Publications by authors named "Susanne B Breitkopf"

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Author Correction: An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
Ming Chen, Jiangwen Zhang, Katia Sampieri, John G Clohessy, Lourdes Mendez, Susanne B Breitkopf

Nat Genet· November 2025

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Discovery of Selective and Orally Bioavailable Heterobifunctional Degraders of Cyclin-Dependent Kinase 2.
Philip N Collier, Xiaozhang Zheng, Melissa Ford, Matthew Weiss, Dapeng Chen, Susanne B Breitkopf

J Med Chem· September 2025

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KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors.
Yogesh K Chutake, Michele F Mayo, Nancy Dumont, Jessica Filiatrault, Susanne B Breitkopf

Mol Cancer Ther· April 2025

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CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers.
Nicholas Kwiatkowski, Tong Liang, Zhe Sha, Philip N Collier, Annan Yang, Susanne B Breitkopf

Cell Chem Biol· April 2025

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Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.
Rachel J Roth Flach, Eliza Bollinger, Allan R Reyes, Brigitte Laforest, Bethany L Kormos, Susanne B Breitkopf

Nat Commun· August 2023

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Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity.
Stephen E Flaherty, Olivier Bezy, Wei Zheng, Dong Yan, Xiangping Li, Susanne B Breitkopf

Nat Commun· July 2023

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Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC-MS/MS.
Min Yuan, Daniel M Kremer, He Huang, Susanne B Breitkopf, Issam Ben-Sahra

Nat Protoc· February 2019

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An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
Ming Chen, Jiangwen Zhang, Katia Sampieri, John G Clohessy, Lourdes Mendez, Susanne B Breitkopf

Nat Genet· February 2018

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Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.
John A Bowden, Alan Heckert, Candice Z Ulmer, Christina M Jones, Jeremy P Koelmel, Susanne B Breitkopf

J Lipid Res· December 2017

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Serial-omics of P53-/-, Brca1-/- Mouse Breast Tumor and Normal Mammary Gland.
Susanne B Breitkopf, Mateus De Oliveira Taveira, Min Yuan, Gerburg M Wulf, John M Asara

Sci Rep· November 2017

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Serial-omics characterization of equine urine.
Min Yuan, Susanne B Breitkopf, John M Asara

PLoS One· October 2017

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A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source.
Susanne B Breitkopf, Stéphane J H Ricoult, Min Yuan, Ying Xu, David A Peake

Metabolomics· March 2017

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A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.
Susanne B Breitkopf, Xuemei Yang, Michael J Begley, Meghana Kulkarni, Yu-Hsin Chiu

Sci Rep· February 2016

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Triomics Analysis of Imatinib-Treated Myeloma Cells Connects Kinase Inhibition to RNA Processing and Decreased Lipid Biosynthesis.
Susanne B Breitkopf, Min Yuan, Katja P Helenius, Costas A Lyssiotis, John M Asara

Anal Chem· November 2015

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A secreted tyrosine kinase acts in the extracellular environment.
Mattia R Bordoli, Jina Yum, Susanne B Breitkopf, Jonathan N Thon, Joseph E Italiano

Cell· August 2014

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Characterization and analysis of the composition and dynamics of the mammalian riboproteome.
Markus Reschke, John G Clohessy, Nina Seitzer, Daniel P Goldstein, Susanne B Breitkopf

Cell Rep· September 2013

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Reply to MacLeod et al.: Multiple myeloma plasma cells have chameleon characteristics.
Susanne B Breitkopf, Min Yuan, German A Pihan, John M Asara

Proc Natl Acad Sci U S A· January 2013

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Detection of a rare BCR-ABL tyrosine kinase fusion protein in H929 multiple myeloma cells using immunoprecipitation (IP)-tandem mass spectrometry (MS/MS).
Susanne B Breitkopf, Min Yuan, German A Pihan, John M Asara

Proc Natl Acad Sci U S A· October 2012

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Determining in vivo phosphorylation sites using mass spectrometry.
Susanne B Breitkopf, John M Asara

Curr Protoc Mol Biol· April 2012

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A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue.
Min Yuan, Susanne B Breitkopf, Xuemei Yang, John M Asara

Nat Protoc· April 2012

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Metabolomic profiling from formalin-fixed, paraffin-embedded tumor tissue using targeted LC/MS/MS: application in sarcoma.
Andrew D Kelly, Susanne B Breitkopf, Min Yuan, Jeffrey Goldsmith, Dimitrios Spentzos

PLoS One· January 2012

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Proteomics analysis of cellular imatinib targets and their candidate downstream effectors.
Susanne B Breitkopf, Felix S Oppermann, Gyorgy Keri, Markus Grammel, Henrik Daub

J Proteome Res· November 2010

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Quantitative analysis of kinase-proximal signaling in lipopolysaccharide-induced innate immune response.
Kirti Sharma, Chanchal Kumar, György Kéri, Susanne B Breitkopf, Felix S Oppermann

J Proteome Res· May 2010

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Quantitative phosphoproteomics--an emerging key technology in signal-transduction research.
Thiemo B Schreiber, Nina Mäusbacher, Susanne B Breitkopf, Kathrin Grundner-Culemann, Henrik Daub

Proteomics· November 2008

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