Publications by authors named "Thomas Broekelmann"

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Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2).
Nicholas K Bodmer, Russell H Knutsen, Robyn A Roth, Ryan M Castile, Michael D Brodt, Thomas J Broekelmann

Dev Dyn· February 2024

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Targeting Epidermal Growth Factor Receptor to Stimulate Elastic Matrix Regenerative Repair.
Simran Dayal, Thomas Broekelmann, Robert P Mecham, Anand Ramamurthi

Tissue Eng Part A· April 2023

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The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome.
Conor McClenaghan, Yan Huang, Scot J Matkovich, Attila Kovacs, Carla J Weinheimer, Thomas J Broekelmann

Function (Oxf)· January 2023

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Deletion of type VIII collagen reduces blood pressure, increases carotid artery functional distensibility and promotes elastin deposition.
Amanda L Mohabeer, Jeffrey T Kroetsch, Meghan McFadden, Negin Khosraviani, Thomas J Broekelmann

Matrix Biol Plus· December 2021

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Identification of the growth factor-binding sequence in the extracellular matrix protein MAGP-1.
Thomas J Broekelmann, Nicholas K Bodmer, Robert P Mecham

J Biol Chem· February 2020

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Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress.
Vivian S Lee, Carmen M Halabi, Thomas J Broekelmann, Philip C Trackman, Nathan O Stitziel

JCI Insight· June 2019

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Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis.
Li-Hao Huang, Bernd H Zinselmeyer, Chih-Hao Chang, Brian T Saunders, Andrew Elvington, Thomas J Broekelmann

Cell Metab· February 2019

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Measurement of elastin, collagen, and total protein levels in tissues.
Ivan Stoilov, Barry C Starcher, Robert P Mecham, Thomas J Broekelmann

Methods Cell Biol· November 2018

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Microfibril-associated glycoproteins MAGP-1 and MAGP-2 in disease.
Clarissa S Craft, Thomas J Broekelmann, Robert P Mecham

Matrix Biol· October 2018

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Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells.
Michael D Onken, Carol M Makepeace, Kevin M Kaltenbronn, Stanley M Kanai, Tyson D Todd, Thomas J Broekelmann

Sci Signal· September 2018

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Minoxidil improves vascular compliance, restores cerebral blood flow, and alters extracellular matrix gene expression in a model of chronic vascular stiffness.
Russell H Knutsen, Scott C Beeman, Thomas J Broekelmann, Delong Liu, Kit Man Tsang

Am J Physiol Heart Circ Physiol· July 2018

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Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries.
Carmen M Halabi, Thomas J Broekelmann, Michelle Lin, Vivian S Lee, Mon-Li Chu

Sci Adv· May 2017

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Chronic antihypertensive treatment improves pulse pressure but not large artery mechanics in a mouse model of congenital vascular stiffness.
Carmen M Halabi, Thomas J Broekelmann, Russell H Knutsen, Li Ye, Robert P Mecham

Am J Physiol Heart Circ Physiol· September 2015

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Microfibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivo.
Michelle D Combs, Russell H Knutsen, Thomas J Broekelmann, Holly M Toennies, Thomas J Brett

J Biol Chem· October 2013

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Zap70 inhibits Syk-mediated osteoclast function.
Wei Zou, Monica Croke, Tomohiro Fukunaga, Thomas J Broekelmann, Robert P Mecham

J Cell Biochem· August 2013

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Type I phosphotidylinosotol 4-phosphate 5-kinase γ regulates osteoclasts in a bifunctional manner.
Tingting Zhu, Jean C Chappel, Fong-Fu Hsu, John Turk, Rajeev Aurora, Thomas J Broekelmann

J Biol Chem· February 2013

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Paxillin contracts the osteoclast cytoskeleton.
Wei Zou, Carl J Deselm, Thomas J Broekelmann, Robert P Mecham, Scott Vande Pol

J Bone Miner Res· December 2012

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Cardiac specific ATP-sensitive K+ channel (KATP) overexpression results in embryonic lethality.
Amir Toib, Hai Xia Zhang, Thomas J Broekelmann, Krzysztof L Hyrc, Qiusha Guo

J Mol Cell Cardiol· September 2012

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Alternative splicing and tissue-specific elastin misassembly act as biological modifiers of human elastin gene frameshift mutations associated with dominant cutis laxa.
Hideki Sugitani, Eiichi Hirano, Russell H Knutsen, Adrian Shifren, Jessica E Wagenseil, Thomas J Broekelmann

J Biol Chem· June 2012

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Oophorectomy-induced bone loss is attenuated in MAGP1-deficient mice.
Clarissa S Craft, Thomas J Broekelmann, Wei Zou, Jean C Chappel, Steven L Teitelbaum

J Cell Biochem· January 2012

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Genetic modifiers of cardiovascular phenotype caused by elastin haploinsufficiency act by extrinsic noncomplementation.
Beth A Kozel, Russell H Knutsen, Li Ye, Christopher H Ciliberto, Thomas J Broekelmann

J Biol Chem· December 2011

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Oxidative modifications of the C-terminal domain of tropoelastin prevent cell binding.
Kamal Akhtar, Thomas J Broekelmann, Haowei Song, John Turk, Tom J Brett

J Biol Chem· April 2011

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Oxidative and nitrosative modifications of tropoelastin prevent elastic fiber assembly in vitro.
Kamal Akhtar, Thomas J Broekelmann, Ming Miao, Fred W Keeley, Barry C Starcher

J Biol Chem· November 2010

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Cytoskeletal dysfunction dominates in DAP12-deficient osteoclasts.
Wei Zou, Tingting Zhu, Clarissa S Craft, Thomas J Broekelmann, Robert P Mecham

J Cell Sci· September 2010

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Microfibril-associated glycoprotein-1, an extracellular matrix regulator of bone remodeling.
Clarissa S Craft, Wei Zou, Marcus Watkins, Susan Grimston, Michael D Brodt, Thomas J Broekelmann

J Biol Chem· July 2010

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