, Wayne C Guida, John H Adams

FEBS Open Bio· June 2013

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Production of the catalytic core of human peptidylglycine α-hydroxylating monooxygenase (hPHMcc) in Escherichia coli.
Sumit Handa, Tyler J Spradling, Daniel R Dempsey, David J Merkler

Protein Expr Purif· July 2012

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N-acylethanolamines as novel alcohol dehydrogenase 3 substrates.
Milena Ivkovic, Daniel R Dempsey, Sumit Handa, Joshua H Hilton, Edward W Lowe

Arch Biochem Biophys· February 2011

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