Publications by authors named "Susan Swain"

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Oncological and functional outcomes for transoral robotic surgery versus radiotherapy in T1-2 N0-1 p16+ oropharyngeal carcinoma.
Chang Woo Lee, Wei Jia, Roanna Norman, Alex Dando, Susan Swain

J Laryngol Otol· August 2025

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CD4 memory has a hierarchical structure created by requirements for infection-derived signals at an effector checkpoint.
Susan L Swain

Front Immunol· December 2023

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Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15.
Priyadharshini Devarajan, Allen M Vong, Catherine H Castonguay, Noah J Silverstein, Olivia Kugler-Umana, Susan L Swain

Cell Rep· November 2023

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Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15.
Priyadharshini Devarajan, Allen M Vong, Catherine H Castonguay, Noah J Silverstein, Olivia Kugler-Umana, Susan L Swain

Cell Rep· October 2023

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CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated.
Michael C Jones, Catherine Castonguay, Padma P Nanaware, Grant C Weaver, Brian Stadinski, Susan L Swain

J Immunol· June 2023

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IgD age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged.
Olivia Kugler-Umana, Wenliang Zhang, Yi Kuang, Jialing Liang, Catherine H Castonguay, Susan L Swain

Aging Cell· October 2022

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Bona Fide Th17 Cells without Th1 Functional Plasticity Protect against Influenza.
Kunal Dhume, Caroline M Finn, Priyadharshini Devarajan, Ayushi Singh, Joanne D Tejero, Susan L Swain

J Immunol· April 2022

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Strong influenza-induced T generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection.
Priyadharshini Devarajan, Allen M Vong, Catherine H Castonguay, Olivia Kugler-Umana, Bianca L Bautista, Susan L Swain

Proc Natl Acad Sci U S A· February 2022

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Durable CD4 T-Cell Memory Generation Depends on Persistence of High Levels of Infection at an Effector Checkpoint that Determines Multiple Fates.
Susan L Swain, Michael C Jones, Priyadharshini Devarajan, Jingya Xia, Richard W Dutton

Cold Spring Harb Perspect Biol· November 2021

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Understanding the Heterogeneous Population of Age-Associated B Cells and Their Contributions to Autoimmunity and Immune Response to Pathogens.
Olivia Kugler-Umana, Priyadharshini Devarajan, Susan L Swain

Crit Rev Immunol· October 2021

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"An Intrinsic Program Determines Key Age-Associated Changes in Adaptive Immunity that Limit Response to Non-Pathogens.".
Susan L Swain, Olivia Kugler-Umana, Susan Tonkonogy

Front Aging· June 2021

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Influenza Vaccine-Induced CD4 Effectors Require Antigen Recognition at an Effector Checkpoint to Generate CD4 Lung Memory and Antibody Production.
Jingya Xia, Yi Kuang, Jialing Liang, Michael Jones, Susan L Swain

J Immunol· October 2020

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CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation.
Fahmida Alam, Ayushi Singh, Valeria Flores-Malavet, Stewart Sell, Andrea M Cooper, Susan L Swain

J Immunol· June 2020

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Virus-induced natural killer cell lysis of T cell subsets.
Keith A Daniels, Carey L O'Donnell, Catherine Castonguay, Tara M Strutt, K Kai McKinstry, Susan L Swain

Virology· January 2020

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Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation.
K Kai McKinstry, Fahmida Alam, Valeria Flores-Malavet, Mate Z Nagy, Stewart Sell, Susan L Swain

PLoS Pathog· August 2019

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Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus.
Priyadharshini Devarajan, Michael C Jones, Olivia Kugler-Umana, Allen M Vong, Jingya Xia, Susan L Swain

Front Immunol· May 2019

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Original Antigenic Sin: Friend or Foe in Developing a Broadly Cross-Reactive Vaccine to Influenza?
Priyadharshini Devarajan, Susan L Swain

Cell Host Microbe· March 2019

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The properties of the unique age-associated B cell subset reveal a shift in strategy of immune response with age.
Susan L Swain, Olivia Kugler-Umana, Yi Kuang, Wenliang Zhang

Cell Immunol· November 2017

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IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo.
Vinayak Brahmakshatriya, Yi Kuang, Priyadharshini Devarajan, Jingya Xia, Wenliang Zhang, Susan L Swain

J Immunol· April 2017

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NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection.
Nikki B Marshall, Allen M Vong, Priyadharshini Devarajan, Matthew D Brauner, Yi Kuang, Susan L Swain

J Immunol· February 2017

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Short-Lived Antigen Recognition but Not Viral Infection at a Defined Checkpoint Programs Effector CD4 T Cells To Become Protective Memory.
Bianca L Bautista, Priyadharshini Devarajan, K Kai McKinstry, Tara M Strutt, Allen M Vong, Susan L Swain

J Immunol· November 2016

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Direct IL-6 Signals Maximize Protective Secondary CD4 T Cell Responses against Influenza.
Tara M Strutt, Karl Kai McKinstry, Yi Kuang, Caroline M Finn, Ji Hae Hwang, Susan L Swain

J Immunol· October 2016

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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.
Roberto Tinoco, Florent Carrette, Monique L Barraza, Dennis C Otero, Jonathan Magaña, Susan L Swain

Immunity· June 2016

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IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans.
Xin Zhou, Jacob W Hopkins, Chongkai Wang, Vinayak Brahmakshatriya, Susan L Swain

Oncotarget· June 2016

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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.
Roberto Tinoco, Florent Carrette, Monique L Barraza, Dennis C Otero, Jonathan Magaña, Susan L Swain

Immunity· May 2016

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