Publications by authors named "TS Powers"

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Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease.
Jian Jeffrey Chen, Qingyian Liu, Chester Yuan, Vijay Gore, Patricia Lopez, Timothy S Powers

Bioorg Med Chem Lett· February 2015

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An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities.
Yuan Cheng, James Brown, Ted C Judd, Patricia Lopez, Wenyuan Qian, Timothy S Powers

ACS Med Chem Lett· February 2015

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Discovery and evaluation of a non-Zn chelating, selective matrix metalloproteinase 13 (MMP-13) inhibitor for potential intra-articular treatment of osteoarthritis.
Christian Gege, Bagna Bao, Harald Bluhm, Jürgen Boer, Brian M Gallagher, Timothy S Powers

J Med Chem· January 2012

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From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1).
Yuan Cheng, Ted C Judd, Michael D Bartberger, James Brown, Kui Chen, Timothy S Powers

J Med Chem· August 2011

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A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models.
Vijaykumar M Baragi, Gabriel Becher, Alison M Bendele, Ralf Biesinger, Harald Bluhm, Timothy S Powers

Arthritis Rheum· July 2009

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Combinatorial Materials Science and Catalysis.
B Jandeleit, DJ Schaefer, TS Powers, HW Turner, WH Weinberg

Angew Chem Int Ed Engl· September 1999

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Solid-Phase Synthesis and Encoding Strategies for Olefin Polymerization Catalyst Libraries.
Thomas R Boussie, Carla Coutard, Howard Turner, Vince Murphy, Timothy S Powers

Angew Chem Int Ed Engl· December 1998

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The design and synthesis of substituted biphenyl libraries.
M R Pavia, M P Cohen, G J Dilley, G R Dubuc, T L Durgin, T S Powers

Bioorg Med Chem· May 1996

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Multiple simultaneous synthesis of phenolic libraries.
H V Meyers, G J Dilley, T L Durgin, T S Powers, N A Winssinger

Mol Divers· September 1995

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Criteria for selecting a contract emergency group.
T S Powers

J Ambul Care Mark· September 1989

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