Publications by authors named "Susan Demo"

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Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: a phase 1b/2 clinical trial and correlative analyses.
Courtney D DiNardo, Divij Verma, Natalia Baran, Tushar D Bhagat, Anna Skwarska, Susan Demo

Nat Cancer· October 2024

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Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses.
Marina Konopleva, Courtney DiNardo, Tushar Bhagat, Natalia Baran, Alessia Lodi, Susan Demo

Res Sq· February 2023

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Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer.
Diane M Demas, Susan Demo, Yassi Fallah, Robert Clarke, Kenneth P Nephew

Front Oncol· August 2019

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The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.
Milica Momcilovic, Sean T Bailey, Jason T Lee, Michael C Fishbein, Daniel Braas, Susan Demo

Cancer Cell· May 2018

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Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer.
Milica Momcilovic, Sean T Bailey, Jason T Lee, Michael C Fishbein, Clara Magyar, Susan Demo

Cell Rep· January 2017

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Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Nathalie Jacque, Anne Marie Ronchetti, Clément Larrue, Godelieve Meunier, Rudy Birsen, Susan Demo

Blood· September 2015

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Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan

Mol Cancer Ther· April 2014

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Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity.
Hao Li, Elizabeth L Ponder, Martijn Verdoes, Kristijana H Asbjornsdottir, Edgar Deu, Susan D Demo

Chem Biol· December 2012

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Molecular mechanisms of bortezomib resistant adenocarcinoma cells.
Erika Suzuki, Susan Demo, Edgar Deu, Jonathan Keats, Shirin Arastu-Kapur

PLoS One· May 2012

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Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenstrom macroglobulinemia.
Aldo M Roccaro, Antonio Sacco, Monette Aujay, Hai T Ngo, Abdel Kareem Azab, Susan Demo

Blood· May 2010

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A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis.
Tony Muchamuel, Michael Basler, Monette A Aujay, Erika Suzuki, Khalid W Kalim, Susan D Demo

Nat Med· July 2009

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Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047).
Han-Jie Zhou, Monette A Aujay, Mark K Bennett, Maya Dajee, Susan D Demo

J Med Chem· May 2009

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Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma.
Deborah J Kuhn, Qing Chen, Peter M Voorhees, John S Strader, Kevin D Shenk, Susan D Demo

Blood· November 2007

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Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome.
Susan D Demo, Christopher J Kirk, Monette A Aujay, Tonia J Buchholz, Maya Dajee

Cancer Res· July 2007

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Cellular localization and antiproliferative effect of peptides discovered from a functional screen of a retrovirally delivered random peptide library.
Yasumichi Hitoshi, Tarikere Gururaja, Denise M Pearsall, Wayne Lang, Poonam Sharma, Susan Demo

Chem Biol· October 2003

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Drug discovery in the ubiquitin regulatory pathway.
Brian R Wong, Francesco Parlati, Kunbin Qu, Susan Demo, Todd Pray

Drug Discov Today· August 2003

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Cell cycle regulatory E3 ubiquitin ligases as anticancer targets.
Todd R Pray, Francesco Parlati, Jianing Huang, Brian R Wong, Donald G Payan, Susan D Demo

Drug Resist Updat· December 2002

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