Publications by authors named "Thomas Friedberg"

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In silico platform for xenobiotics ADME-T pharmacological properties modeling and prediction. Part I: Beyond the reduction of animal model use.
Lucie Huynh, Rosalinde Masereeuw, Thomas Friedberg, Magnus Ingelman-Sundberg, Philippe Manivet

Drug Discov Today· April 2009

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Establishment of functional human cytochrome P450 monooxygenase systems in Escherichia coli.
Michael P Pritchard, Lesley McLaughlin, Thomas Friedberg

Methods Mol Biol· June 2006

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Proteasomal degradation of human CYP1B1: effect of the Asn453Ser polymorphism on the post-translational regulation of CYP1B1 expression.
Silvio Bandiera, Simone Weidlich, Volker Harth, Peter Broede, Yun Ko, Thomas Friedberg

Mol Pharmacol· February 2005

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AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line.
Franck Rencurel, Alasdair Stenhouse, Simon A Hawley, Thomas Friedberg, D Grahame Hardie

J Biol Chem· February 2005

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Directional trans-epithelial transport of organic anions in porcine LLC-PK1 cells that co-express human OATP1B1 (OATP-C) and MRP2.
Kevin J Spears, Jillian Ross, Alasdair Stenhouse, Clive J Ward, Lay-Beng Goh, Thomas H Friedberg

Biochem Pharmacol· February 2005

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Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: contribution of drug transport proteins.
Jeffrey Cummings, Noam Zelcer, John D Allen, Denggao Yao, Gary Boyd, Thomas H Friedberg

Biochem Pharmacol· January 2004

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In vitro metabolism of genistein and tangeretin by human and murine cytochrome P450s.
Vibeke M Breinholt, Salka E Rasmussen, Kim Brøsen, Thomas H Friedberg

Pharmacol Toxicol· July 2003

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An amperometric biosensor with human CYP3A4 as a novel drug screening tool.
Shiba Joseph, James F Rusling, Yuri M Lvov, Thomas Friedberg, Uwe Fuhr

Biochem Pharmacol· June 2003

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Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man.
Lay Beng Goh, Kevin J Spears, Denggao Yao, Andy Ayrton, Paul Morgan, Thomas Friedberg

Biochem Pharmacol· December 2002

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The N-demethylation of the doxepin isomers is mainly catalyzed by the polymorphic CYP2C19.
Sebastian Härtter, Gunnel Tybring, Thomas Friedberg, Harald Weigmann, Christoph Hiemke

Pharm Res· July 2002

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CYP3A4 active site volume modification by mutagenesis of leucine 211.
Stephen M Fowler, John M Taylor, Thomas Friedberg, C Roland Wolf, Robert J Riley

Drug Metab Dispos· April 2002

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