Publications by authors named "Thomas Hudzik"

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Safety and Tolerability of Single and Multiple Daily Oral Doses of Dried Kratom Leaf Powder in a Randomized Trial in Healthy Volunteers.
Marilyn A Huestis, John Bothmer, Thomas Hudzik, Jack E Henningfield, Sibyl Swift

Ther Drug Monit· January 2026

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Cannabis and sport: A World Anti-Doping perspective.
Thomas J Hudzik, Marilyn A Huestis, Sabina Strano Rossi, Yorck-Olaf Schumacher, Peter Harcourt

Addiction· November 2023

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Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Na1.7/ Nav1.8 blockers for the treatment of pain.
Meena V Patel, Hillary M Peltier, Mark A Matulenko, John R Koenig, Marc J C Scanio, Thomas Hudzik

Bioorg Med Chem· June 2022

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Improving Translational Research Outcomes for Opioid Use Disorder Treatments.
Jermaine D Jones, Neil B Varshneya, Thomas J Hudzik, Andrew S Huhn

Curr Addict Rep· March 2021

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β -Adrenoceptor agonist activity of higenamine.
Thomas J Hudzik, Metul Patel, Andrew Brown

Drug Test Anal· February 2021

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β-Phenylethylamine and various monomethylated and para-halogenated analogs. Acute toxicity studies in mice.
Aron D Mosnaim, Marion E Wolf, James J Iii O'Donnell, Thomas Hudzik

Drug Chem Toxicol· July 2020

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Abuse liability assessment for biologic drugs - All molecules are not created equal.
Christina L Zuch de Zafra, Carrie G Markgraf, David R Compton, Thomas J Hudzik

Regul Toxicol Pharmacol· February 2018

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Preclinical abuse liability assessment of ABT-126, an agonist at the α7 nicotinic acetylcholine receptor (nAChR).
Thomas J Hudzik, Ana M Basso, James J Lynch, William M Bracken, Eric G Mohler

Pharmacol Biochem Behav· July 2017

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Behavioral effects of β-phenylethylamine and various monomethylated and monohalogenated analogs in mice are mediated by catecholaminergic mechanisms.
Aron D Mosnaim, Thomas Hudzik, Marion E Wolf

Am J Ther· September 2016

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Drug Tolerance: A Known Unknown in Translational Neuroscience.
Anton Bespalov, Reinhold Müller, Ana-Lucia Relo, Thomas Hudzik

Trends Pharmacol Sci· May 2016

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The Utility of Impulsive Bias and Altered Decision Making as Predictors of Drug Efficacy and Target Selection: Rethinking Behavioral Screening for Antidepressant Drugs.
Gerard J Marek, Mark Day, Thomas J Hudzik

J Pharmacol Exp Ther· March 2016

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A randomized, placebo-controlled pilot trial of the delta opioid receptor agonist AZD2327 in anxious depression.
Erica M Richards, Daniel C Mathews, David A Luckenbaugh, Dawn F Ionescu, Rodrigo Machado-Vieira, Thomas Hudzik

Psychopharmacology (Berl)· March 2016

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A retrospective evaluation of species-specific sensitivity for neurological signs in toxicological studies: Is the dog more sensitive than the non-human primate?
Kathrin Backes, Helga Lorenz, Loic Laplanche, Thomas J Hudzik, Heidrun Potschka

Toxicol Lett· January 2016

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Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward.
Ruth A Roberts, Michael Aschner, David Calligaro, Tomas R Guilarte, Joseph P Hanig, Thomas J Hudzik

Toxicol Sci· December 2015

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Analgesic effects of β-phenylethylamine and various methylated derivatives in mice.
Aron D Mosnaim, Thomas Hudzik, Marion E Wolf

Neurochem Res· September 2014

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Assessment of the abuse liability of ABT-288, a novel histamine H₃ receptor antagonist.
Thomas J Hudzik, Ana Basso, Janel M Boyce-Rustay, William Bracken, Kaitlin E Browman

Psychopharmacology (Berl)· July 2013

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Rat brain-uptake index for phenylethylamine and various monomethylated derivatives.
Aron D Mosnaim, Owen H Callaghan, Thomas Hudzik, Marion E Wolf

Neurochem Res· April 2013

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4-Piperidin-4-ylidenemethyl-benzamides as δ-opioid receptor agonists for CNS indications: identifying clinical candidates.
Cathy L Dantzman, Megan M King, Glen E Ernst, Xia Wang, John P McCauley, Thomas J Hudzik

Bioorg Med Chem Lett· January 2012

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Multiparameter exploration of piperazine derivatives as δ-opioid receptor agonists for CNS indications.
John P McCauley, Cathy L Dantzman, Megan M King, Glen E Ernst, Xia Wang, Thomas J Hudzik

Bioorg Med Chem Lett· January 2012

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Acute nicotine and phencyclidine increase locomotor activity of the guinea pig with attenuated potencies relative to their effects on rat or mouse.
Mark A Simmons, Jennifer L Werkheiser, Thomas J Hudzik

Pharmacol Biochem Behav· January 2010

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Mechanistic investigation of N,N-diethyl-4-(phenyl-piperidin-4-ylidenemethyl)-benzamide-induced insulin depletion in the rat and RINm5F cells.
Monicah A Otieno, Nicole Bavuso, Joseph Milano, Linda Foster-Brown, Khanh-Hui Bui, Thomas Hudzik

Toxicol Sci· September 2008

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Synthesis of novel quinolone and quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amides: a late-stage diversification approach to potent 5HT1B antagonists.
Carey L Horchler, John P McCauley, James E Hall, Dean H Snyder, W Craig Moore, Thomas J Hudzik

Bioorg Med Chem· January 2007

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