Publications by authors named "Swetha Murthy"

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Targeting Tmem63b and Piezo2 in C-fiber low-threshold mechanoreceptors: Limitation of Vglut3-IRES-Cre.
Daniel J Orlin, Antonio Muñoz, Sage Berryman, Destinee Semidey, Swetha E Murthy

Biophys J· December 2025

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TMEM63A, associated with hypomyelinating leukodystrophies, is an evolutionarily conserved regulator of myelination.
Julia Halford, Amanda J Senatore, Sage Berryman, Antonio Muñoz, Destinee Semidey, Swetha E Murthy

Proc Natl Acad Sci U S A· July 2025

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Targeting and in C-fiber low threshold mechanoreceptor: limitation of -IRES-.
Daniel J Orlin, Antonio Munoz, Sage Berryman, Destinee Semidey, Swetha E Murthy

bioRxiv· July 2025

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Molecular architecture of TMEM63 mechanosensitive ion channels.
Jed T Syrenne, Parshuram J Sonawane, Swetha E Murthy

Cell Calcium· November 2023

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TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Wang Zheng, Shaun Rawson, Zhangfei Shen, Elakkiya Tamilselvan, Harper E Smith, Swetha E Murthy

Neuron· October 2023

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Deciphering mechanically activated ion channels at the single-channel level in dorsal root ganglion neurons.
Swetha E Murthy

J Gen Physiol· June 2023

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Glycine-bound NMDA receptors are stretch-activated.
Swetha E Murthy

Trends Neurosci· November 2022

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Transcription factor Acj6 controls dendrite targeting via a combinatorial cell-surface code.
Qijing Xie, Jiefu Li, Hongjie Li, Namrata D Udeshi, Tanya Svinkina, Swetha E Murthy

Neuron· July 2022

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Author Correction: Structure of the mechanically activated ion channel Piezo1.
Kei Saotome, Swetha E Murthy, Jennifer M Kefauver, Tess Whitwam, Ardem Patapoutian

Nature· July 2022

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Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Sebastian Jojoa-Cruz, Kei Saotome, Che Chun Alex Tsui, Wen-Hsin Lee, Mark S P Sansom, Swetha E Murthy

Nat Commun· February 2022

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Stretch-activated ion channels identified in the touch-sensitive structures of carnivorous Droseraceae plants.
Carl Procko, Swetha Murthy, William T Keenan, Seyed Ali Reza Mousavi, Tsegaye Dabi

Elife· March 2021

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Heterozygous Variants in the Mechanosensitive Ion Channel TMEM63A Result in Transient Hypomyelination during Infancy.
Huifang Yan, Guy Helman, Swetha E Murthy, Haoran Ji, Joanna Crawford

Am J Hum Genet· November 2019

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The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration.
Yuanquan Song, Dan Li, Olivia Farrelly, Leann Miles, Feng Li, Swetha E Murthy

Neuron· April 2019

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OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels.
Swetha E Murthy, Adrienne E Dubin, Tess Whitwam, Sebastian Jojoa-Cruz, Stuart M Cahalan

Elife· November 2018

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Cryo-EM structure of the mechanically activated ion channel OSCA1.2.
Sebastian Jojoa-Cruz, Kei Saotome, Swetha E Murthy, Che Chun Alex Tsui, Mark Sp Sansom

Elife· November 2018

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The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice.
Swetha E Murthy, Meaghan C Loud, Ihab Daou, Kara L Marshall, Frederick Schwaller

Sci Transl Med· October 2018

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Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection.
Shang Ma, Stuart Cahalan, Gregory LaMonte, Nathan D Grubaugh, Weizheng Zeng, Swetha E Murthy

Cell· April 2018

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Structure of the mechanically activated ion channel Piezo1.
Kei Saotome, Swetha E Murthy, Jennifer M Kefauver, Tess Whitwam, Ardem Patapoutian

Nature· February 2018

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Piezos thrive under pressure: mechanically activated ion channels in health and disease.
Swetha E Murthy, Adrienne E Dubin, Ardem Patapoutian

Nat Rev Mol Cell Biol· December 2017

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Quercetin exhibits adjuvant activity by enhancing Th2 immune response in ovalbumin immunized mice.
Divya Singh, Himanshi Tanwar, Bindhya Jayashankar, Jyoti Sharma, Swetha Murthy

Biomed Pharmacother· June 2017

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Editorial Note to: Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization.
Adrienne E Dubin, Swetha Murthy, Amanda H Lewis, Lucie Brosse, Stuart M Cahalan

Neuron· April 2017

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Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization.
Adrienne E Dubin, Swetha Murthy, Amanda H Lewis, Lucie Brosse, Stuart M Cahalan

Neuron· April 2017

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Augmentation of humoral and cellular immunity in response to Tetanus and Diphtheria toxoids by supercritical carbon dioxide extracts of Hippophae rhamnoides L. leaves.
Bindhya Jayashankar, Divya Singh, Himanshi Tanwar, K P Mishra, Swetha Murthy

Int Immunopharmacol· March 2017

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LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.
Ruhma Syeda, Zhaozhu Qiu, Adrienne E Dubin, Swetha E Murthy, Maria N Florendo

Cell· January 2016

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Piezo1 ion channel pore properties are dictated by C-terminal region.
Bertrand Coste, Swetha E Murthy, Jayanti Mathur, Manuela Schmidt, Yasmine Mechioukhi

Nat Commun· May 2015

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