Publications by authors named "Tadatoshi Hashimoto"

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Mechanisms of inhibitory action of TRK-130 (Naltalimide), a μ-opioid receptor partial agonist, on the micturition reflex.
Morihiro Fujimura, Naoki Izumimoto, Sayoko Kanie, Ryosuke Kobayashi, Satoru Yoshikawa, Tadatoshi Hashimoto

Int Urol Nephrol· April 2017

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Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.
Hidetoshi Komatsu, Minoru Maruyama, Shuuhei Yao, Tokuyuki Shinohara, Kensuke Sakuma, Tadatoshi Hashimoto

PLoS One· October 2014

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Characteristics of TRK-130 (Naltalimide), a novel opioid ligand, as a new therapeutic agent for overactive bladder.
Morihiro Fujimura, Naoki Izumimoto, Shinobu Momen, Satoru Yoshikawa, Ryosuke Kobayashi, Tadatoshi Hashimoto

J Pharmacol Exp Ther· September 2014

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Generation of gene-targeted mice using embryonic stem cells derived from a transgenic mouse model of Alzheimer's disease.
Satoshi Yamamoto, Yuki Ooshima, Mitsugu Nakata, Takashi Yano, Kunio Matsuoka, Tadatoshi Hashimoto

Transgenic Res· June 2013

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Derivation of rat embryonic stem cells and generation of protease-activated receptor-2 knockout rats.
Satoshi Yamamoto, Mitsugu Nakata, Reiko Sasada, Yuki Ooshima, Takashi Yano, Tadatoshi Hashimoto

Transgenic Res· August 2012

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Hypercholesterolemia and atherosclerosis in low density lipoprotein receptor mutant rats.
Makoto Asahina, Tomoji Mashimo, Michiyasu Takeyama, Ryuichi Tozawa, Tadatoshi Hashimoto

Biochem Biophys Res Commun· February 2012

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Novel 3-phenylpiperidine-4-carboxamides as highly potent and orally long-acting neurokinin-1 receptor antagonists with reduced CYP3A induction.
Junya Shirai, Hideyuki Sugiyama, Shinji Morimoto, Hironobu Maezaki, Yasuharu Yamamoto, Tadatoshi Hashimoto

Bioorg Med Chem· January 2012

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Design, structure-activity relationship, and highly efficient asymmetric synthesis of 3-phenyl-4-benzylaminopiperidine derivatives as novel neurokinin-1 receptor antagonists.
Junya Shirai, Takeshi Yoshikawa, Masayuki Yamashita, Yasuharu Yamamoto, Makiko Kawamoto, Tadatoshi Hashimoto

Bioorg Med Chem· November 2011

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Apelin-transgenic mice exhibit a resistance against diet-induced obesity by increasing vascular mass and mitochondrial biogenesis in skeletal muscle.
Toshihiro Yamamoto, Yugo Habata, Yoshio Matsumoto, Yoshitaka Yasuhara, Tadatoshi Hashimoto

Biochim Biophys Acta· September 2011

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3-benzhydryl-4-piperidones as novel neurokinin-1 receptor antagonists and their efficient synthesis.
Junya Shirai, Masayoshi Yamaoka, Eikoh Imamiya, Minoru Nakamura, Naoki Tarui, Tadatoshi Hashimoto

Bioorg Med Chem· September 2011

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Involvement of reflex urethral closure mechanisms in urethral resistance under momentary stress condition induced by electrical stimulation of rat abdomen.
Izumi Kamo, Tadatoshi Hashimoto

Am J Physiol Renal Physiol· September 2007

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Effects of the selective acetylcholinesterase inhibitor TAK-802 on the voiding behavior and bladder mass increase in rats with partial bladder outlet obstruction.
Tadatoshi Hashimoto, Hiroshi Nagabukuro, Takayuki Doi

J Urol· September 2005

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Effects of TAK-802, a novel acetylcholinesterase inhibitor, and tamsulosin, an alpha1-adrenoceptor antagonist, and their synergistic effects on the urodynamic characteristics in a guinea-pig model of functional bladder outlet obstruction.
Hiroshi Nagabukuro, Tadatoshi Hashimoto, Masashi Iwata, Takayuki Doi

BJU Int· May 2005

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