Publications by authors named "Susan Moody"

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Improving access to outpatient computed tomography.
Denes Szekeres, Michael Lechner, Susan Moody, Melody Musso, Eric Weinberg

Curr Probl Diagn Radiol· April 2025

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A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer.
Veronica Rendo, Michael Schubert, Nicholas Khuu, Maria F Suarez Peredo Rodriguez, Declan Whyte, Susan Moody

Nat Commun· January 2025

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CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors.
Jiawan Wang, Ana Calizo, Lindy Zhang, James C Pino, Yang Lyu, Susan E Moody

Sci Adv· November 2023

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CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors.
Jiawan Wang, Ana Calizo, Lindy Zhang, James C Pino, Yang Lyu, Susan E Moody

bioRxiv· February 2023

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Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours.
Jordi Rodon, Guillem Argilés, Roisin M Connolly, Ulka Vaishampayan, Maja de Jonge, Susan E Moody

Br J Cancer· July 2021

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Cellular dormancy in minimal residual disease following targeted therapy.
Jason R Ruth, Dhruv K Pant, Tien-Chi Pan, Hans E Seidel, Sanjeethan C Baksh, Susan E Moody

Breast Cancer Res· June 2021

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Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling.
Chen Liu, Hengyu Lu, Hongyun Wang, Alice Loo, Xiamei Zhang, Susan E Moody

Clin Cancer Res· January 2021

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Safety and efficacy of nazartinib (EGF816) in adults with EGFR-mutant non-small-cell lung carcinoma: a multicentre, open-label, phase 1 study.
Daniel S-W Tan, Natasha B Leighl, Gregory J Riely, James C-H Yang, Lecia V Sequist, Susan E Moody

Lancet Respir Med· June 2020

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Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers.
Huai-Xiang Hao, Hongyun Wang, Chen Liu, Steven Kovats, Roberto Velazquez, Susan Moody

Mol Cancer Ther· December 2019

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SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors.
Hengyu Lu, Chen Liu, Roberto Velazquez, Hongyun Wang, Lukas Manuel Dunkl, Susan E Moody

Mol Cancer Ther· July 2019

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Heterogeneity and Coexistence of T790M and T790 Wild-Type Resistant Subclones Drive Mixed Response to Third-Generation Epidermal Growth Factor Receptor Inhibitors in Lung Cancer.
Zofia Piotrowska, Mehlika Hazar-Rethinam, Coleen Rizzo, Brandon Nadres, Emily E Van Seventer, Susan Moody

JCO Precis Oncol· July 2018

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SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors.
Leila Dardaei, Hui Qin Wang, Manrose Singh, Paul Fordjour, Katherine X Shaw, Susan Moody

Nat Med· May 2018

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mutant tumors depend on oxoglutarate dehydrogenase.
Nina Ilic, Kıvanç Birsoy, Andrew J Aguirre, Nora Kory, Michael E Pacold, Susan E Moody

Proc Natl Acad Sci U S A· April 2017

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Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.
Zehua Zhu, Amir R Aref, Travis J Cohoon, Thanh U Barbie, Yu Imamura, Susan E Moody

Cancer Discov· April 2014

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Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers.
Maria B Raeder, Even Birkeland, Jone Trovik, Camilla Krakstad, Shyemaa Shehata, Susan E Moody

PLoS One· August 2013

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Functional genomics and cancer drug target discovery.
Susan E Moody, Jesse S Boehm, David A Barbie, William C Hahn

Curr Opin Mol Ther· June 2010

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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
David A Barbie, Pablo Tamayo, Jesse S Boehm, So Young Kim, Susan E Moody

Nature· November 2009

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Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss.
Michael T Debies, Shelley A Gestl, Jessica L Mathers, Oliver R Mikse, Travis L Leonard, Susan E Moody

J Clin Invest· January 2008

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Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.
Christopher J Sarkisian, Blaine A Keister, Douglas B Stairs, Robert B Boxer, Susan E Moody

Nat Cell Biol· May 2007

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Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy.
Collin M Blakely, Alexander J Stoddard, George K Belka, Katherine D Dugan, Kathleen L Notarfrancesco, Susan E Moody

Cancer Res· June 2006

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Induction of neuregulin signaling in mouse schwann cells in vivo mimics responses to denervation.
Christopher R Hayworth, Susan E Moody, Lewis A Chodosh, Paul Krieg, Mendell Rimer

J Neurosci· June 2006

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Defective neuromuscular synaptogenesis in mice expressing constitutively active ErbB2 in skeletal muscle fibers.
Olga N Ponomareva, Hualong Ma, Vita M Vock, Elaine L Ellerton, Susan E Moody

Mol Cell Neurosci· February 2006

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The transcriptional repressor Snail promotes mammary tumor recurrence.
Susan E Moody, Denise Perez, Tien-chi Pan, Christopher J Sarkisian, Carla P Portocarrero

Cancer Cell· September 2005

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Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors.
Rebecca S Muraoka-Cook, Hirokazu Kurokawa, Yasuhiro Koh, James T Forbes, L Renee Roebuck, Susan E Moody

Cancer Res· December 2004

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Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis.
Edward J Gunther, Susan E Moody, George K Belka, Kristina T Hahn, Nathalie Innocent

Genes Dev· February 2003

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