Publications by authors named "Thomas Goldner"

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Discovery of AIC263282, a Hepatitis B Virus Capsid Assembly Modulator Ready for Candidate Profiling.
Bernhard Lesch, Alexander Birkmann, Susanne Bonsmann, Alastair Donald, Florian Engel, Thomas Goldner

J Med Chem· March 2025

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Structure-based Design of Novel Hepatitis B Virus Capsid Assembly Modulators.
Elena Detta, Angelica Corcuera, Andreas Urban, Thomas Goldner, Susanne Bonsmann

Bioorg Med Chem Lett· September 2023

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An automated microfluidic platform for the screening and characterization of novel hepatitis B virus capsid assembly modulators.
Tamás Vermes, Mark Kielpinski, Thomas Henkel, Miquel A Pericàs, Esther Alza, Thomas Goldner

Anal Methods· January 2022

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Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis.
Debra C Quenelle, Alexander Birkmann, Thomas Goldner, Tamara Pfaff, Holger Zimmermann

Antiviral Res· January 2018

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Mutual Interplay between the Human Cytomegalovirus Terminase Subunits pUL51, pUL56, and pUL89 Promotes Terminase Complex Formation.
Sebastian Neuber, Karen Wagner, Thomas Goldner, Peter Lischka, Lars Steinbrueck

J Virol· June 2017

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No Evidence of Pritelivir Resistance Among Herpes Simplex Virus Type 2 Isolates After 4 Weeks of Daily Therapy.
Paul T Edlefsen, Alexander Birkmann, Meei-Li Huang, Craig A Magaret, Jia Jin Kee, Thomas Goldner

J Infect Dis· July 2016

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Phenotypic characterization of two naturally occurring human Cytomegalovirus sequence polymorphisms located in a distinct region of ORF UL56 known to be involved in in vitro resistance to letermovir.
Thomas Goldner, Holger Zimmermann, Peter Lischka

Antiviral Res· April 2015

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Geno- and phenotypic characterization of human cytomegalovirus mutants selected in vitro after letermovir (AIC246) exposure.
Thomas Goldner, Christine Hempel, Helga Ruebsamen-Schaeff, Holger Zimmermann, Peter Lischka

Antimicrob Agents Chemother· September 2014

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Pharmacokinetics-pharmacodynamics of the helicase-primase inhibitor pritelivir following treatment of wild-type or pritelivir-resistant virus infection in a murine herpes simplex virus 1 infection model.
Subhajit Biswas, Soumi Sukla, Thomas Goldner, Hugh J Field, Dirk Kropeit

Antimicrob Agents Chemother· July 2014

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The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase.
Thomas Goldner, Guy Hewlett, Nicole Ettischer, Helga Ruebsamen-Schaeff, Holger Zimmermann

J Virol· October 2011

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In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246.
Peter Lischka, Guy Hewlett, Tobias Wunberg, Judith Baumeister, Daniela Paulsen, Thomas Goldner

Antimicrob Agents Chemother· March 2010

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