Publications by authors named "Terry Bowlin"

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Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis.
Nathan Peroutka-Bigus, Michael S Scherman, Firat Kaya, Samanthi L Waidyarachchi, Jiuyu Liu, Terry Bowlin

Antimicrob Agents Chemother· November 2025

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Identification and Characterization of a Metal Binding-Independent Rift Valley Fever Virus Endonuclease Inhibitor.
Cara D Kirby, Gai Liu, Farheen Fatma, Maris R Pedlow, Narendran G-Dayanandan, Terry L Bowlin

ACS Infect Dis· September 2025

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Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis.
Nathan Peroutka-Bigus, Michael S Sherman, Firat Kaya, Samanthi L Waidyarachchi, Jiuyu Liu, Terry Bowlin

bioRxiv· August 2025

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N-arylpyrimidinamine (NAPA) compounds are broadly acting inhibitors of human cytomegalovirus infection and spread.
Kristina E Atanasoff, Sabrina I Ophir, Andrea J Parsons, Jailene Paredes Casado, Nell S Lurain, Terry L Bowlin

Antiviral Res· January 2025

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Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis.
Allison A Bauman, Jansy P Sarathy, Firat Kaya, Lisa M Massoudi, Michael S Scherman, Terry L Bowlin

Antimicrob Agents Chemother· November 2024

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Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis.
Allison A Bauman, Jansy P Sarathy, Firat Kaya, Lisa M Massoudi, Michael S Scherman, Terry L Bowlin

bioRxiv· May 2024

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Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus.
Andrea J Parsons, Sabrina I Ophir, Thomas J Gardner, Jailene Casado Paredes, Kathryn R Stein, Terry L Bowlin

Antiviral Res· January 2023

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Filociclovir is a potent inhibitor of human adenovirus F41.
Ann E Tollefson, Islam T M Hussein, Karoly Toth, Terry L Bowlin

Antiviral Res· December 2022

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Optimized Pyridazinone Nutrient Channel Inhibitors Are Potent and Specific Antimalarial Leads.
Michelle M Butler, Samanthi L Waidyarachchi, Jinfeng Shao, Son T Nguyen, Xiaoyuan Ding, Terry L Bowlin

Mol Pharmacol· September 2022

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Adjunctive therapy for multidrug-resistant bacterial infections: Type III secretion system and efflux inhibitors.
Donald T Moir, Timothy J Opperman, Zachary D Aron, Terry L Bowlin

Drug Discov Today· September 2021

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Pentostatin antagonizes the antiviral activity of MBX-2168 by inhibiting the biosynthesis of the active compound.
Natalie R Hagen, Marie L Nguyen, John D Williams, Terry L Bowlin, Brian G Gentry

Antiviral Res· March 2021

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trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo.
Zachary D Aron, Atousa Mehrani, Eric D Hoffer, Kristie L Connolly, Pooja Srinivas, Terry L Bowlin

Nat Commun· March 2021

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Filociclovir Is an Active Antiviral Agent against Ocular Adenovirus Isolates In Vitro and in the Ad5/NZW Rabbit Ocular Model.
Eric G Romanowski, Islam T M Hussein, Steven C Cardinale, Michelle M Butler, Lucas R Morin, Terry L Bowlin

Pharmaceuticals (Basel)· March 2021

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Filociclovir Is a Potent and Inhibitor of Human Adenoviruses.
Karoly Toth, Islam T M Hussein, Ann E Tollefson, Baoling Ying, Jacqueline F Spencer, Terry L Bowlin

Antimicrob Agents Chemother· October 2020

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A Structure-Function-Inhibition Analysis of the Type III Secretion Needle Protein PscF.
Donald T Moir, Nicholas O Bowlin, Bryan J Berube, Jaden Yabut, Debra M Mills, Terry L Bowlin

J Bacteriol· August 2020

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The discovery and development of filociclovir for the prevention and treatment of human cytomegalovirus-related disease.
Islam T M Hussein, Jennifer Brooks, Terry L Bowlin

Antiviral Res· April 2020

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Small Molecule Compounds That Inhibit Antioxidant Response Gene Expression in an Inducer-Dependent Manner.
Megan R Edwards, Gai Liu, Sampriti De, Julien Sourimant, Colette Pietzsch, Terry L Bowlin

ACS Infect Dis· March 2020

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Biosynthesis and half-life of MBX-2168-triphosphate in herpes virus-infected cells.
Hannah E Sauer, Marie L Nguyen, John D Williams, Terry L Bowlin, Brian G Gentry

Antiviral Res· March 2020

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Advances in the Development of Therapeutics for Cytomegalovirus Infections.
Edward Acosta, Terry Bowlin, Jennifer Brooks, Lillian Chiang, Islam Hussein

J Infect Dis· March 2020

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Activation of 6-Alkoxy-Substituted Methylenecyclopropane Nucleoside Analogs Requires Enzymatic Modification by Adenosine Deaminase-Like Protein 1.
Kathryn J Vollmer, Anna C Burns, Hannah E Sauer, John D Williams, Gloria Komazin-Meredith, Terry L Bowlin

Antimicrob Agents Chemother· October 2019

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Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens.
Jennifer M Scarff, Samanthi L Waidyarachchi, Christopher J Meyer, Douglas J Lane, Weirui Chai, Terry L Bowlin

J Antibiot (Tokyo)· September 2019

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Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers.
Nadine G Rouphael, Selwyn J Hurwitz, Mari Hart, Allison Beck, Evan J Anderson, Terry L Bowlin

Antimicrob Agents Chemother· September 2019

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Enantiomeric 4'-Truncated 3-deaza-1',6'-isoneplanocins: Synthesis and antiviral properties including Ebola.
Chong Liu, Rachel Coleman, Ashley Archer, Islam Hussein, Terry L Bowlin

Bioorg Med Chem Lett· September 2019

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Efficacy of Aminomethyl Spectinomycins against Complex Upper Respiratory Tract Bacterial Infections.
Amy Iverson, Christopher J Meyer, Peter Vogel, Samanthi Waidyarachchi, Nisha Das, Terry L Bowlin

Antimicrob Agents Chemother· May 2019

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6'-Fluoro-3-deazaneplanocin: Synthesis and antiviral properties, including Ebola.
Chong Liu, Qi Chen, Steven Cardinale, Terry L Bowlin, Stewart W Schneller

Bioorg Med Chem Lett· December 2018

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