Publications by authors named "Terry A Hauser"

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T
The effect of food and liquid pH on the integrity of enteric-coated beads from cysteamine bitartrate delayed-release capsules.
Nadine Pavloff, Terry A Hauser, Chris Williams, Sara Louis Isbell, Ben Cadieux

Drug Des Devel Ther· February 2019

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QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at the α4β2 and α3β4 nicotinic acetylcholine receptors (nAChRs).
David C Kombo, Vladimir P Grinevich, Terry A Hauser, Serguei Sidach, Merouane Bencherif

Bioorg Med Chem Lett· September 2013

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Novel nicotinic acetylcholine receptor agonists containing carbonyl moiety as a hydrogen bond acceptor.
Anatoly A Mazurov, David C Kombo, Srinivasa Akireddy, Srinivasa Murthy, Terry A Hauser

Bioorg Med Chem Lett· July 2013

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Pharmacological properties and predicted binding mode of arylmethylene quinuclidine-like derivatives at the α3β4 nicotinic acetylcholine receptor (nAChR).
David C Kombo, Terry A Hauser, Vladimir P Grinevich, Matthew S Melvin, Jon-Paul Strachan

Bioorg Med Chem Lett· March 2013

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3D molecular descriptors important for clinical success.
David C Kombo, Kartik Tallapragada, Rachit Jain, Joseph Chewning, Anatoly A Mazurov, Terry A Hauser

J Chem Inf Model· February 2013

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Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: correlation with desensitization of α4β2* receptors.
Jiahui Zhang, Yun-De Xiao, Kristen G Jordan, Phil S Hammond, Katherine M Van Dyke, Terry A Hauser

Eur J Pharm Sci· December 2012

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Discovery of 3-(5-chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a novel highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders.
Anatoly A Mazurov, Lan Miao, Balwinder S Bhatti, Jon-Paul Strachan, Srinivasa Akireddy, Terry A Hauser

J Med Chem· November 2012

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Discovery of (2S,3R)-N-[2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]benzo[b]furan-2-carboxamide (TC-5619), a selective α7 nicotinic acetylcholine receptor agonist, for the treatment of cognitive disorders.
Anatoly A Mazurov, David C Kombo, Terry A Hauser, Lan Miao, Gary Dull

J Med Chem· November 2012

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Comparison of acetylcholine receptor interactions of the marine toxins, 13-desmethylspirolide C and gymnodimine.
Terry A Hauser, Christopher D Hepler, David C Kombo, Vladimir P Grinevich, Melanie N Kiser

Neuropharmacology· June 2012

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Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs.
David C Kombo, Anatoly A Mazurov, Joseph Chewning, Philip S Hammond, Kartik Tallapragada, Terry A Hauser

Bioorg Med Chem Lett· January 2012

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Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands.
David C Kombo, Anatoly Mazurov, Kartik Tallapragada, Philip S Hammond, Joseph Chewning, Terry A Hauser

Eur J Med Chem· November 2011

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An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes.
Mario B Marrero, Rudolf Lucas, Christina Salet, Terry A Hauser, Anatoly Mazurov

J Pharmacol Exp Ther· January 2010

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First total synthesis of (+/-)-3-hydroxy-11-norcytisine: structure confirmation and biological characterization.
Daniel Yohannes, Camilla P Hansen, Srinivasa Rao Akireddy, Terry A Hauser, Melanie N Kiser

Org Lett· December 2008

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Therapeutic potential of novel selective drugs targeting nicotinic acetylcholine receptors.
Merouane Bencherif, Terry A Hauser, Kristen G Jordan, Gregory J Gatto

J Mol Neurosci· February 2007

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2-(Arylmethyl)-3-substituted quinuclidines as selective alpha 7 nicotinic receptor ligands.
Anatoly Mazurov, Jozef Klucik, Lan Miao, Teresa Y Phillips, Angela Seamans, Terry A Hauser

Bioorg Med Chem Lett· April 2005

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