Publications by authors named "Tim Fennell"

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Fast and accurate kinship estimation using sparse SNPs in relatively large database searches.
June Snedecor, Tim Fennell, Seth Stadick, Nils Homer, Joana Antunes

Forensic Sci Int Genet· November 2022

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CALITAS: A CRISPR-Cas-aware ALigner for off-TArget Search.
Tim Fennell, Deric Zhang, Meltem Isik, Tongyao Wang, Gregory Gotta

CRISPR J· April 2021

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Detecting sample swaps in diverse NGS data types using linkage disequilibrium.
Nauman Javed, Yossi Farjoun, Tim J Fennell, Charles B Epstein, Bradley E Bernstein

Nat Commun· July 2020

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Synthesis of [ H] and [ C]genipin.
Adele E Queen, David Hesk, David M Lindsay, William J Kerr, Kenneth Rehder, Tim Fennell

J Labelled Comp Radiopharm· April 2020

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Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10.
Morgan L Maeder, Michael Stefanidakis, Christopher J Wilson, Reshica Baral, Luis Alberto Barrera, Tim J Fennell

Nat Med· February 2019

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Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".
Christopher J Wilson, Tim Fennell, Anne Bothmer, Morgan L Maeder, Deepak Reyon

Nat Methods· April 2018

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Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

N Engl J Med· June 2015

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A polygenic burden of rare disruptive mutations in schizophrenia.
Shaun M Purcell, Jennifer L Moran, Menachem Fromer, Douglas Ruderfer, Nadia Solovieff, Tim Fennell

Nature· February 2014

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Peripherally selective diphenyl purine antagonist of the CB1 receptor.
Alan Fulp, Katherine Bortoff, Yanan Zhang, Rodney Snyder, Tim Fennell

J Med Chem· October 2013

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Patterns and rates of exonic de novo mutations in autism spectrum disorders.
Benjamin M Neale, Yan Kou, Li Liu, Avi Ma'ayan, Kaitlin E Samocha, Tim Fennell

Nature· April 2012

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Design and synthesis of cannabinoid receptor 1 antagonists for peripheral selectivity.
Alan Fulp, Katherine Bortoff, Herbert Seltzman, Yanan Zhang, James Mathews, Tim Fennell

J Med Chem· March 2012

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Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.
Manuel A Rivas, Mélissa Beaudoin, Agnes Gardet, Christine Stevens, Yashoda Sharma, Tim Fennell

Nat Genet· October 2011

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ContEst: estimating cross-contamination of human samples in next-generation sequencing data.
Kristian Cibulskis, Aaron McKenna, Tim Fennell, Eric Banks, Mark DePristo

Bioinformatics· September 2011

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A framework for variation discovery and genotyping using next-generation DNA sequencing data.
Mark A DePristo, Eric Banks, Ryan Poplin, Kiran V Garimella, Jared R Maguire, Tim J Fennell

Nat Genet· May 2011

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Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia.
Kiran Musunuru, James P Pirruccello, Ron Do, Gina M Peloso, Candace Guiducci, Tim Fennell

N Engl J Med· December 2010

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High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.
Yung-Hao Ching, Robert J Munroe, Jennifer L Moran, Anna K Barker, Evan Mauceli, Tim Fennell

BMC Genet· November 2010

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Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.
Jordi Barretina, Barry S Taylor, Shantanu Banerji, Alexis H Ramos, Mariana Lagos-Quintana, Tim J Fennell

Nat Genet· August 2010

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Targeted exon sequencing by in-solution hybrid selection.
Brendan Blumenstiel, Kristian Cibulskis, Sheila Fisher, Matthew DeFelice, Andrew Barry, Tim Fennell

Curr Protoc Hum Genet· July 2010

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The Sequence Alignment/Map format and SAMtools.
Heng Li, Bob Handsaker, Alec Wysoker, Tim Fennell, Jue Ruan

Bioinformatics· August 2009

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Somatic mutations affect key pathways in lung adenocarcinoma.
Li Ding, Gad Getz, David A Wheeler, Elaine R Mardis, Michael D McLellan, Tim Fennell

Nature· October 2008

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Drug-sensitive FGFR2 mutations in endometrial carcinoma.
Amit Dutt, Helga B Salvesen, Tzu-Hsiu Chen, Alex H Ramos, Robert C Onofrio, Tim Fennell

Proc Natl Acad Sci U S A· June 2008

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