Publications by authors named "Tanya MacNeil"

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Variables in Cryosurgery Technique Associated With Clearance of Actinic Keratosis.
Brian Berman, Arsalan Qazi Shabbir, Tanya MacNeil, Kim Mark Knudsen

Dermatol Surg· March 2017

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Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.
Qingmei Hong, Raman K Bakshi, Brenda L Palucki, Min K Park, Zhixiong Ye, Tanya MacNeil

Bioorg Med Chem Lett· April 2011

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Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity.
Shuwen He, Zhixiong Ye, Peter H Dobbelaar, Raman K Bakshi, Qingmei Hong, Tanya MacNeil

Bioorg Med Chem Lett· November 2010

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SERMs: progress and future perspectives.
James H Pickar, Tanya MacNeil, Kathleen Ohleth

Maturitas· October 2010

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Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands.
Qingmei Hong, Raman K Bakshi, James Dellureficio, Shuwen He, Zhixiong Ye, Tanya Macneil

Bioorg Med Chem Lett· August 2010

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Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity.
Shuwen He, Zhixiong Ye, Peter H Dobbelaar, Iyassu K Sebhat, Liangqin Guo, Tanya Macneil

Bioorg Med Chem Lett· August 2010

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Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.
Liangqin Guo, Zhixiong Ye, Jian Liu, Shuwen He, Raman K Bakshi, Tanya MacNeil

Bioorg Med Chem Lett· August 2010

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Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist.
Shuwen He, Zhixiong Ye, Peter H Dobbelaar, Iyassu K Sebhat, Liangqin Guo, Tanya Macneil

Bioorg Med Chem Lett· April 2010

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Potent and selective peptide agonists for human melanocortin receptor 5.
Maria A Bednarek, Tanya MacNeil, Rui Tang, M Angeles Cabello, Marta Maroto

Adv Exp Med Biol· June 2009

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Cyclic analogs of alpha-melanocyte-stimulating hormone (alphaMSH) with high agonist potency and selectivity at human melanocortin receptor 1b.
Maria A Bednarek, Tanya MacNeil, Rui Tang, Tung M Fong, M Angeles Cabello

Peptides· June 2008

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Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators.
Liangqin Guo, Zhixiong Ye, Feroze Ujjainwalla, Heather L Sings, Iyassu K Sebhat, Tanya MacNeil

Bioorg Med Chem Lett· June 2008

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Analogs of alpha-melanocyte stimulating hormone with high agonist potency and selectivity at human melanocortin receptor 1b: the role of Trp(9) in molecular recognition.
Maria A Bednarek, Tanya Macneil, Rui Tang, Tung M Fong, M Angeles Cabello

Biopolymers· May 2008

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Melanocortin subtype 4 receptor agonists: structure-activity relationships about the 4-alkyl piperidine core.
Iyassu K Sebhat, Yingjie Lai, Khaled Barakat, Zhixiong Ye, Rui Tang, Tanya Macneil

Bioorg Med Chem Lett· October 2007

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Potent and selective agonists of alpha-melanotropin (alphaMSH) action at human melanocortin receptor 5; linear analogs of alpha-melanotropin.
Maria A Bednarek, Tanya MacNeil, Rui Tang, Tung M Fong, M Angeles Cabello

Peptides· May 2007

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Potent and selective agonists of human melanocortin receptor 5: cyclic analogues of alpha-melanocyte-stimulating hormone.
Maria A Bednarek, Tanya MacNeil, Rui Tang, Tung M Fong, M Angeles Cabello

J Med Chem· May 2007

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Potent and selective peptide agonists of alpha-melanocyte stimulating hormone (alphaMSH) action at human melanocortin receptor 5; their synthesis and biological evaluation in vitro.
Maria A Bednarek, Tanya MacNeil, Rui Tang, Tung M Fong, M Angeles Cabello

Chem Biol Drug Des· May 2007

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Optimization of a privileged structure leading to potent and selective human melanocortin subtype-4 receptor ligands.
Raman K Bakshi, Qingmei Hong, Rui Tang, Rubana N Kalyani, Tanya Macneil

Bioorg Med Chem Lett· March 2006

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Structure-activity relationship of linear tetrapeptides Tic-DPhe-Arg-Trp-NH2 at the human melanocortin-4 receptor and effects on feeding behaviors in rat.
Zhixiong Ye, Tanya MacNeil, David H Weinberg, Rubana N Kalyani, Rui Tang

Peptides· October 2005

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Design and syntheses of melanocortin subtype-4 receptor agonists. Part 2: discovery of the dihydropyridazinone motif.
Feroze Ujjainwalla, Daniel Warner, Christine Snedden, Ricky D Grisson, Thomas F Walsh, Tanya Macneil

Bioorg Med Chem Lett· September 2005

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Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2-azabicyclo[2.2.2]octane-6-carboxamide (3, RY764), a potent and selective melanocortin subtype-4 receptor agonist.
Zhixiong Ye, Liangqin Guo, Khaled J Barakat, Patrick G Pollard, Brenda L Palucki, Tanya MacNeil

Bioorg Med Chem Lett· August 2005

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1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: application in the synthesis of potent human melanocortin-4 receptor selective agonists.
Raman K Bakshi, Qingmei Hong, J T Olson, Zhixiong Ye, Iyassue K Sebhat, Tanya MacNeil

Bioorg Med Chem Lett· July 2005

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2,3-Diaminopyridine as a platform for designing structurally unique nonpeptide bradykinin B1 receptor antagonists.
Dong-Mei Feng, Jenny M Wai, Scott D Kuduk, Christina Ng, Kathy L Murphy, Tanya MacNeil

Bioorg Med Chem Lett· May 2005

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2-Piperazinecarboxamides as potent and selective melanocortin subtype-4 receptor agonists.
Brenda L Palucki, Min K Park, Ravi P Nargund, Rui Tang, Tanya MacNeil

Bioorg Med Chem Lett· April 2005

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Discovery of (2S)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-4-methyl-2-piperazinecarboxamide (MB243), a potent and selective melanocortin subtype-4 receptor agonist.
Brenda L Palucki, Min K Park, Ravi P Nargund, Zhixiong Ye, Iyassu K Sebhat, Tanya Macneil

Bioorg Med Chem Lett· January 2005

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Design and syntheses of melanocortin subtype-4 receptor agonists: evolution of the pyridazinone archetype.
Feroze Ujjainwalla, Daniel Warner, Thomas F Walsh, Matthew J Wyvratt, Changyou Zhou, Tanya MacNeil

Bioorg Med Chem Lett· December 2003

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