Publications by authors named "Teruko Imai"

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Functional Analysis of Modified Caco-2 Cells Carrying CES2A1 as a Model for Intestinal Absorption of Prodrugs.
Teruko Imai, Masanari Isasaka, Yusuke Oyama, Yusuke Takagi, Kayoko Ohura

Biol Pharm Bull· May 2025

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The Association of the Cholesterol Efflux Capacity with the Paraoxonase 1 Q192R Genotype and the Paraoxonase Activity.
Kentaro Oniki, Kayoko Ohura, Megumi Endo, Daniel Akatwijuka, Erika Matsumoto, Teruko Imai

J Atheroscler Thromb· September 2024

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Bioconversion and P-gp-Mediated Transport of Depot Fluphenazine Prodrugs after Intramuscular Injection.
Kayoko Ohura, Yuichiro Nakada, Teruko Imai

J Pharm Sci· July 2023

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Esterases Involved in the Rapid Bioconversion of Esmolol after Intravenous Injection in Humans.
Teruko Imai, Mizuki Isozaki, Kayoko Ohura

Biol Pharm Bull· October 2022

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"Human and Mouse Cross-Reactive" Albumin-Binding Helix-Loop-Helix Peptide Tag for Prolonged Bioactivity of Therapeutic Proteins.
Yuto Nakatani, Zhengmao Ye, Yuki Ishizue, Taishi Higashi, Teruko Imai

Mol Pharm· July 2022

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Improvement of Pharmaceutical Properties of Zerumbone, a Multifunctional Compound, Using Cyclodextrin Derivatives.
Md Mahadi Hassan, Ahmed Fouad Abdelwahab Mohammed, Khaled M Elamin, Hari Prasad Devkota, Yoshitaka Ohno, Teruko Imai

Chem Pharm Bull (Tokyo)· May 2021

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Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys.
Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Teruko Imai

Drug Metab Dispos· March 2020

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Effect of Calcium on the Hydrolysis Activity of Human Butyrylcholinesterase.
Teruko Imai, Fatma Goksin Bahar, Kayoko Ohura, Akihisa Toda

J Pharm Sci· March 2020

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Identification of Major Esterase Involved in Hydrolysis of Soft Anticholinergic (2R3'R-SGM) Designed From Glycopyrrolate in Human and Rat Tissues.
Ahmed Samir, Kayoko Ohura, Nicholas Bodor, Teruko Imai

J Pharm Sci· August 2019

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[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog].
Teruko Imai, Yuichiro Nakada, Kayoko Ohura

Yakugaku Zasshi· June 2019

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Development of simultaneous quantification method of loteprednol etabonate (LE) and its acidic metabolites, and analysis of LE metabolism in rat.
Ahmed Samir, Ayano Kage, Kayoko Ohura, Teruko Imai

Xenobiotica· May 2019

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Receptor-destroying enzyme (RDE) from modulates IgE activity and reduces the initiation of anaphylaxis.
Tatsuya Yamazaki, Masanori Inui, Keiko Hiemori, Susumu Tomono, Makoto Itoh, Teruko Imai

J Biol Chem· April 2019

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[Introducing the Academy of Pharmaceutical Science and Technology, Japan].
Teruko Imai

Yakugaku Zasshi· March 2019

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Analysis of carboxylesterase 2 transcript variants in cynomolgus macaque liver.
Yasuhiro Uno, Yoshiyuki Igawa, Maori Tanaka, Kayoko Ohura, Masakiyo Hosokawa, Teruko Imai

Xenobiotica· February 2019

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Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies.
Yuma Ishizaki, Tomomi Furihata, Yusuke Oyama, Kayoko Ohura, Teruko Imai

Biol Pharm Bull· September 2018

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Molecular characterization and polymorphisms of butyrylcholinesterase in cynomolgus macaques.
Yasuhiro Uno, Shotaro Uehara, Hassan M D Mahadhi, Kayoko Ohura, Masakiyo Hosokawa, Teruko Imai

J Med Primatol· June 2018

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A novel quantification method for serine hydrolases in cellular expression system using fluorophosphonate-biotin probe.
Amira Abdel-Daim, Kayoko Ohura, Teruko Imai

Eur J Pharm Sci· March 2018

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Effect of alcohol on skin permeation and metabolism of an ester-type prodrug in Yucatan micropig skin.
Makiko Fujii, Rieko Ohara, Azusa Matsumi, Kayoko Ohura, Naoya Koizumi, Teruko Imai

Eur J Pharm Sci· November 2017

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Elucidation of the Intestinal Absorption of para-Aminobenzoic Acid, a Marker for Dietary Intake.
Teruko Imai, Keiichiro Tanaka, Takahiro Yonemitsu, Yuta Yakushiji, Kayoko Ohura

J Pharm Sci· September 2017

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Identification of esterase involved in the metabolism of two corticosteroid soft drugs.
Ahmed Samir, Nicholas Bodor, Teruko Imai

Biochem Pharmacol· March 2017

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Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine.
Kayoko Ohura, Hikaru Nishiyama, Saori Saco, Keisuke Kurokawa, Teruko Imai

Drug Metab Dispos· December 2016

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Differences in Intestinal Hydrolytic Activities between Cynomolgus Monkeys and Humans: Evaluation of Substrate Specificities Using Recombinant Carboxylesterase 2 Isozymes.
Yoshiyuki Igawa, Seiya Fujiwara, Kayoko Ohura, Takatsugu Hirokawa, You Nishizawa, Teruko Imai

Mol Pharm· September 2016

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Expression of Carboxylesterase Isozymes and Their Role in the Behavior of a Fexofenadine Prodrug in Rat Skin.
Teruko Imai, Satomi Ariyoshi, Kayoko Ohura, Takashi Sawada, Yuichiro Nakada

J Pharm Sci· February 2016

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Design of Fexofenadine Prodrugs Based on Tissue-Specific Esterase Activity and Their Dissimilar Recognition by P-Glycoprotein.
Kayoko Ohura, Yuichiro Nakada, Shunsuke Kotani, Teruko Imai

J Pharm Sci· September 2015

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Isolation and characterization of arylacetamide deacetylase in cynomolgus macaques.
Yasuhiro Uno, Masakiyo Hosokawa, Teruko Imai

J Vet Med Sci· June 2015

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