Publications by authors named "Thomas Elebring"

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What is the most important approach in current drug discovery: doing the right things or doing things right?
Thomas Elebring, Adrian Gill, Alleyn T Plowright

Drug Discov Today· November 2012

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Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules.
Tim Luker, Lilian Alcaraz, Kamaldeep K Chohan, Niklas Blomberg, Dearg S Brown, Thomas Elebring

Bioorg Med Chem Lett· October 2011

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(R)-(3-amino-2-fluoropropyl) phosphinic acid (AZD3355), a novel GABAB receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action.
Anders Lehmann, Madeleine Antonsson, Ann Aurell Holmberg, L Ashley Blackshaw, Lena Brändén, Thomas Elebring

J Pharmacol Exp Ther· November 2009

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Making medicinal chemistry more effective--application of Lean Sigma to improve processes, speed and quality.
Shalini Andersson, Alan Armstrong, Annika Björe, Sue Bowker, Steve Chapman, Thomas Elebring

Drug Discov Today· June 2009

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Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.
Christer Alstermark, Kosrat Amin, Sean R Dinn, Thomas Elebring, Ola Fjellström

J Med Chem· July 2008

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Scaffold hopping, synthesis and structure-activity relationships of 5,6-diaryl-pyrazine-2-amide derivatives: a novel series of CB1 receptor antagonists.
Jonas Boström, Kristina Berggren, Thomas Elebring, Peter J Greasley, Michael Wilstermann

Bioorg Med Chem· June 2007

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Effects of (2R)-(3-amino-2-fluoropropyl)sulphinic acid (AFPSiA) on transient lower oesophageal sphincter relaxation in dogs and mechanism of hypothermic effects in mice.
Anders Lehmann, Ann Aurell Holmberg, Ulhas Bhatt, Marianne Bremner-Danielsen, Lena Brändén, Thomas Elebring

Br J Pharmacol· September 2005

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Identification and characterisation of a novel splice variant of the human CB1 receptor.
Erik Ryberg, Huy Khang Vu, Niklas Larsson, Thierry Groblewski, Stephan Hjorth, Thomas Elebring

FEBS Lett· January 2005

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Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 1.
Thomas C Kühler, Marianne Swanson, Beritte Christenson, Ann-Charlotte Klintenberg, Bo Lamm, Thomas Elebring

J Med Chem· September 2002

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