Publications by authors named "Tige Rustad"

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Divergent transcriptional regulation of redox-homeostasis and permeability modulate rifampicin tolerance and sensitivity in Mycobacterium tuberculosis.
Jees Sebastian, Shuyi Ma, Tige Rustad, Ethan Bustad, Anooja Thomas

Nat Commun· December 2025

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Predicting fitness in with transcriptional regulatory network-informed interpretable machine learning.
Ethan Bustad, Edson Petry, Oliver Gu, Braden T Griebel, Tige R Rustad

Front Tuberc· April 2025

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Predicting bacterial fitness in Mycobacterium tuberculosis with transcriptional regulatory network-informed interpretable machine learning.
Ethan Bustad, Edson Petry, Oliver Gu, Braden T Griebel, Tige R Rustad

bioRxiv· September 2024

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Re-evaluation of a novel resistance mutation in eccC5 of the ESX-5 secretion system in ofloxacin-resistant Mycobacterium tuberculosis.
Amondrea Blackman, Bob Morrison, Fernanda Maruri, Yuri van der Heijden, Cindy Hager Nochowicz, Tige Rustad

J Antimicrob Chemother· February 2021

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Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis.
Courtney R Plumlee, Fergal J Duffy, Benjamin H Gern, Jared L Delahaye, Sara B Cohen, Tige R Rustad

Cell Host Microbe· January 2021

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Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis.
Shuyi Ma, Robert Morrison, Samuel J Hobbs, Vijay Soni, Jessica Farrow-Johnson, Tige R Rustad

Nat Microbiol· January 2021

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Rapidly Correcting Frameshift Mutations in the Mycobacterium tuberculosis Gene Produce Reversible Ethambutol Resistance and Small-Colony-Variant Morphology.
Hassan Safi, Subramanya Lingaraju, Shuyi Ma, Seema Husain, Mainul Hoque, Tige Rustad

Antimicrob Agents Chemother· August 2020

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ODELAM, rapid sequence-independent detection of drug resistance in isolates of .
Thurston Herricks, Magdalena Donczew, Fred D Mast, Tige Rustad, Robert Morrison

Elife· May 2020

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Phase variation in produces transiently heritable drug tolerance.
Hassan Safi, Pooja Gopal, Subramanya Lingaraju, Shuyi Ma, Carly Levine, Tige Rustad

Proc Natl Acad Sci U S A· September 2019

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Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose.
Maikel Boot, Vincent J C van Winden, Marion Sparrius, Robert van de Weerd, Alexander Speer, Tige Rustad

PLoS Genet· December 2017

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Towards understanding the biological function of the unusual chaperonin Cpn60.1 (GroEL1) of Mycobacterium tuberculosis.
Aditi Sharma, Tige Rustad, Gaurang Mahajan, Arun Kumar, Kanury V S Rao

Tuberculosis (Edinb)· March 2016

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A comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis.
Serdar Turkarslan, Eliza J R Peterson, Tige R Rustad, Kyle J Minch, David J Reiss

Sci Data· December 2015

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Integrated Modeling of Gene Regulatory and Metabolic Networks in Mycobacterium tuberculosis.
Shuyi Ma, Kyle J Minch, Tige R Rustad, Samuel Hobbs, Suk-Lin Zhou

PLoS Comput Biol· November 2015

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Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network.
Tige R Rustad, Kyle J Minch, Shuyi Ma, Jessica K Winkler, Samuel Hobbs

Genome Biol· July 2015

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The DNA-binding network of Mycobacterium tuberculosis.
Kyle J Minch, Tige R Rustad, Eliza J R Peterson, Jessica Winkler, David J Reiss

Nat Commun· January 2015

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A high-resolution network model for global gene regulation in Mycobacterium tuberculosis.
Eliza J R Peterson, David J Reiss, Serdar Turkarslan, Kyle J Minch, Tige Rustad

Nucleic Acids Res· October 2014

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Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis.
Molly R Nixon, Kurt W Saionz, Mi-Sun Koo, Michael J Szymonifka, Hunmin Jung, Tige Rustad

Chem Biol· July 2014

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Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch.
Corrie Ortega, Reiling Liao, Lindsey N Anderson, Tige Rustad, Anja R Ollodart

PLoS Biol· January 2014

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Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase.
Stavroula K Hatzios, Christina E Baer, Tige R Rustad, M Sloan Siegrist, Jennifer M Pang

Proc Natl Acad Sci U S A· December 2013

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The Mycobacterium tuberculosis regulatory network and hypoxia.
James E Galagan, Kyle Minch, Matthew Peterson, Anna Lyubetskaya, Elham Azizi, Tige Rustad

Nature· July 2013

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Global analysis of mRNA stability in Mycobacterium tuberculosis.
Tige R Rustad, Kyle J Minch, William Brabant, Jessica K Winkler, David J Reiss

Nucleic Acids Res· January 2013

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Bioinformatic and empirical analysis of novel hypoxia-inducible targets of the human antituberculosis T cell response.
Hannah P Gideon, Katalin A Wilkinson, Tige R Rustad, Tolu Oni, Heinner Guio

J Immunol· December 2012

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Mycobacterium tuberculosis growth following aerobic expression of the DosR regulon.
Kyle Minch, Tige Rustad, David R Sherman

PLoS One· September 2012

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Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines.
Hannah Priyadarshini Gideon, Katalin Andrea Wilkinson, Tige R Rustad, Tolu Oni, Heinner Guio

PLoS Pathog· December 2010

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Characterization of a Clp protease gene regulator and the reaeration response in Mycobacterium tuberculosis.
Ashley M Sherrid, Tige R Rustad, Gerard A Cangelosi, David R Sherman

PLoS One· July 2010

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