Publications by authors named "Sean Nygaard"

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Therapeutic liver repopulation by transient acetaminophen selection of gene-modified hepatocytes.
Anne Vonada, Amita Tiyaboonchai, Sean Nygaard, Jeffrey Posey, Alexander Mack Peters

Sci Transl Med· June 2021

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Induced Liver Regeneration Enhances CRISPR/Cas9-Mediated Gene Repair in Tyrosinemia Type 1.
Qing-Shuo Zhang, Amita Tiyaboonchai, Sean Nygaard, Kevin Baradar, Angela Major

Hum Gene Ther· March 2021

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AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria.
Daelyn Y Richards, Shelley R Winn, Sandra Dudley, Sean Nygaard, Taylor L Mighell

Mol Ther Methods Clin Dev· June 2020

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Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors.
Katja Pekrun, Gustavo De Alencastro, Qing-Jun Luo, Jun Liu, Youngjin Kim, Sean Nygaard

JCI Insight· November 2019

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Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Nicole K Paulk, Katja Pekrun, Erhua Zhu, Sean Nygaard, Bin Li

Mol Ther· January 2018

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A universal system to select gene-modified hepatocytes in vivo.
Sean Nygaard, Adi Barzel, Annelise Haft, Angela Major, Milton Finegold

Sci Transl Med· June 2016

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Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.
Leszek Lisowski, Allison P Dane, Kirk Chu, Yue Zhang, Sharon C Cunningham, Sean Nygaard

Nature· February 2014

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Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors.
Dale A Fortin, Taasin Srivastava, Diya Dwarakanath, Philippe Pierre, Sean Nygaard

J Neurosci· June 2012

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Regulation of neuronal mRNA translation by CaM-kinase I phosphorylation of eIF4GII.
Taasin Srivastava, Dale A Fortin, Sean Nygaard, Stefanie Kaech, Nahum Sonenberg

J Neurosci· April 2012

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Long-term potentiation-dependent spine enlargement requires synaptic Ca2+-permeable AMPA receptors recruited by CaM-kinase I.
Dale A Fortin, Monika A Davare, Taasin Srivastava, James D Brady, Sean Nygaard

J Neurosci· September 2010

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Transient receptor potential canonical 5 channels activate Ca2+/calmodulin kinase Igamma to promote axon formation in hippocampal neurons.
Monika A Davare, Dale A Fortin, Takeo Saneyoshi, Sean Nygaard, Stefanie Kaech

J Neurosci· August 2009

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Inhibition of calcium/calmodulin-dependent protein kinase kinase by protein 14-3-3.
Monika A Davare, Takeo Saneyoshi, Eric S Guire, Sean C Nygaard, Thomas R Soderling

J Biol Chem· December 2004

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