Publications by authors named "Terry Podoll"

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Identification and Characterization of ACP-5862, the Major Circulating Active Metabolite of Acalabrutinib: Both Are Potent and Selective Covalent Bruton Tyrosine Kinase Inhibitors .
Terry Podoll, Paul G Pearson, Allard Kaptein, Jerry Evarts, Gerjan de Bruin

J Pharmacol Exp Ther· January 2023

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Evaluation of the Pharmacokinetics and Safety of a Single Dose of Acalabrutinib in Subjects With Hepatic Impairment.
Yan Xu, Raquel Izumi, Helen Nguyen, Anna Kwan, Howard Kuo, Terry Podoll

J Clin Pharmacol· June 2022

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Pharmacokinetics and Macrophage Inhibitory Cytokine-1 Pharmacodynamics of the Murine Double Minute 2 Inhibitor, Navtemadlin (KRT-232) in Fed and Fasted Healthy Subjects.
Shekman Wong, Cecile Krejsa, Dana Lee, Anna Harris, Emilie Simard, Terry Podoll

Clin Pharmacol Drug Dev· May 2022

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Evaluation of the Drug-Drug Interaction Potential of Acalabrutinib and Its Active Metabolite, ACP-5862, Using a Physiologically-Based Pharmacokinetic Modeling Approach.
Diansong Zhou, Terry Podoll, Yan Xu, Ganesh Moorthy, Karthick Vishwanathan

CPT Pharmacometrics Syst Pharmacol· July 2019

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Oxidative Deamination of Emixustat by Human Vascular Adhesion Protein-1/Semicarbazide-Sensitive Amine Oxidase.
Michael J Reid, Russell Eyre, Terry Podoll

Drug Metab Dispos· May 2019

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Bioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and Humans.
Terry Podoll, Paul G Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova

Drug Metab Dispos· February 2019

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Validation and reproducibility of an LC-MS/MS method for emixustat and its three deaminated metabolites in human plasma.
Terry Podoll, Lisa Geisler, Michael Van Parys, Glenn Hanson, Michael J Reid

Bioanalysis· November 2018

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Bioanalysis of emixustat (ACU-4429) in whole blood collected with volumetric absorptive microsampling by LC-MS/MS.
Zhixin Miao, James G Farnham, Glenn Hanson, Terry Podoll, Michael J Reid

Bioanalysis· June 2016

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Structure based design of an in vivo active hydroxamic acid inhibitor of P. aeruginosa LpxC.
Joseph S Warmus, Cheryl L Quinn, Clarke Taylor, Sean T Murphy, Timothy A Johnson, Terry Podoll

Bioorg Med Chem Lett· April 2012

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In vitro metabolism of clindamycin in human liver and intestinal microsomes.
Michael A Wynalda, J Matthew Hutzler, Michael D Koets, Terry Podoll, Larry C Wienkers

Drug Metab Dispos· July 2003

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