Publications by authors named "Teruki Hamada"

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Xenogenic Engraftment of Human-Induced Pluripotent Stem Cell-Derived Pancreatic Islet Cells in an Immunosuppressive Diabetic Göttingen Mini-Pig Model.
Midori Yamasaki, Toshiyuki Maki, Taisuke Mochida, Teruki Hamada, Saori Watanabe-Matsumoto

Cell Transplant· October 2024

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Design and Identification of a GPR40 Full Agonist () Possessing a 2-Carbamoylphenyl Piperidine Moiety.
Hideki Furukawa, Yasufumi Miyamoto, Yasuhiro Hirata, Koji Watanabe, Yuko Hitomi, Teruki Hamada

J Med Chem· September 2020

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Microminipig: A suitable animal model to estimate oral absorption of sustained-release formulation in humans.
Teruki Hamada, Yukiko Watanabe, Koichi Iida, Noriyasu Sano, Nobuyuki Amano

Int J Pharm· June 2020

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Development of novel highly sensitive methods to detect endogenous cGAMP in cells and tissue.
Shuuichi Miyakawa, Toshitake Okui, Tsubasa Shiraishi, Tomoki Yoshihara, Megumi Hirayama, Teruki Hamada

J Immunol Methods· May 2020

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Direct Drug Delivery of Low-Permeable Compounds to the Central Nervous System Via Intranasal Administration in Rats and Monkeys.
Shinji Iwasaki, Syunsuke Yamamoto, Noriyasu Sano, Kimio Tohyama, Yohei Kosugi, Teruki Hamada

Pharm Res· April 2019

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Design and synthesis of 1-(1-benzothiophen-7-yl)-1H-pyrazole, a novel series of G protein-coupled receptor 52 (GPR52) agonists.
Takashi Nakahata, Kazuyuki Tokumaru, Yoshiteru Ito, Naoki Ishii, Masaki Setoh, Teruki Hamada

Bioorg Med Chem· May 2018

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Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.
Akira Kaieda, Masashi Takahashi, Takafumi Takai, Masayuki Goto, Takahiro Miyazaki, Teruki Hamada

Bioorg Med Chem· February 2018

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Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide to Characterize Its Antiobesity Effects in Diet-Induced Obese Mice.
Shinji Iwasaki, Teruki Hamada, Ikumi Chisaki, Tomohiro Andou, Noriyasu Sano

J Pharmacol Exp Ther· September 2017

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Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action.
Haruyuki Nishida, Yasuyoshi Arikawa, Keizo Hirase, Toshihiro Imaeda, Nobuhiro Inatomi, Teruki Hamada

Bioorg Med Chem· July 2017

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Design, synthesis and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitor.
Ikuo Fujimori, Tomoya Yukawa, Taku Kamei, Yoshihisa Nakada, Nobuki Sakauchi, Teruki Hamada

Bioorg Med Chem· August 2015

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Discovery of the first potent and orally available agonist of the orphan G-protein-coupled receptor 52.
Masaki Setoh, Naoki Ishii, Mitsunori Kono, Yuhei Miyanohana, Eri Shiraishi, Teruki Hamada

J Med Chem· June 2014

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Design, stereoselective synthesis, and biological evaluation of novel tri-cyclic compounds as inhibitor of apoptosis proteins (IAP) antagonists.
Moriteru Asano, Kentaro Hashimoto, Bunnai Saito, Zenyu Shiokawa, Hiroyuki Sumi, Teruki Hamada

Bioorg Med Chem· September 2013

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Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB).
Yasuyoshi Arikawa, Haruyuki Nishida, Osamu Kurasawa, Atsushi Hasuoka, Keizo Hirase, Teruki Hamada

J Med Chem· May 2012

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