Publications by authors named "Tetsuya Okada"

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Activation of XBP1 but not ATF6α rescues heart failure induced by persistent ER stress in medaka fish.
Byungseok Jin, Tokiro Ishikawa, Makoto Kashima, Rei Komura, Hiromi Hirata, Tetsuya Okada

Life Sci Alliance· July 2023

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Proteomic analysis of fatty liver induced by starvation of medaka fish larvae.
Tomoyo Ikeda, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Masaya Ono

Cell Struct Funct· July 2023

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Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice.
Shengyu Jin, Byungseok Jin, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada

Mol Biol Cell· March 2023

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A motor neuron disease-associated mutation produces non-glycosylated Seipin that induces ER stress and apoptosis by inactivating SERCA2b.
Shunsuke Saito, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Kazutoshi Mori

Elife· November 2022

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Drop-Dry Deposition of Ni(OH) Precursors for Fabrication of NiO Thin Films.
Tong Li, Tetsuya Okada, Masaya Ichimura

Materials (Basel)· June 2022

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Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD.
Ginto George, Satoshi Ninagawa, Hirokazu Yagi, Jun-Ichi Furukawa, Noritaka Hashii, Tetsuya Okada

Elife· October 2021

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Endoplasmic Reticulum-Associated Degradation Controls Virus Protein Homeostasis, Which Is Required for Flavivirus Propagation.
Keisuke Tabata, Masashi Arakawa, Kotaro Ishida, Makiko Kobayashi, Atsuki Nara, Tetsuya Okada

J Virol· July 2021

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Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain.
Akira Imamura, Tetsuya Okada, Hikaru Mase, Takuya Otani, Tomoka Kobayashi

Nat Commun· April 2020

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Development of a Rapid in vivo Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish.
Byungseok Jin, Tokiro Ishikawa, Mai Taniguchi, Satoshi Ninagawa, Tetsuya Okada

Cell Struct Funct· February 2020

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EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD.
Ginto George, Satoshi Ninagawa, Hirokazu Yagi, Taiki Saito, Tokiro Ishikawa, Tetsuya Okada

Elife· February 2020

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Reinvestigation of Disulfide-bonded Oligomeric Forms of the Unfolded Protein Response Transducer ATF6.
Hibiki Koba, Shengyu Jin, Nanami Imada, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada

Cell Struct Funct· January 2020

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A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.
Natalia J Martinez, Ganesha Rai, Adam Yasgar, Wendy A Lea, Hongmao Sun, Tetsuya Okada

PLoS One· August 2017

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SEL1L-dependent Substrates Require Derlin2/3 and Herp1/2 for Endoplasmic Reticulum-associated Degradation.
Takehiro Sugimoto, Satoshi Ninagawa, Shimpei Yamano, Tokiro Ishikawa, Tetsuya Okada

Cell Struct Funct· July 2017

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UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage-specific manner.
Tokiro Ishikawa, Takuya Toyama, Yuki Nakamura, Kentaro Tamada, Hitomi Shimizu, Tetsuya Okada

J Cell Biol· June 2017

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Correction: A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.
Natalia J Martinez, Ganesha Rai, Adam Yasgar, Wendy A Lea, Hongmao Sun, Tetsuya Okada

PLoS One· November 2016

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[Mannose trimming mechanism in endoplasmic reticulum-associated degradation of glycoproteins].
Tetsuya Okada, Satoshi Ninagawa, Kazutoshi Mori

Seikagaku· April 2016

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Novel Characteristics of Trypanosoma brucei Guanosine 5'-monophosphate Reductase Distinct from Host Animals.
Tomoaki Bessho, Tetsuya Okada, Chihiro Kimura, Takahiro Shinohara, Ai Tomiyama

PLoS Negl Trop Dis· January 2016

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Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway.
Satoshi Ninagawa, Tetsuya Okada, Yoshiki Sumitomo, Satoshi Horimoto, Takehiro Sugimoto

J Cell Biol· November 2015

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Lipocalin-type prostaglandin D synthase scavenges biliverdin in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.
Takashi Inui, Mitsuhito Mase, Ryoko Shirota, Mariko Nagashima, Tetsuya Okada

J Cereb Blood Flow Metab· September 2014

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EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step.
Satoshi Ninagawa, Tetsuya Okada, Yoshiki Sumitomo, Yukiko Kamiya, Koichi Kato

J Cell Biol· August 2014

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The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation.
Riwa Ozasa, Tetsuya Okada, Satomi Nadanaka, Takahiko Nagamine, Alisha Zyryanova

Cell Struct Funct· April 2014

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The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein.
Satoshi Horimoto, Satoshi Ninagawa, Tetsuya Okada, Hibiki Koba, Takehiro Sugimoto

J Biol Chem· November 2013

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ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish.
Tokiro Ishikawa, Tetsuya Okada, Tomoko Ishikawa-Fujiwara, Takeshi Todo, Yasuhiro Kamei

Mol Biol Cell· May 2013

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A thrombospondin-dependent pathway for a protective ER stress response.
Jeffrey M Lynch, Marjorie Maillet, Davy Vanhoutte, Aryn Schloemer, Michelle A Sargent, Tetsuya Okada

Cell· June 2012

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An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy.
Padmaja Gade, Girish Ramachandran, Uday B Maachani, Mark A Rizzo, Tetsuya Okada

Proc Natl Acad Sci U S A· June 2012

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