Publications by authors named "Tennore Ramesh"

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Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo.
Liam Kempthorne, Deniz Vaizoglu, Alexander J Cammack, Mireia Carcolé, Martha J Roberts, Tennore M Ramesh

Nat Commun· January 2025

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RAN Translation of C9orf72-Related Dipeptide Repeat Proteins in Zebrafish Recapitulates Hallmarks of Amyotrophic Lateral Sclerosis and Identifies Hypothermia as a Therapeutic Strategy.
David J Burrows, Alexander McGown, Olfat Abduljabbar, Lydia M Castelli, Pamela J Shaw, Tennore M Ramesh

Ann Neurol· December 2024

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Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis.
Sarah Boddy, Mahjabin Islam, Tobias Moll, Julian Kurz, David Burrows, Tennore Ramesh

Brain Commun· March 2022

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The effect of hyperglycemia on neurovascular coupling and cerebrovascular patterning in zebrafish.
Karishma Chhabria, Karen Plant, Oliver Bandmann, Robert N Wilkinson, Chris Martin, Tennore Ramesh

J Cereb Blood Flow Metab· February 2020

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Animal models of multiple sclerosis: From rodents to zebrafish.
David John Burrows, Alexander McGown, Saurabh A Jain, Milena De Felice, Tennore M Ramesh

Mult Scler· March 2019

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Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis.
Johnathan Cooper-Knock, Tobias Moll, Tennore Ramesh, Lydia Castelli, Alexander Beer

Cell Rep· February 2019

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Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
Matthew P Shaw, Adrian Higginbottom, Alexander McGown, Lydia M Castelli, Evlyn James, Tennore M Ramesh

Acta Neuropathol Commun· November 2018

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Axonal Transport Defects in a Mitofusin 2 Loss of Function Model of Charcot-Marie-Tooth Disease in Zebrafish.
Anna L Chapman, Ellen J Bennett, Tennore M Ramesh, Kurt J De Vos, Andrew J Grierson

PLoS One· October 2017

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ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis.
Alexander McGown, Dame Pamela J Shaw, Tennore Ramesh

Mol Neurodegener· July 2016

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A zebrafish model exemplifies the long preclinical period of motor neuron disease.
Tennore M Ramesh, Pamela J Shaw, Jonathan McDearmid

J Neurol Neurosurg Psychiatry· November 2014

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Abnormalities in whisking behaviour are associated with lesions in brain stem nuclei in a mouse model of amyotrophic lateral sclerosis.
Robyn A Grant, Paul S Sharp, Aneurin J Kennerley, Jason Berwick, Andrew Grierson, Tennore Ramesh

Behav Brain Res· February 2014

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A new zebrafish model produced by TILLING of SOD1-related amyotrophic lateral sclerosis replicates key features of the disease and represents a tool for in vivo therapeutic screening.
Marc M J Da Costa, Claire E Allen, Adrian Higginbottom, Tennore Ramesh, Pamela J Shaw

Dis Model Mech· January 2014

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Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish.
Channa A A Hewamadduma, Andrew J Grierson, Taylur P Ma, Luyuan Pan, Cecilia B Moens, Tennore Ramesh

Hum Mol Genet· June 2013

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Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model.
Alexander McGown, Jonathan R McDearmid, Niki Panagiotaki, Huaxia Tong, Sufana Al Mashhadi, Tennore M Ramesh

Ann Neurol· February 2013

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A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease.
Tennore Ramesh, Alison N Lyon, Ricardo H Pineda, Chunping Wang, Paul M L Janssen

Dis Model Mech· December 2010

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Report of the European Zebrafish Principal Investigator Meeting in Padua, Italy, March 18–22, 2010.
Caroline Brennan, Roland Dosch, Anna-Pavlina Haramis, Till Luckenbach, Juan-Ramon Martinez-Morales, Tennore M Ramesh

Zebrafish· September 2010

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Determination of clodronate content in liposomal formulation by capillary zone electrophoresis.
Pál Perjési, Taewook Kim, Alevtina D Zharikova, Xiaoxu Li, Tennore Ramesh

J Pharm Biomed Anal· April 2003

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Novel trends in orphan market drug discovery: amyotrophic lateral sclerosis as a case study.
Jennifer E Clark, Avis Brennan, Tennore M Ramesh, James Allen Heywood

Front Biosci· August 2002

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