Publications by authors named "Suzanne L Mathieu"

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Small molecule interleukin (IL) 17A/A antagonists and antibodies blocking both IL17A/A and IL17A/F demonstrate equivalent degrees of efficacy in preclinical models of skin and joint inflammation.
Eric R Goedken, Zhi Su, Alex Lipovsky, Arun Kannan, Katharine L Chu, Suzanne L Mathieu

J Pharmacol Exp Ther· April 2025

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Therapeutic JAK1 Inhibition Reverses Lupus Nephritis in a Mouse Model and Demonstrates Transcriptional Changes Consistent With Human Disease.
Rachel E Twomey, Stuart J Perper, Susan V Westmoreland, Swetha Srinivasan, Suzanne L Mathieu

ACR Open Rheumatol· December 2024

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Anti-TNF Thioester Glucocorticoid Antibody-Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model.
Christopher C Marvin, Adrian D Hobson, Michael J McPherson, Martin E Hayes, Meena V Patel, Suzanne L Mathieu

J Med Chem· June 2024

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Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC).
Adrian D Hobson, Jianwen Xu, Dennie S Welch, Christopher C Marvin, Michael J McPherson, Suzanne L Mathieu

J Med Chem· September 2023

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Optimization of Drug-Linker to Enable Long-term Storage of Antibody-Drug Conjugate for Subcutaneous Dosing.
Adrian D Hobson, Jianwen Xu, Christopher C Marvin, Michael J McPherson, Markus Hollmann, Suzanne L Mathieu

J Med Chem· July 2023

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Correction to "Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate".
Adrian D Hobson, Michael J McPherson, Martin E Hayes, Christian Goess, Xiang Li, Suzanne L Mathieu

J Med Chem· April 2023

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Correction to "Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads".
Adrian D Hobson, Michael J McPherson, Wendy Waegell, Christian A Goess, Robert H Stoffel, Suzanne L Mathieu

J Med Chem· April 2023

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Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate.
Adrian D Hobson, Michael J McPherson, Martin E Hayes, Christian Goess, Xiang Li, Suzanne L Mathieu

J Med Chem· December 2022

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Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads.
Adrian D Hobson, Michael J McPherson, Wendy Waegell, Christian A Goess, Robert H Stoffel, Suzanne L Mathieu

J Med Chem· March 2022

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Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists.
Jinhe Li, Suzanne L Mathieu, Richard Harris, Jianguo Ji, David J Anderson

J Neuroimmunol· October 2011

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