Publications by authors named "Thomas G Osimitz"

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Mode of action analysis for mouse liver tumor formation by MGK-264 and human relevance.
Junji Yano, Kensuke Kawamoto, Yukako Shimotsuma, Keiko Ogata, Kohei Matsunaga, Thomas G Osimitz

Regul Toxicol Pharmacol· December 2025

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Mode of action analysis for rat thyroid gland follicular cell tumor formation by MGK-264 and human relevance.
Junji Yano, Kensuke Kawamoto, Yukako Shimotsuma, Kohei Matsunaga, Jun Abe, Thomas G Osimitz

Regul Toxicol Pharmacol· August 2025

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Evaluation of potential toxicity of smoke from controlled burns of furnished rooms - effect of flame retardancy.
Thomas G Osimitz, Wiebke Droege, Giel Hendriks, Matthew S Blais

J Toxicol Environ Health A· October 2022

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Perspectives on interpretation of Rivera-González et al., (2021).
Thomas G Osimitz, Wiebke Droege

Chemosphere· February 2022

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Kinetics of metabolism of deltamethrin and - and -permethrin . Studies using rat and human liver microsomes, isolated rat hepatocytes and rat liver cytosol.
Roger J Price, Mary P Scott, Carina Cantrill, Larry G Higgins, Marjory Moreau, Thomas G Osimitz

Xenobiotica· January 2021

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Metabolism of bifenthrin, β-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes.
Laura Hedges, Susan Brown, A Kenneth MacLeod, Marjory Moreau, Miyoung Yoon, Thomas G Osimitz

Xenobiotica· December 2020

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Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats.
Larry G Higgins, Lynsey R Chatham, Sara L Tomczynski, A Kenneth MacLeod, Marjory Moreau, Thomas G Osimitz

Toxicology· October 2020

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Comment on "Concentrations of Brominated Flame Retardants in Indoor Air and Dust from Ireland Reveal Elevated Exposure to Decabromodiphenyl Ethane".
Thomas G Osimitz, Matthew Blais, A Wallace Hayes, Sam Kacew, Wiebke Droege

Environ Sci Technol· September 2020

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Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids.
Pankajini Mallick, Gina Song, Alina Y Efremenko, Salil N Pendse, Moire R Creek, Thomas G Osimitz

Toxicol Sci· August 2020

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Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance.
Brian G Lake, Roger J Price, Mary P Scott, Lynsey R Chatham, Audrey Vardy, Thomas G Osimitz

Toxicology· June 2020

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An Evaluation of the Human Relevance of the Liver Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action.
Miwa Kondo, Hiroko Kikumoto, Thomas G Osimitz, Samuel M Cohen, Brian G Lake

Toxicol Sci· May 2020

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Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans.
Pankajini Mallick, Marjory Moreau, Gina Song, Alina Y Efremenko, Salil N Pendse, Thomas G Osimitz

Toxicol Sci· January 2020

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Assess flame retardants with care.
Thomas G Osimitz, Sam Kacew, A Wallace Hayes

Science· September 2019

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Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation.
Gina Song, Marjory Moreau, Alina Efremenko, Brian G Lake, Huali Wu, Thomas G Osimitz

Toxicol Sci· June 2019

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Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes.
Laura Hedges, Susan Brown, A Kenneth MacLeod, Audrey Vardy, Edward Doyle, Thomas G Osimitz

Xenobiotica· May 2019

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Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations.
Laura Hedges, Susan Brown, Audrey Vardy, Edward Doyle, Miyoung Yoon, Thomas G Osimitz

Xenobiotica· April 2019

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Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse.
Miwa Kondo, Kaori Miyata, Hirohisa Nagahori, Kayo Sumida, Thomas G Osimitz

Toxicol Sci· April 2019

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Exploring the science, safety, and benefits of air care products: perspectives from the inaugural air care summit.
Mary B Johnson, Rick Kingston, Mark J Utell, J R Wells, Madhuri Singal, Thomas G Osimitz

Inhal Toxicol· January 2019

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Safety assessment of the use of Bacillus-based cleaning products.
Ninna W Berg, Matthew R Evans, John Sedivy, Robert Testman, Kimon Acedo, Thomas G Osimitz

Food Chem Toxicol· June 2018

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An Evaluation of the Human Relevance of the Lung Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action.
Tomoya Yamada, Miwa Kondo, Kaori Miyata, Keiko Ogata, Masahiko Kushida, Thomas G Osimitz

Toxicol Sci· June 2017

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Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages.
Gina Song, Xueying Sun, Ronald N Hines, D Gail McCarver, Brian G Lake, Thomas G Osimitz

Drug Metab Dispos· May 2017

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Subchronic toxicology of tetrabromobisphenol A in rats.
Thomas G Osimitz, Wiebke Droege, A Wallace Hayes

Hum Exp Toxicol· November 2016

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Mode of action analysis for pesticide-induced rodent liver tumours involving activation of the constitutive androstane receptor: relevance to human cancer risk.
Brian G Lake, Roger J Price, Thomas G Osimitz

Pest Manag Sci· June 2015

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Polyester monomers lack ability to bind and activate both androgenic and estrogenic receptors as determined by in vitro and in silico methods.
Thomas G Osimitz, William J Welsh, Ni Ai, Colleen Toole

Food Chem Toxicol· January 2015

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Crystallographic analysis and mimicking of estradiol binding: interpretation and speculation.
Thomas G Osimitz, Michael L Dourson, A Wallace Hayes, Sam Kacew

Environ Health Perspect· April 2014

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