Publications by authors named "Thomas Scanlan"

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Central thyroid hormone receptor-beta: Sensitivity to alcohol and a role in regulating alcohol drinking.
Michael C Johnson, Michelle A Nipper, Kelly M Abshire, Jessica E Rehmann, Jonathan A Zweig, Thomas S Scanlan

Horm Behav· November 2025

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Thyroid hormone receptor-β analogues for the treatment of metabolic dysfunction-associated steatohepatitis (MASH).
Vlad Ratziu, Thomas S Scanlan, Eveline Bruinstroop

J Hepatol· February 2025

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Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration.
Daniel R Hochbaum, Lauren Hulshof, Amanda Urke, Wengang Wang, Alexandra C Dubinsky, Thomas S Scanlan

Cell· October 2024

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Remyelination protects neurons from DLK-mediated neurodegeneration.
Greg J Duncan, Sam D Ingram, Katie Emberley, Jo Hill, Christian Cordano, Thomas S Scanlan

Nat Commun· October 2024

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Remyelination protects neurons from DLK-mediated neurodegeneration.
Greg J Duncan, Sam D Ingram, Katie Emberley, Jo Hill, Christian Cordano, Thomas Scanlan

bioRxiv· August 2024

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Promyelinating drugs promote functional recovery in an autism spectrum disorder mouse model of Pitt-Hopkins syndrome.
Joseph F Bohlen, Colin M Cleary, Debamitra Das, Srinidhi Rao Sripathy, Norah Sadowski, Thomas S Scanlan

Brain· August 2023

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Thyroid hormone rewires cortical circuits to coordinate body-wide metabolism and exploratory drive.
Daniel R Hochbaum, Alexandra C Dubinsky, Hannah C Farnsworth, Lauren Hulshof, Giona Kleinberg, Thomas Scanlan

bioRxiv· August 2023

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Maternal Administration of the CNS-Selective Sobetirome Prodrug Sob-AM2 Exerts Thyromimetic Effects in Murine MCT8-Deficient Fetuses.
Víctor Valcárcel-Hernández, Marina Guillén-Yunta, Thomas S Scanlan, Soledad Bárez-López, Ana Guadaño-Ferraz

Thyroid· May 2023

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TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptor.
Skylar J Ferrara, Priya Chaudhary, Margaret J DeBell, Gail Marracci, Hannah Miller, Thomas S Scanlan

Cell Chem Biol· February 2022

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is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptor.
Skylar J Ferrara, Priya Chaudhary, Margaret J DeBell, Gail Marracci, Hannah Miller, Thomas S Scanlan

bioRxiv· January 2021

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A CNS-Targeting Prodrug Strategy for Nuclear Receptor Modulators.
Skylar J Ferrara, Thomas S Scanlan

J Med Chem· September 2020

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Pharmacological Complementation Remedies an Inborn Error of Lipid Metabolism.
Meredith D Hartley, Mitra D Shokat, Margaret J DeBell, Tania Banerji, Lisa L Kirkemo, Thomas S Scanlan

Cell Chem Biol· May 2020

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N- and O-Acetylated 3-Iodothyronamines Have No Metabolic or Thermogenic Effects in Male Mice.
Sogol Gachkar, Rebecca Oelkrug, Beate Herrmann, Thomas S Scanlan, Qian Sun

Eur Thyroid J· February 2020

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Radiation-primed hepatocyte transplantation in murine monogeneic dyslipidemia normalizes cholesterol and prevents atherosclerosis.
Mark Barahman, Wei Zhang, Hillary Yaffe Harris, Anita Aiyer, Rafi Kabarriti, Thomas S Scanlan

J Hepatol· June 2019

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Response to Letter to the Editor: "Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy".
Terry J Smith, Thomas S Scanlan, Roshini Fernando

J Clin Endocrinol Metab· April 2019

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Thyroid hormone receptor function in maturing ovine cardiomyocytes.
Natasha N Chattergoon, Samantha Louey, Thomas Scanlan, Isa Lindgren, George D Giraud

J Physiol· April 2019

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Evidence for hormonal control of heart regenerative capacity during endothermy acquisition.
Kentaro Hirose, Alexander Y Payumo, Stephen Cutie, Alison Hoang, Hao Zhang, Thomas S Scanlan

Science· April 2019

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Myelin repair stimulated by CNS-selective thyroid hormone action.
Meredith D Hartley, Tania Banerji, Ian J Tagge, Lisa L Kirkemo, Priya Chaudhary, Thomas S Scanlan

JCI Insight· April 2019

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Quantification of Thyromimetic Sobetirome Concentration in Biological Tissue Samples.
Jordan Devereaux, Skylar J Ferrara, Thomas S Scanlan

Methods Mol Biol· February 2019

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Structure-Activity Relationships of Central Nervous System Penetration by Fatty Acid Amide Hydrolase (FAAH)-Targeted Thyromimetic Prodrugs.
J Matthew Meinig, Skylar J Ferrara, Tapasree Banerji, Tania Banerji, Hannah S Sanford-Crane, Thomas S Scanlan

ACS Med Chem Lett· January 2019

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Sobetirome and its Amide Prodrug Sob-AM2 Exert Thyromimetic Actions in Mct8-Deficient Brain.
Soledad Bárez-López, Meredith D Hartley, Carmen Grijota-Martínez, Thomas S Scanlan, Ana Guadaño-Ferraz

Thyroid· September 2018

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T Induces Both Markers of Maturation and Aging in Pancreatic β-Cells.
Cristina Aguayo-Mazzucato, Terence B Lee, Michelle Matzko, Amanda DiIenno, Habib Rezanejad, Thomas Scanlan

Diabetes· July 2018

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Hypothalamic-Pituitary-Thyroid Axis Perturbations in Male Mice by CNS-Penetrating Thyromimetics.
Skylar J Ferrara, Dennis Bourdette, Thomas S Scanlan

Endocrinology· July 2018

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Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.
Guoying Yu, Argyris Tzouvelekis, Rong Wang, Jose D Herazo-Maya, Gabriel H Ibarra, Thomas S Scanlan

Nat Med· January 2018

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Targeting Fatty-Acid Amide Hydrolase with Prodrugs for CNS-Selective Therapy.
J Matthew Meinig, Skylar J Ferrara, Tania Banerji, Tapasree Banerji, Hannah S Sanford-Crane, Thomas S Scanlan

ACS Chem Neurosci· November 2017

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