Publications by authors named "Thomas Perlmann"

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Sox9 and nuclear factor I transcription factors regulate the timing of neurogenesis and ependymal maturation in dopamine progenitors.
Laura Lahti, Nikolaos Volakakis, Linda Gillberg, Behzad Yaghmaeian Salmani, Katarína Tiklová, Thomas Perlmann

Development· March 2025

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Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice.
Ioannis Mantas, Ivana Flais, Yuvarani Masarapu, Tudor Ionescu, Solène Frapard, Thomas Perlmann

Nat Commun· September 2024

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Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model.
Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Thomas Perlmann

Elife· April 2024

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PARKIN is not required to sustain OXPHOS function in adult mammalian tissues.
Roberta Filograna, Jule Gerlach, Hae-Na Choi, Giovanni Rigoni, Michela Barbaro, Thomas Perlmann

NPJ Parkinsons Dis· April 2024

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Aberrant somatic calcium channel function in cNurr1 and LRRK2-G2019S mice.
Olga Skiteva, Ning Yao, Ioannis Mantas, Xiaoqun Zhang, Thomas Perlmann

NPJ Parkinsons Dis· April 2023

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Schwann cell precursors represent a neural crest-like state with biased multipotency.
Maria Eleni Kastriti, Louis Faure, Dorothea Von Ahsen, Thibault Gerald Bouderlique, Johan Boström, Thomas Perlmann

EMBO J· September 2022

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PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons.
Konstantinos Toskas, Behzad Yaghmaeian-Salmani, Olga Skiteva, Wojciech Paslawski, Linda Gillberg, Thomas Perlmann

Sci Adv· August 2022

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Lmx1a-Dependent Activation of miR-204/211 Controls the Timing of Nurr1-Mediated Dopaminergic Differentiation.
Salvatore Pulcrano, Roberto De Gregorio, Claudia De Sanctis, Laura Lahti, Carla Perrone-Capano, Thomas Perlmann

Int J Mol Sci· June 2022

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Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypes.
Behzad Yaghmaeian Salmani, Brad Balderson, Susanne Bauer, Helen Ekman, Annika Starkenberg, Thomas Perlmann

Development· March 2022

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Disease Duration Influences Gene Expression in Neuromelanin-Positive Cells From Parkinson's Disease Patients.
Katarína Tiklová, Linda Gillberg, Nikolaos Volakakis, Hilda Lundén-Miguel, Lina Dahl, Thomas Perlmann

Front Mol Neurosci· November 2021

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Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response.
Roberta Filograna, Seungmin Lee, Katarína Tiklová, Mara Mennuni, Viktor Jonsson, Thomas Perlmann

PLoS Genet· September 2021

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Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease.
Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, Åsa K Björklund, Yogita Sharma, Thomas Perlmann

Nat Commun· July 2020

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CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment.
Daniel W Hagey, Danijal Topcic, Nigel Kee, Florie Reynaud, Maria Bergsland, Thomas Perlmann

Nat Commun· June 2020

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Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease.
Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, Åsa K Björklund, Yogita Sharma, Thomas Perlmann

Nat Commun· May 2020

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Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development.
Katarína Tiklová, Åsa K Björklund, Laura Lahti, Alessandro Fiorenzano, Sara Nolbrant, Thomas Perlmann

Nat Commun· February 2019

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Author Correction: A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons.
Erik Södersten, Konstantinos Toskas, Vilma Rraklli, Katarina Tiklova, Åsa K Björklund, Thomas Perlmann

Nat Commun· November 2018

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A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons.
Erik Södersten, Konstantinos Toskas, Vilma Rraklli, Katarina Tiklova, Åsa K Björklund, Thomas Perlmann

Nat Commun· March 2018

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Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson's disease.
Holly Green, Xiaoqun Zhang, Katarina Tiklova, Nikolaos Volakakis, Lovisa Brodin, Thomas Perlmann

Proc Natl Acad Sci U S A· March 2017

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Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.
Agnete Kirkeby, Sara Nolbrant, Katarina Tiklova, Andreas Heuer, Nigel Kee, Thomas Perlmann

Cell Stem Cell· January 2017

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Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.
Nigel Kee, Nikolaos Volakakis, Agnete Kirkeby, Lina Dahl, Helena Storvall, Thomas Perlmann

Cell Stem Cell· January 2017

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The stem cell niche finds its true north.
Agnete Kirkeby, Thomas Perlmann, Carlos-Filipe Pereira

Development· August 2016

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The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2.
Stefanie Gross, Diana C Garofalo, Dina A Balderes, Teresa L Mastracci, José M Dias, Thomas Perlmann

Development· July 2016

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Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.
Hélène Doucet-Beaupré, Catherine Gilbert, Marcos Schaan Profes, Audrey Chabrat, Consiglia Pacelli, Thomas Perlmann

Proc Natl Acad Sci U S A· July 2016

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Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors.
Eva Hedlund, Laure Belnoue, Spyridon Theofilopoulos, Carmen Salto, Chris Bye, Thomas Perlmann

Sci Rep· June 2016

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Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.
Nikolaos Volakakis, Katarina Tiklova, Mickael Decressac, Maria Papathanou, Bengt Mattsson, Thomas Perlmann

J Neurosci· October 2015

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