Publications by authors named "Susan M Schlenner"

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The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program.
Oliver T Burton, Orian Bricard, Samar Tareen, Vaclav Gergelits, Simon Andrews, Susan M Schlenner

Immunity· July 2024

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Targeting conserved TIM3VISTA tumor-associated macrophages overcomes resistance to cancer immunotherapy.
Isaure Vanmeerbeek, Stefan Naulaerts, Jenny Sprooten, Raquel S Laureano, Jannes Govaerts, Susan M Schlenner

Sci Adv· July 2024

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"IL-2 immunotherapy for targeting regulatory T cells in autoimmunity".
Valentina Lykhopiy, Vanshika Malviya, Stephanie Humblet-Baron, Susan M Schlenner

Genes Immun· October 2023

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Regulatory T-cell stability and functional plasticity in health and disease.
Vanshika Malviya, Lidia Yshii, Steffie Junius, Abhishek D Garg, Stephanie Humblet-Baron, Susan M Schlenner

Immunol Cell Biol· February 2023

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Unstable regulatory T cells, enriched for naïve and Nrp1 cells, are purged after fate challenge.
Steffie Junius, Adamantios V Mavrogiannis, Pierre Lemaitre, Margaux Gerbaux, Frederik Staels, Susan M Schlenner

Sci Immunol· July 2021

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A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease.
Lies Van Horebeek, Kelly Hilven, Klara Mallants, Annemarie Van Nieuwenhuijze, Tiina Kelkka, Susan M Schlenner

Hum Mol Genet· April 2019

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Abnormal differentiation of B cells and megakaryocytes in patients with Roifman syndrome.
Jessica Heremans, Josselyn E Garcia-Perez, Ernest Turro, Susan M Schlenner, Ingele Casteels

J Allergy Clin Immunol· August 2018

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Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice.
Annemarie van Nieuwenhuijze, James Dooley, Stéphanie Humblet-Baron, Jayasree Sreenivasan, Marije Koenders, Susan M Schlenner

Cell Mol Life Sci· June 2017

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Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes.
James Dooley, Lei Tian, Susann Schonefeldt, Viviane Delghingaro-Augusto, Josselyn E Garcia-Perez, Susan M Schlenner

Nat Genet· May 2016

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The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity.
James Dooley, Josselyn E Garcia-Perez, Jayasree Sreenivasan, Susan M Schlenner, Roman Vangoitsenhoven

Diabetes· January 2016

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Premature thymic involution is independent of structural plasticity of the thymic stroma.
Dean Franckaert, Susan M Schlenner, Nathalie Heirman, Jason Gill, Gabriel Skogberg

Eur J Immunol· May 2015

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Regulatory T cell differentiation: cooperation saves the day.
Adrian Liston, Susan M Schlenner

EMBO J· May 2015

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Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3⁺ and Foxp3⁻ T cells.
Dean Franckaert, James Dooley, Evelyne Roos, Stefan Floess, Jochen Huehn, Susan M Schlenner

Immunol Cell Biol· April 2015

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Fundamental properties of unperturbed haematopoiesis from stem cells in vivo.
Katrin Busch, Kay Klapproth, Melania Barile, Michael Flossdorf, Tim Holland-Letz, Susan M Schlenner

Nature· February 2015

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The thymic microenvironment differentially regulates development and trafficking of invariant NKT cell sublineages.
Michael B Drennan, Srinath Govindarajan, Katelijne De Wilde, Susan M Schlenner, Carl Ware

J Immunol· December 2014

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A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T-cell receptor signalling.
Bénédicte Cauwe, Lei Tian, Dean Franckaert, Wim Pierson, Kim A Staats, Susan M Schlenner

Immunology· March 2014

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Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation.
Ananya Roy, Goutham Ganesh, Helena Sippola, Sara Bolin, Osama Sawesi, Susan M Schlenner

J Biol Chem· January 2014

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Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.
Wim Pierson, Bénédicte Cauwe, Antonia Policheni, Susan M Schlenner, Dean Franckaert

Nat Immunol· September 2013

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Mast cells limit extracellular levels of IL-13 via a serglycin proteoglycan-serine protease axis.
Ida Waern, Iulia Karlsson, Michael Thorpe, Susan M Schlenner, Thorsten B Feyerabend

Biol Chem· December 2012

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Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut.
Susan M Schlenner, Benno Weigmann, Qingguo Ruan, Youhai Chen, Harald von Boehmer

J Exp Med· August 2012

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Thymus-autonomous T cell development in the absence of progenitor import.
Vera C Martins, Eliana Ruggiero, Susan M Schlenner, Vikas Madan, Manfred Schmidt

J Exp Med· July 2012

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Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice.
Mitsuteru Akahoshi, Chang Ho Song, Adrian M Piliponsky, Martin Metz, Andrew Guzzetta, Susan M Schlenner

J Clin Invest· October 2011

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A role for serglycin proteoglycan in mast cell apoptosis induced by a secretory granule-mediated pathway.
Fabio Rabelo Melo, Ida Waern, Elin Rönnberg, Magnus Åbrink, David M Lee, Susan M Schlenner

J Biol Chem· February 2011

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The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.
George Younan, Freeman Suber, Wei Xing, Tong Shi, Yuichi Kunori, Susan M Schlenner

J Immunol· December 2010

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Early T cell development and the pitfalls of potential.
Susan M Schlenner, Hans-Reimer Rodewald

Trends Immunol· August 2010

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