Publications by authors named "Merouane Bencherif"

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TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors.
Teagan R Wall, Brandon J Henderson, George Voren, Charles R Wageman, Purnima Deshpande, Merouane Bencherif

Front Pharmacol· September 2017

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Alpha7 neuronal nicotinic receptor: a pluripotent target for diseases of the central nervous system.
Merouane Bencherif, Sridhar T Narla, Michal S Stachowiak

CNS Neurol Disord Drug Targets· March 2015

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The effects of varenicline on sensory gating and exploratory behavior with pretreatment with nicotinic or 5-HT3A receptor antagonists.
Aaron Kucinski, Scott Wersinger, Ewa K Stachowiak, Chani Becker, Pat Lippiello, Merouane Bencherif

Behav Pharmacol· February 2015

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Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs).
Jon-Paul Strachan, David C Kombo, Anatoly Mazurov, Ronald Heemstra, Balwinder S Bhatti, Merouane Bencherif

Eur J Med Chem· October 2014

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Understanding the role α7 nicotinic receptors play in dopamine efflux in nucleus accumbens.
Reinoud Maex, Vladimir P Grinevich, Valentina Grinevich, Evgeny Budygin, Merouane Bencherif

ACS Chem Neurosci· October 2014

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Comparative study on the use of docking and Bayesian categorization to predict ligand binding to nicotinic acetylcholine receptors (nAChRs) subtypes.
David C Kombo, Merouane Bencherif

J Chem Inf Model· December 2013

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Neuronal nicotinic receptor agonists ameliorate spontaneous motor asymmetries and motor discoordination in a unilateral mouse model of Parkinson's disease.
Aaron Kucinski, Scott Wersinger, Ewa K Stachowiak, Thomas D Corso, Matthew J Parry, Merouane Bencherif

Pharmacol Biochem Behav· October 2013

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Nicotinic receptor agonists reduce L-DOPA-induced dyskinesias in a monkey model of Parkinson's disease.
Danhui Zhang, Archana Mallela, David Sohn, F Ivy Carroll, Merouane Bencherif

J Pharmacol Exp Ther· October 2013

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α7 nicotinic receptor agonist reactivates neurogenesis in adult brain.
Sridhar Narla, Ilona Klejbor, Barbara Birkaya, Yu-Wei Lee, Janusz Morys, Merouane Bencherif

Biochem Pharmacol· October 2013

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Activation of developmental nuclear fibroblast growth factor receptor 1 signaling and neurogenesis in adult brain by α7 nicotinic receptor agonist.
Sridhar T Narla, Ilona Klejbor, Barbara Birkaya, Yu-Wei Lee, Janusz Morys, Merouane Bencherif

Stem Cells Transl Med· October 2013

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QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at the α4β2 and α3β4 nicotinic acetylcholine receptors (nAChRs).
David C Kombo, Vladimir P Grinevich, Terry A Hauser, Serguei Sidach, Merouane Bencherif

Bioorg Med Chem Lett· September 2013

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Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with α4β2 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes.
David C Kombo, Anatoly A Mazurov, Jon-Paul Strachan, Merouane Bencherif

Bioorg Med Chem Lett· September 2013

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Validation of a high-throughput, automated electrophysiology platform for the screening of nicotinic agonists and antagonists.
John D Graef, Lisa C Benson, Serguei S Sidach, Haiyang Wei, Patrick M Lippiello, Merouane Bencherif

J Biomol Screen· January 2013

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Slice XVIvoâ„¢: a novel electrophysiology system with the capability for 16 independent brain slice recordings.
John D Graef, Haiyang Wei, Patrick M Lippiello, Merouane Bencherif, Nikolai Fedorov

J Neurosci Methods· January 2013

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Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: correlation with desensitization of α4β2* receptors.
Jiahui Zhang, Yun-De Xiao, Kristen G Jordan, Phil S Hammond, Katherine M Van Dyke, Merouane Bencherif

Eur J Pharm Sci· December 2012

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Alpha7 nicotinic cholinergic neuromodulation may reconcile multiple neurotransmitter hypotheses of schizophrenia.
Merouane Bencherif, Michal K Stachowiak, Aaron J Kucinski, Patrick M Lippiello

Med Hypotheses· May 2012

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A method for bidirectional solution exchange--"liquid bullet" applications of acetylcholine to α7 nicotinic receptors.
Nikolai Fedorov, Lisa Benson, John D Graef, Jeremy Hyman, Jill Sollenberger, Merouane Bencherif

J Neurosci Methods· April 2012

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Alpha7 nicotinic receptors as novel therapeutic targets for inflammation-based diseases.
Merouane Bencherif, Patrick M Lippiello, Rudolf Lucas, Mario B Marrero

Cell Mol Life Sci· March 2011

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Alpha7 neuronal nicotinic receptors as targets for novel therapies to treat multiple domains of schizophrenia.
Aaron J Kucinski, Michal K Stachowiak, Scott R Wersinger, Patrick M Lippiello, Merouane Bencherif

Curr Pharm Biotechnol· March 2011

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Application of alpha7 nicotinic acetylcholine receptor agonists in inflammatory diseases: an overview.
Mario B Marrero, Merouane Bencherif, Patrick M Lippiello, Rudolf Lucas

Pharm Res· February 2011

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Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors.
Sharon R Grady, Ryan M Drenan, Scott R Breining, Daniel Yohannes, Charles R Wageman, Merouane Bencherif

Neuropharmacology· June 2010

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Alpha7 neuronal nicotinic receptors: the missing link to understanding Alzheimer's etiopathology?
Merouane Bencherif, Patrick M Lippiello

Med Hypotheses· February 2010

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An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes.
Mario B Marrero, Rudolf Lucas, Christina Salet, Terry A Hauser, Anatoly Mazurov, Merouane Bencherif

J Pharmacol Exp Ther· January 2010

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Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype.
Scott R Breining, Merouane Bencherif, Sharon R Grady, Paul Whiteaker, Michael J Marks

Bioorg Med Chem Lett· August 2009

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Neuronal nicotinic receptors as novel targets for inflammation and neuroprotection: mechanistic considerations and clinical relevance.
Merouane Bencherif

Acta Pharmacol Sin· June 2009

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