Publications by authors named "Sven Lindemann"

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Open Source Repurposing Reveals Broad-Spectrum Antiviral Activity of Diphenylureas.
Ulrich A K Betz, Robert Garces, Norbert Beier, Sven Lindemann, Karen C Wolff

Viruses· March 2025

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Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development.
Monique Evelyn Ueberall, Martina Berchthold, Cécile Häberli, Sven Lindemann, Thomas Spangenberg

Parasit Vectors· February 2025

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Translational pharmacokinetic and pharmacodynamic modelling of the anti-ADAMTS-5 NANOBODY (M6495) using the neo-epitope ARGS as a biomarker.
Joao N S Pereira, Ingrid Ottevaere, Benedikte Serruys, Hans Guehring, Christoph Ladel, Sven Lindemann

J Pharmacokinet Pharmacodyn· December 2024

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Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals.
Francisco Castillo, David Ramírez, María C Ramos, Blanca Martinez-Arribas, Elisabeth Domingo-Contreras, Sven Lindemann

Front Pharmacol· July 2024

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Target 2035 - an update on private sector contributions.
Suzanne Ackloo, Albert A Antolin, Jose Manuel Bartolome, Hartmut Beck, Alex Bullock, Sven Lindemann

RSC Med Chem· June 2023

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Target 2035 - update on the quest for a probe for every protein.
Susanne Müller, Suzanne Ackloo, Arij Al Chawaf, Bissan Al-Lazikani, Albert Antolin, Sven Lindemann

RSC Med Chem· January 2022

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A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis.
Solveig Skovlund Groen, Dovile Sinkeviciute, Anne-Christine Bay-Jensen, Christian S Thudium, Morten A Karsdal, Sven Lindemann

Osteoarthr Cartil Open· December 2021

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Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species.
Anne Gigout, Donata Harazin, Louise M Topping, Didier Merciris, Sven Lindemann

Arthritis Res Ther· April 2021

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BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation.
Tanja Mang, Kerstin Kleinschmidt-Doerr, Frank Ploeger, Andreas Schoenemann, Sven Lindemann

J Cell Sci· August 2020

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The Anti-ADAMTS-5 Nanobody M6495 Protects Cartilage Degradation Ex Vivo.
Anne Sofie Siebuhr, Daniela Werkmann, Anne-C Bay-Jensen, Christian S Thudium, Morten Asser Karsdal, Sven Lindemann

Int J Mol Sci· August 2020

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The GDF-5 mutant M1673 exerts robust anabolic and anti-catabolic effects in chondrocytes.
Tanja Mang, Kerstin Kleinschmidt-Dörr, Frank Ploeger, Sven Lindemann, Anne Gigout

J Cell Mol Med· July 2020

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Effects of Sprifermin, IGF1, IGF2, BMP7, or CNP on Bovine Chondrocytes in Monolayer and 3D Culture.
Sylvia Müller, Sven Lindemann, Anne Gigout

J Orthop Res· March 2020

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Importance of Osmolarity and Oxygen Tension for Cartilage Tissue Engineering.
Stefan Sieber, Martin Michaelis, Hans Gühring, Sven Lindemann, Anne Gigout

Biores Open Access· March 2020

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Increasing the Medium Osmolarity Reduces the Inflammatory Status of Human OA Chondrocytes and Increases Their Responsiveness to GDF-5.
Tanja Mang, Sven Lindemann, Anne Gigout

Int J Mol Sci· January 2020

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Structure-based optimization of non-peptidic Cathepsin D inhibitors.
Ulrich Grädler, Paul Czodrowski, Christos Tsaklakidis, Markus Klein, Daniela Werkmann, Sven Lindemann

Bioorg Med Chem Lett· September 2014

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Receptor fingerprinting the circling ci2 rat mutant: insights into brain asymmetry and motor control.
Nicola Palomero-Gallagher, Axel Schleicher, Sven Lindemann, Alina Lessenich, Karl Zilles

Exp Neurol· April 2008

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Comparative analysis of anxiety-like behaviors and sensorimotor functions in two rat mutants, ci2 and ci3, with lateralized rotational behavior.
Sven Lindemann, Manuela Gernert, Mustapha Bennay, Michael Koch, Wolfgang Löscher

Physiol Behav· August 2007

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Marked differences in response to dopamine receptor antagonism in two rat mutants, ci2 and ci3, with lateralized rotational behavior.
Marko Schirmer, Alina Lessenich, Sven Lindemann, Wolfgang Löscher

Behav Brain Res· June 2007

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Auditory and vestibular defects and behavioral alterations after neonatal administration of streptomycin to Lewis rats: Similarities and differences to the circling (ci2/ci2) Lewis rat mutant.
Marko Schirmer, Alexander Kaiser, Alina Lessenich, Sven Lindemann, Maren Fedrowitz

Brain Res· June 2007

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