Publications by authors named "Thomas Ort"

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In-line circular dichroism and fluorescence for real-time monitoring of monoclonal antibody structure during affinity chromatography.
Charles Moore-Kelly, Alison Rodger, Tim R Dafforn, Owen R T Thomas

J Chromatogr A· August 2025

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Analysis of the Structure of 14 Therapeutic Antibodies Using Circular Dichroism Spectroscopy.
Maria G Bruque, Alison Rodger, Søren Vrønning Hoffmann, Nykola C Jones, Jean Aucamp

Anal Chem· September 2024

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Integrated system for temperature-controlled fast protein liquid chromatography. IV. Continuous 'one-column' 'low-salt' hydrophobic interaction chromatography.
Alexander Brean, Tim W Overton, Daniel G Bracewell, Matthias Franzreb, Owen R T Thomas

J Chromatogr A· August 2024

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Probing fibronectin adsorption on chemically defined surfaces by means of single molecule force microscopy.
Evangelos Liamas, Richard A Black, Paul A Mulheran, Robert Tampé, Ralph Wieneke

Sci Rep· September 2020

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Tribocorrosion behaviour of pure titanium in bovine serum albumin solution: A multiscale study.
Evangelos Liamas, Owen R T Thomas, Anna Igual Muñoz, Zhenyu J Zhang

J Mech Behav Biomed Mater· February 2020

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Integrated system for temperature-controlled fast protein liquid chromatography. III. Continuous downstream processing of monoclonal antibodies.
Benedikt Ketterer, Charles Moore-Kelly, Owen R T Thomas, Matthias Franzreb

J Chromatogr A· January 2020

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Automated High-Throughput Capillary Circular Dichroism and Intrinsic Fluorescence Spectroscopy for Rapid Determination of Protein Structure.
Charles Moore-Kelly, John Welsh, Alison Rodger, Tim R Dafforn, Owen R T Thomas

Anal Chem· November 2019

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Effect of the electrochemical characteristics of titanium on the adsorption kinetics of albumin.
Evangelos Liamas, Owen R T Thomas, Anna Igual Muñoz, Zhenyu J Zhang

RSC Adv· October 2019

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Improving the Numerical Stability of the NAST Force Field for RNA Simulations.
Nils P Petersen, Thomas Ort, Andrew E Torda

J Chem Theory Comput· May 2019

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Use of a design of experiments approach to optimise production of a recombinant antibody fragment in the periplasm of Escherichia coli: selection of signal peptide and optimal growth conditions.
Ikhlaas M Kasli, Owen R T Thomas, Tim W Overton

AMB Express· January 2019

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Development of a simple intensified fermentation strategy for growth of Magnetospirillum gryphiswaldense MSR-1: Physiological responses to changing environmental conditions.
Alfred Fernández-Castané, Hong Li, Owen R T Thomas, Tim W Overton

N Biotechnol· November 2018

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Adsorption of Fibronectin Fragment on Surfaces Using Fully Atomistic Molecular Dynamics Simulations.
Evangelos Liamas, Karina Kubiak-Ossowska, Richard A Black, Owen R T Thomas, Zhenyu J Zhang

Int J Mol Sci· October 2018

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Flow cytometry as a rapid analytical tool to determine physiological responses to changing O and iron concentration by Magnetospirillum gryphiswaldense strain MSR-1.
Alfred Fernández-Castané, Hong Li, Owen R T Thomas, Tim W Overton

Sci Rep· October 2017

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Integrated system for temperature-controlled fast protein liquid chromatography. II. Optimized adsorbents and 'single column continuous operation'.
Ping Cao, Tobias K H Müller, Benedikt Ketterer, Stephanie Ewert, Eirini Theodosiou

J Chromatogr A· July 2015

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Continuous protein purification using functionalized magnetic nanoparticles in aqueous micellar two-phase systems.
Ingo Fischer, Chia-Chang Hsu, Markus Gärtner, Christine Müller, Tim W Overton

J Chromatogr A· August 2013

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Multi-cycle recovery of lactoferrin and lactoperoxidase from crude whey using fimbriated high-capacity magnetic cation exchangers and a novel "rotor-stator" high-gradient magnetic separator.
Geoffrey N Brown, Christine Müller, Eirini Theodosiou, Matthias Franzreb, Owen R T Thomas

Biotechnol Bioeng· June 2013

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Integrated system for temperature-controlled fast protein liquid chromatography comprising improved copolymer modified beaded agarose adsorbents and a travelling cooling zone reactor arrangement.
Tobias K H Müller, Ping Cao, Stephanie Ewert, Jonas Wohlgemuth, Haiyang Liu

J Chromatogr A· April 2013

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Surfactant-free purification of membrane proteins with intact native membrane environment.
Mohammed Jamshad, Yu-Pin Lin, Timothy J Knowles, Rosemary A Parslow, Craig Harris

Biochem Soc Trans· June 2011

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Surface modification of chromatography adsorbents by low temperature low pressure plasma.
A Arpanaei, B Winther-Jensen, E Theodosiou, P Kingshott, T J Hobley

J Chromatogr A· October 2010

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Studies related to antibody fragment (Fab) production in Escherichia coli W3110 fed-batch fermentation processes using multiparameter flow cytometry.
Andrew Want, Owen R T Thomas, Bo Kara, John Liddell, Christopher J Hewitt

Cytometry A· February 2009

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Critical evaluation and comparison of fluid distribution systems for industrial scale expanded bed adsorption chromatography columns.
A Arpanaei, A Heebøll-Nielsen, J J Hubbuch, O R T Thomas, T J Hobley

J Chromatogr A· July 2008

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Lumped parameter model for prediction of initial breakthrough profiles for the chromatographic capture of antibodies from a complex feedstock.
Hanne Bak, Owen R T Thomas, Jens Abildskov

J Chromatogr B Analyt Technol Biomed Life Sci· March 2007

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High-throughput immunoturbidimetric assays for in-process determination of polyclonal antibody concentration and functionality in crude samples.
H Bak, J Kyhse-Andersen, O R T Thomas

J Chromatogr B Analyt Technol Biomed Life Sci· March 2007

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Evaluation of commercial chromatographic adsorbents for the direct capture of polyclonal rabbit antibodies from clarified antiserum.
H Bak, O R T Thomas

J Chromatogr B Analyt Technol Biomed Life Sci· March 2007

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Protein purification using magnetic adsorbent particles.
Matthias Franzreb, Martin Siemann-Herzberg, Timothy J Hobley, Owen R T Thomas

Appl Microbiol Biotechnol· May 2006

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