Publications by authors named "Thomas Zollner"

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A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding.
Chen-Yi Wang, Martin Philpott, Darragh P O'Brien, Anne Ndungu, Jessica Malzahn, Thomas M Zollner

Commun Med (Lond)· July 2025

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Discovery of IRAK4 Inhibitors (Zabedosertib) and .
Ulrich Bothe, Judith Günther, Reinhard Nubbemeyer, Holger Siebeneicher, Sven Ring, Thomas M Zollner

J Med Chem· January 2024

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Transition to Chronic Fibrosis in an Animal Model of Retinal Detachment With Features of Proliferative Vitreoretinopathy.
Cornelia Peterson, Yuchen Lu, Clayton P Santiago, Antoinette C Price, Minda M McNally, Thomas Zollner

Invest Ophthalmol Vis Sci· December 2023

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Anxiety-related behaviors without observation of generalized pain in a mouse model of endometriosis.
Paulina Nunez-Badinez, Alexis Laux-Biehlmann, Michael D Hayward, Olesia Buiakova, Thomas M Zollner

Front Behav Neurosci· February 2023

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Discovery of , a Selective CNS Penetrant Chemical Probe as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist.
Stefanie Mesch, Daryl Walter, Alexis Laux-Biehlmann, Daniel Basting, Stuart Flanagan, Thomas M Zollner

J Med Chem· January 2023

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Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers.
Adam J Davenport, Ioana Neagoe, Nico Bräuer, Markus Koch, Andrea Rotgeri, Thomas M Zollner

Sci Rep· October 2021

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Preclinical models of endometriosis and interstitial cystitis/bladder pain syndrome: an Innovative Medicines Initiative-PainCare initiative to improve their value for translational research in pelvic pain.
Paulina Nunez-Badinez, Bianca De Leo, Alexis Laux-Biehlmann, Anja Hoffmann, Thomas M Zollner

Pain· September 2021

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Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis.
Thomas T Tapmeier, Nilufer Rahmioglu, Jianghai Lin, Bianca De Leo, Maik Obendorf, Thomas M Zollner

Sci Transl Med· August 2021

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Discovery and Characterization of BAY 1214784, an Orally Available Spiroindoline Derivative Acting as a Potent and Selective Antagonist of the Human Gonadotropin-Releasing Hormone Receptor as Proven in a First-In-Human Study in Postmenopausal Women.
Olaf Panknin, Andrea Wagenfeld, Wilhelm Bone, Eckhard Bender, Katrin Nowak-Reppel, Thomas M Zollner

J Med Chem· October 2020

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Discovery of the potent non-steroidal glucocorticoid receptor modulator BAY 1003803 as clinical candidate.
Markus Berger, Ekkehard May, Hartmut Rehwinkel, Heike Schäcke, Roland Neuhaus, Thomas M Zollner

Bioorg Med Chem Lett· August 2020

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Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions.
Marie-Laëtitia Thézénas, Bianca De Leo, Alexis Laux-Biehlmann, Cemsel Bafligil, Bernd Elger, Thomas M Zollner

Sci Rep· March 2020

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Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study.
Manman Guo, Cemsel Bafligil, Thomas Tapmeier, Carol Hubbard, Sanjiv Manek, Thomas M Zollner

BMC Med· January 2020

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Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions.
Marie-Laëtitia Thézénas, Bianca De Leo, Alexis Laux-Biehlmann, Cemsel Bafligil, Bernd Elger, Thomas M Zollner

Sci Rep· January 2020

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Discovery and Characterization of the Potent and Selective P2X4 Inhibitor -[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile.
Stefan Werner, Stefanie Mesch, Roman C Hillig, Antonius Ter Laak, Julie Klint, Thomas M Zollner

J Med Chem· December 2019

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Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis.
Marcus Koppitz, Nico Bräuer, Antonius Ter Laak, Horst Irlbacher, Andrea Rotgeri, Thomas M Zollner

Bioorg Med Chem Lett· September 2019

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Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis.
Stefan Bäurle, Jens Nagel, Olaf Peters, Nico Bräuer, Antonius Ter Laak, Thomas M Zollner

J Med Chem· March 2019

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Optimized effective charge density and size of polyglycerol amines leads to strong knockdown efficacy in vivo.
Anna Maria Staedtler, Markus Hellmund, Fatemeh Sheikhi Mehrabadi, Bala N S Thota, Thomas M Zollner

J Mater Chem B· December 2015

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Menstruation pulls the trigger for inflammation and pain in endometriosis.
Alexis Laux-Biehlmann, Thomas d'Hooghe, Thomas M Zollner

Trends Pharmacol Sci· May 2015

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The CD24hi smooth muscle subpopulation is the predominant fraction in uterine fibroids.
Michael Drosch, Nicole Schmidt, Dominique Nadine Markowski, Thomas Matthias Zollner, Markus Koch

Mol Hum Reprod· July 2014

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Use of dynamic weight bearing as a novel end-point for the assessment of abdominal pain in the LPS-induced peritonitis model in the rat.
Michael Gruen, Alexis Laux-Biehlmann, Thomas M Zollner, Jens Nagel

J Neurosci Methods· July 2014

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Polyglycerol-based amphiphilic dendrons as potential siRNA carriers for in vivo applications.
Ariane Tschiche, Anna M Staedtler, Shashwat Malhotra, Hannah Bauer, Christoph Böttcher, Thomas M Zollner

J Mater Chem B· April 2014

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A novel mouse model that closely mimics human uterine leiomyomas.
Michael Drosch, Jörn Bullerdiek, Thomas M Zollner, Florian Prinz, Markus Koch

Fertil Steril· March 2013

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Cancer therapy monitoring in xenografts by quantitative analysis of circulating tumor DNA.
Tobias M Gorges, Johanna Schiller, Arndt Schmitz, Daniel Schuetzmann, Christoph Schatz, Thomas M Zollner

Biomarkers· September 2012

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Induction of overt menstruation in intact mice.
Marion Rudolph, Wolf-Dietrich Döcke, Andrea Müller, Astrid Menning, Lars Röse, Thomas Matthias Zollner

PLoS One· August 2012

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Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition.
Tobias M Gorges, Ingeborg Tinhofer, Michael Drosch, Lars Röse, Thomas M Zollner

BMC Cancer· May 2012

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