Publications by authors named "Susan Summerhill"

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Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties.
Olivier René, Benjamin P Fauber, Adrian Barnard, Kerry Chapman, Yuzhong Deng, Susan Summerhill

Bioorg Med Chem Lett· September 2016

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Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists.
Benjamin P Fauber, Alberto Gobbi, Kirk Robarge, Aihe Zhou, Adrian Barnard, Susan Summerhill

Bioorg Med Chem Lett· August 2015

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Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist.
Benjamin P Fauber, Olivier René, Yuzhong Deng, Jason DeVoss, Céline Eidenschenk, Susan Summerhill

J Med Chem· July 2015

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LPS challenge in healthy subjects: an investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2.
Raminder Aul, Sheena Patel, Susan Summerhill, Iain Kilty, Jonathan Plumb

Int Immunopharmacol· July 2012

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Efficient conversion of a nonselective norepinephrin reuptake inhibitor into a dual muscarinic antagonist-β₂-agonist for the treatment of chronic obstructive pulmonary disease.
Rachel Osborne, Nick Clarke, Paul Glossop, Amy Kenyon, Hao Liu, Susan Summerhill

J Med Chem· October 2011

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A cell-based assay to assess the persistence of action of agonists acting at recombinant human beta(2) adrenoceptors.
Susan Summerhill, Timothy Stroud, Roshini Nagendra, Christelle Perros-Huguet, Michael Trevethick

J Pharmacol Toxicol Methods· February 2009

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