Publications by authors named "Susan Meakin"

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Brain pH Measurement Using AACID CEST MRI Incorporating the 2 ppm Amine Resonance.
Mohammed Albatany, Susan Meakin, Robert Bartha

Tomography· March 2022

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Brain tumor acidification using drugs simultaneously targeting multiple pH regulatory mechanisms.
Mohammed Albatany, Valeriy G Ostapchenko, Susan Meakin, Robert Bartha

J Neurooncol· September 2019

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The Monocarboxylate transporter inhibitor Quercetin induces intracellular acidification in a mouse model of Glioblastoma Multiforme: in-vivo detection using magnetic resonance imaging.
Mohammed Albatany, Susan Meakin, Robert Bartha

Invest New Drugs· August 2019

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TrkB Regulates N-Methyl-D-Aspartate Receptor Signaling by Uncoupling and Recruiting the Brain-Specific Guanine Nucleotide Exchange Factor, RasGrf1.
Asghar Talebian, Kim Robinson-Brookes, Susan O Meakin

J Mol Neurosci· January 2019

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In vivo detection of acute intracellular acidification in glioblastoma multiforme following a single dose of cariporide.
Mohammed Albatany, Alex Li, Susan Meakin, Robert Bartha

Int J Clin Oncol· October 2018

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Dichloroacetate induced intracellular acidification in glioblastoma: in vivo detection using AACID-CEST MRI at 9.4 Tesla.
Mohammed Albatany, Alex Li, Susan Meakin, Robert Bartha

J Neurooncol· January 2018

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Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.
Melanie K B Wills, Ava Keyvani Chahi, Hayley R Lau, Manali Tilak, Brianna D Guild, Susan O Meakin

J Biol Chem· April 2017

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Topiramate induces acute intracellular acidification in glioblastoma.
Kamini Marathe, Nevin McVicar, Alex Li, Miranda Bellyou, Susan Meakin

J Neurooncol· December 2016

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Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells.
Chunhui Li, James I S MacDonald, Asghar Talebian, Jennifer Leuenberger, Claudia Seah, Susan O Meakin

Mol Cell Biol· October 2016

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Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes.
Weihao Tang, Joshua H K Tam, Claudia Seah, Justin Chiu, Andrea Tyrer, Susan O Meakin

Mol Brain· July 2015

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Imaging chemical exchange saturation transfer (CEST) effects following tumor-selective acidification using lonidamine.
Nevin McVicar, Alex X Li, Susan O Meakin, Robert Bartha

NMR Biomed· May 2015

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The signaling adapter, FRS2, facilitates neuronal branching in primary cortical neurons via both Grb2- and Shp2-dependent mechanisms.
Li Zhou, Asghar Talebian, Susan O Meakin

J Mol Neurosci· March 2015

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Quantitative tissue pH measurement during cerebral ischemia using amine and amide concentration-independent detection (AACID) with MRI.
Nevin McVicar, Alex X Li, Daniela F Gonçalves, Miranda Bellyou, Susan O Meakin

J Cereb Blood Flow Metab· April 2014

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Nerve growth factor receptor TrkA, a new receptor in insulin signaling pathway in PC12 cells.
Thangiah Geetha, Shraddha D Rege, Salome E Mathews, Susan O Meakin, Morris F White

J Biol Chem· August 2013

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Ras guanine nucleotide releasing factor 1 (RasGrf1) enhancement of Trk receptor-mediated neurite outgrowth requires activation of both H-Ras and Rac.
Asghar Talebian, Kim Robinson-Brookes, James I S MacDonald, Susan O Meakin

J Mol Neurosci· January 2013

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Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons.
James I S MacDonald, Alfonso Dietrich, Sarah Gamble, Todd Hryciw, Robert Ian Grant, Susan O Meakin

J Neurochem· June 2012

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Role and expression of FRS2 and FRS3 in prostate cancer.
Tania Valencia, Ajay Joseph, Naveen Kachroo, Steve Darby, Susan Meakin

BMC Cancer· November 2011

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In vivo detection of MRI-PARACEST agents in mouse brain tumors at 9.4 T.
Alex X Li, Mojmir Suchy, Chunhui Li, Joseph S Gati, Susan Meakin

Magn Reson Med· July 2011

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Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells.
Chunhui Li, James I S Macdonald, Todd Hryciw, Susan O Meakin

J Neurochem· February 2010

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The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons.
Todd Hryciw, James I S MacDonald, Renée Phillips, Claudia Seah, Stephen Pasternak, Susan O Meakin

J Neurochem· February 2010

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Trypanosome trans-sialidase mediates neuroprotection against oxidative stress, serum/glucose deprivation, and hypoxia-induced neurite retraction in Trk-expressing PC12 cells.
Alicja Woronowicz, Schammim Ray Amith, Vanessa W Davis, Preethi Jayanth, Kristof De Vusser, Susan O Meakin

Glycobiology· July 2007

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Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3.
Scott J Dixon, James I S MacDonald, Kim N Robinson, Christopher J Kubu, Susan O Meakin

Biochim Biophys Acta· April 2006

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Nerve growth factor increases connexin43 phosphorylation and gap junctional intercellular communication.
Paul Cushing, Ruchi Bhalla, Andrew M Johnson, Walter J Rushlow, Susan O Meakin

J Neurosci Res· December 2005

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Human tumorous imaginal disc 1 (TID1) associates with Trk receptor tyrosine kinases and regulates neurite outgrowth in nnr5-TrkA cells.
Hui-Yu Liu, James I S MacDonald, Todd Hryciw, Chunhui Li, Susan O Meakin

J Biol Chem· May 2005

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Neurotrophin-dependent tyrosine phosphorylation of Ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the HIKE domain of TrkA.
Kim N Robinson, Kara Manto, Rachel J Buchsbaum, James I S MacDonald, Susan O Meakin

J Biol Chem· January 2005

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