Publications by authors named "Thomas Buch"

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The Histone Deacetylase Inhibitor Entinostat Mediates HER2 Downregulation in Gastric Cancer, Providing the Basis for Its Particular Efficacy in HER2-Amplified Tumors and in Combination Therapies.
Tamara Zenz, Robert Jenke, René Thieme, Tim Kahl, Hannes Borchardt

Cancer Res Treat· July 2025

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Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat.
Tamara Zenz, Robert Jenke, Denys Oliinyk, Sandra Noske, René Thieme

Neoplasia· February 2025

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Vorinostat Treatment of Gastric Cancer Cells Leads to ROS-Induced Cell Inhibition and a Complex Pattern of Molecular Alterations in Nrf2-Dependent Genes.
Leoni Lorenz, Tamara Zenz, Denys Oliinyk, Florian Meier-Rosar, Robert Jenke

Pharmaceuticals (Basel)· August 2024

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HDAC inhibitors activate lipid peroxidation and ferroptosis in gastric cancer.
Robert Jenke, Denys Oliinyk, Tamara Zenz, Justus Körfer, Linda Schäker-Hübner

Biochem Pharmacol· July 2024

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Balancing Histone Deacetylase (HDAC) Inhibition and Drug-likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors.
Linda Schäker-Hübner, Reza Haschemi, Thomas Büch, Fabian B Kraft, Birke Brumme

ChemMedChem· May 2022

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Tyrosine-modified linear PEIs for highly efficacious and biocompatible siRNA delivery in vitro and in vivo.
Michael Karimov, Marion Schulz, Tim Kahl, Sandra Noske, Malgorzata Kubczak

Nanomedicine· August 2021

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Nrf2/Keap1-Pathway Activation and Reduced Susceptibility to Chemotherapy Treatment by Acidification in Esophageal Adenocarcinoma Cells.
Lucie Storz, Philipp Walther, Olga Chemnitzer, Orestis Lyros, Stefan Niebisch

Cancers (Basel)· June 2021

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Anticancer Therapy with HDAC Inhibitors: Mechanism-Based Combination Strategies and Future Perspectives.
Robert Jenke, Nina Reßing, Finn K Hansen, Achim Aigner, Thomas Büch

Cancers (Basel)· February 2021

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Inhibition of HER Receptors Reveals Distinct Mechanisms of Compensatory Upregulation of Other HER Family Members: Basis for Acquired Resistance and for Combination Therapy.
Daniela Gutsch, Robert Jenke, Thomas Büch, Achim Aigner

Cells· January 2021

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SATB1-Mediated Upregulation of the Oncogenic Receptor Tyrosine Kinase HER3 Antagonizes MET Inhibition in Gastric Cancer Cells.
Robert Jenke, Miriam Holzhäuser-Rein, Stefanie Mueller-Wilke, Florian Lordick, Achim Aigner

Int J Mol Sci· December 2020

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Restoration of MARCKS enhances chemosensitivity in cancer.
Tim Wenzel, Thomas Büch, Nicole Urban, Ulrike Weirauch, Katrin Schierle

J Cancer Res Clin Oncol· April 2020

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Correction to: Restoration of MARCKS enhances chemosensitivity in cancer.
Tim Wenzel, Thomas Büch, Nicole Urban, Ulrike Weirauch, Katrin Schierle

J Cancer Res Clin Oncol· April 2020

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Extracellular vesicle (ECV)-modified polyethylenimine (PEI) complexes for enhanced siRNA delivery in vitro and in vivo.
Petro Zhupanyn, Alexander Ewe, Thomas Büch, Anastasia Malek, Phil Rademacher

J Control Release· March 2020

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Role of Chemosensory TRP Channels in Lung Cancer.
Thomas R H Büch, Eva A M Büch, Ingrid Boekhoff, Dirk Steinritz, Achim Aigner

Pharmaceuticals (Basel)· September 2018

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Incidents between Straight-ahead Cyclists and Right-turning Motor Vehicles at Signalised Junctions.
Thomas Skallebæk Buch, Søren Underlien Jensen

Accid Anal Prev· August 2017

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Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents.
Bernhard Stenger, Franziska Zehfuss, Harald Mückter, Annette Schmidt, Frank Balszuweit

Arch Toxicol· September 2015

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Chemosensory TRP channels in the respiratory tract: role in toxic lung injury and potential as "sweet spots" for targeted therapies.
Thomas Büch, Eva Schäfer, Dirk Steinritz, Alexander Dietrich, Thomas Gudermann

Rev Physiol Biochem Pharmacol· February 2014

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TSH induces metallothionein 1 in thyrocytes via Gq/11- and PKC-dependent signaling.
Christer M Bäck, Stefanie Stohr, Eva A M Schäfer, Heike Biebermann, Ingrid Boekhoff

J Mol Endocrinol· January 2014

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Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells.
Thomas Robert Heinrich Büch, Eva Anna Maria Schäfer, Maria-Theresia Demmel, Ingrid Boekhoff, Horst Thiermann

Chem Biol Interact· December 2013

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Alternative G protein coupling and biased agonism: new insights into melanocortin-4 receptor signalling.
Andreas Breit, Thomas R H Büch, Ingrid Boekhoff, Hans Jürgen Solinski, Ellen Damm

Mol Cell Endocrinol· January 2011

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NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells.
Alexander Köenig, Thomas Linhart, Katrin Schlengemann, Kristina Reutlinger, Jessica Wegele

Gastroenterology· March 2010

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Critical role of G(alpha)12 and G(alpha)13 for human small cell lung cancer cell proliferation in vitro and tumor growth in vivo.
Marius Grzelinski, Olaf Pinkenburg, Thomas Büch, Maike Gold, Stefanie Stohr

Clin Cancer Res· March 2010

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Pertussis toxin-sensitive signaling of melanocortin-4 receptors in hypothalamic GT1-7 cells defines agouti-related protein as a biased agonist.
Thomas R H Büch, Dominik Heling, Ellen Damm, Thomas Gudermann, Andreas Breit

J Biol Chem· September 2009

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G13-dependent activation of MAPK by thyrotropin.
Thomas R H Büch, Heike Biebermann, Hermann Kalwa, Olaf Pinkenburg, Denise Hager

J Biol Chem· July 2008

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Vasa vasorum and atherosclerosis - Quid novi?
Alexander C Langheinrich, Marian Kampschulte, Thomas Buch, Rainer M Bohle

Thromb Haemost· June 2007

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