Publications by authors named "Kirk Chu"

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A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice.
Hak Kyun Kim, Jianpeng Xu, Kirk Chu, Hyesuk Park, Hagoon Jang

Cell Rep· December 2019

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miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression.
Paul N Valdmanis, Hak Kyun Kim, Kirk Chu, Feijie Zhang, Jianpeng Xu

Nat Commun· December 2018

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Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Nicole K Paulk, Katja Pekrun, Erhua Zhu, Sean Nygaard, Bin Li, Kirk Chu

Mol Ther· January 2018

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A transfer-RNA-derived small RNA regulates ribosome biogenesis.
Hak Kyun Kim, Gabriele Fuchs, Shengchun Wang, Wei Wei, Yue Zhang, Kirk Chu, Mei-Sze Chua

Nature· December 2017

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A 5' Noncoding Exon Containing Engineered Intron Enhances Transgene Expression from Recombinant AAV Vectors in vivo.
Jiamiao Lu, James A Williams, Jeremy Luke, Feijie Zhang, Kirk Chu

Hum Gene Ther· January 2017

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RNA interference-induced hepatotoxicity results from loss of the first synthesized isoform of microRNA-122 in mice.
Paul N Valdmanis, Shuo Gu, Kirk Chu, Lan Jin, Feijie Zhang

Nat Med· May 2016

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Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant.
Sandra P Melo, Leszek Lisowski, Elizaveta Bashkirova, Hanson H Zhen, Kirk Chu

Mol Ther· April 2014

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Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.
Leszek Lisowski, Allison P Dane, Kirk Chu, Yue Zhang, Sharon C Cunningham

Nature· February 2014

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Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.
Mustafa N Yazicioglu, Luca Monaldini, Kirk Chu, Fayaz R Khazi, Samuel L Murphy

J Biol Chem· September 2013

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A concept of eliminating nonhomologous recombination for scalable and safe AAV vector generation for human gene therapy.
Biao Dong, Andrea R Moore, Jihong Dai, Sean Roberts, Kirk Chu

Nucleic Acids Res· July 2013

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The anti-genomic (negative) strand of Hepatitis C Virus is not targetable by shRNA.
Leszek Lisowski, Menashe Elazar, Kirk Chu, Jeffrey S Glenn, Mark A Kay

Nucleic Acids Res· April 2013

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