Publications by authors named "Taylor L Mighell"

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A small molecule stabilizer rescues the surface expression of nearly all missense variants in a GPCR.
Taylor L Mighell, Ben Lehner

Nat Struct Mol Biol· December 2025

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Author Correction: A small molecule stabilizer rescues the surface expression of nearly all missense variants in a GPCR.
Taylor L Mighell, Ben Lehner

Nat Struct Mol Biol· December 2025

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SUNi mutagenesis: Scalable and uniform nicking for efficient generation of variant libraries.
Taylor L Mighell, Ignasi Toledano, Ben Lehner

PLoS One· July 2023

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Cas12a-Capture: A Novel, Low-Cost, and Scalable Method for Targeted Sequencing.
Taylor L Mighell, Andrew Nishida, Brendan L O'Connell, Caitlin V Miller, Sally Grindstaff

CRISPR J· August 2022

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A Sort-Seq Approach to the Development of Single Fluorescent Protein Biosensors.
John N Koberstein, Melissa L Stewart, Taylor L Mighell, Chadwick B Smith, Michael S Cohen

ACS Chem Biol· September 2021

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AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria.
Daelyn Y Richards, Shelley R Winn, Sandra Dudley, Sean Nygaard, Taylor L Mighell

Mol Ther Methods Clin Dev· June 2020

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An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships.
Taylor L Mighell, Stetson Thacker, Eric Fombonne, Charis Eng, Brian J O'Roak

Am J Hum Genet· June 2020

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A Saturation Mutagenesis Approach to Understanding PTEN Lipid Phosphatase Activity and Genotype-Phenotype Relationships.
Taylor L Mighell, Sara Evans-Dutson, Brian J O'Roak

Am J Hum Genet· May 2018

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