Publications by authors named "Surya A Reis"

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Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia.
Zachary C Rosenthal, Daniel M Fass, N Connor Payne, Angela She, Debasis Patnaik, Surya A Reis

Sci Rep· April 2024

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High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy.
Chialin Cheng, Surya A Reis, Emily T Adams, Daniel M Fass, Steven P Angus

Sci Rep· August 2021

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TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling.
Pauline Martin, Vilas Wagh, Surya A Reis, Serkan Erdin, Roberta L Beauchamp

Mol Autism· December 2020

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Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery.
Vadim Bernard-Gauthier, Andrew V Mossine, Ashley Knight, Debasis Patnaik, Wen-Ning Zhao, Surya A Reis

J Med Chem· November 2019

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An Autophagy Modifier Screen Identifies Small Molecules Capable of Reducing Autophagosome Accumulation in a Model of CLN3-Mediated Neurodegeneration.
Anton Petcherski, Uma Chandrachud, Elisabeth S Butz, Madeleine C Klein, Wen-Ning Zhao, Surya A Reis

Cells· November 2019

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A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy.
Israel Hernandez, Gabriel Luna, Jennifer N Rauch, Surya A Reis, Michel Giroux

Sci Transl Med· March 2019

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Disruption of the psychiatric risk gene Ankyrin 3 enhances microtubule dynamics through GSK3/CRMP2 signaling.
Jacob C Garza, Xiaoli Qi, Klaudio Gjeluci, Melanie P Leussis, Himanish Basu, Surya A Reis

Transl Psychiatry· July 2018

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Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability.
Jasmin Lalonde, Surya A Reis, Sudhir Sivakumaran, Carl S Holland, Hendrik Wesseling

Nat Commun· November 2017

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Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia.
Angela She, Iren Kurtser, Surya A Reis, Krista Hennig, Jenny Lai

Cell Chem Biol· July 2017

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Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.
Florence F Wagner, Michel Weïwer, Stefan Steinbacher, Adrian Schomburg, Peter Reinemer, Surya A Reis

Bioorg Med Chem· September 2016

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Light-controlled modulation of gene expression by chemical optoepigenetic probes.
Surya A Reis, Balaram Ghosh, J Adam Hendricks, D Miklos Szantai-Kis, Lisa Törk

Nat Chem Biol· May 2016

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Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation.
Balaram Ghosh, Wen-Ning Zhao, Surya A Reis, Debasis Patnaik, Daniel M Fass

Bioorg Med Chem Lett· February 2016

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Monoalkoxy BODIPYs--a fluorophore class for bioimaging.
Alexandra M Courtis, Sofia A Santos, Yinghua Guan, J Adam Hendricks, Balaram Ghosh, Surya A Reis

Bioconjug Chem· June 2014

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Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.
Daniel M Fass, Surya A Reis, Balaram Ghosh, Krista M Hennig, Nadine F Joseph

Neuropharmacology· January 2013

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Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome.
Steven D Sheridan, Kraig M Theriault, Surya A Reis, Fen Zhou, Jon M Madison

PLoS One· February 2012

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Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.
Surya A Reis, Morgan N Thompson, Jong-Min Lee, Elisa Fossale, Hyung-Hwan Kim

Hum Mol Genet· June 2011

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An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.
Lisa A Marcaurelle, Eamon Comer, Sivaraman Dandapani, Jeremy R Duvall, Baudouin Gerard, Surya A Reis

J Am Chem Soc· December 2010

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Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.
Daniel M Fass, Rishita Shah, Balaram Ghosh, Krista Hennig, Stephanie Norton, Surya A Reis

ACS Med Chem Lett· October 2010

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Isolation of mouse neuritic mRNAs.
Surya A Reis, Ben A Oostra, Rob Willemsen

J Mol Histol· January 2006

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Prospects of TAT-mediated protein therapy for fragile X syndrome.
Surya A Reis, Rob Willemsen, Leontine van Unen, Andre T Hoogeveen, Ben A Oostra

J Mol Histol· May 2004

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