Publications by authors named "Tim H Huang"

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An Integrated Approach to Knowledge and Prediction Modeling of Breast Cancer Metastasis Using Gene Regulatory Networks.
Tanzira Najnin, Sakhawat Hossain Saimon, Maryam Zand, Nahim Adnan, Zhijie Liu, Tim Hui-Ming Huang

IEEE Trans Comput Biol Bioinform· December 2025

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Identification of a 5-gene signature panel for the prediction of prostate cancer progression.
Michelle Shen, Fernando García-Marqués, Arvind Muruganantham, Shiqin Liu, James Robert White, Tim H Huang

Br J Cancer· December 2024

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PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms.
Li-Ling Lin, Bijaya Nayak, Pawel A Osmulski, Exing Wang, Chen-Pin Wang, Tim H-M Huang

Cell Rep· August 2024

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Targeting hepatic serine-arginine protein kinase 2 ameliorates alcohol-associated liver disease by alternative splicing control of lipogenesis.
Guannan Li, Hanqing Chen, Feng Shen, Steven Blake Smithson, Gavyn Lee Shealy, Tim H Huang

Hepatology· November 2023

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Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions.
Lizhen Chen, Zhao Zhang, Qinyu Han, Barun K Maity, Leticia Rodrigues, Tim Hui-Ming Huang

Mol Cell· October 2023

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Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination.
Chih-Wei Chou, Chia-Nung Hung, Cheryl Hsiang-Ling Chiu, Xi Tan, Meizhen Chen, Tim Hui-Ming Huang

Nat Commun· October 2023

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AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages.
Chia-Nung Hung, Meizhen Chen, Daniel T DeArmond, Cheryl H-L Chiu, Catherine A Limboy, Tim H-M Huang

Cell Rep· September 2023

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KLRF1, a novel marker of CD56 NK cells, predicts improved survival for patients with locally advanced bladder cancer.
Neelam Mukherjee, Niannian Ji, Xi Tan, Chun-Liang Chen, Onika D V Noel, Tim H Huang

Cancer Med· April 2023

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PRC2-Mediated Epigenetic Suppression of Type I IFN-STAT2 Signaling Impairs Antitumor Immunity in Luminal Breast Cancer.
Juyeong Hong, Ji Hoon Lee, Zhao Zhang, Yanming Wu, Mei Yang, Tim H-M Huang

Cancer Res· December 2022

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A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer.
Kristin A Altwegg, Suryavathi Viswanadhapalli, Monica Mann, Dimple Chakravarty, Samaya Krishnan, Tim H-M Huang

Cancer Res· October 2022

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Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.
Sakie Katsumura, Nadeem Siddiqui, Michael Rock Goldsmith, Jaime H Cheah, Teppei Fujikawa, Tim H-M Huang

Cell Metab· April 2022

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Single-cell RNA profiling identifies diverse cellular responses to EWSR1/FLI1 downregulation in Ewing sarcoma cells.
Roxane Khoogar, Fuyang Li, Yidong Chen, Myron Ignatius, Elizabeth R Lawlor, Tim H-M Huang

Cell Oncol (Dordr)· February 2022

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GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer.
Marieke Burleson, Janice J Deng, Tai Qin, Thu Minh Duong, Yuqian Yan, Tim Hui-Ming Huang, Haojie Huang

Mol Cancer Res· January 2022

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Cellular junction and mesenchymal factors delineate an endometriosis-specific response of endometrial stromal cells to the mesothelium.
Li-Ling Lin, Simran Makwana, Meizhen Chen, Chiou-Miin Wang, Laurel H Gillette, Tim H Huang

Mol Cell Endocrinol· January 2022

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2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity.
Meena Kusi, Maryam Zand, Li-Ling Lin, Meizhen Chen, Anthony Lopez, Tim H-M Huang

Cell Rep· January 2022

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FOXP3 Is an X-Linked Breast Cancer Suppressor Gene and an Important Repressor of the HER-2/ErbB2 Oncogene.
Tao Zuo, Lizhong Wang, Carl Morrison, Xing Chang, Huiming Zhang, Tim H-M Huang

Cell· December 2021

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Contacts with Macrophages Promote an Aggressive Nanomechanical Phenotype of Circulating Tumor Cells in Prostate Cancer.
Pawel A Osmulski, Alessandra Cunsolo, Meizhen Chen, Yusheng Qian, Chun-Lin Lin, Tim H-M Huang

Cancer Res· August 2021

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Detection of DNA Methylation by MeDIP and MBDCap Assays: An Overview of Techniques.
Hang-Kai Hsu, Yu-I Weng, Pei-Yin Hsu, Tim H-M Huang, Yi-Wen Huang

Methods Mol Biol· October 2020

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PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer.
Li-Ling Lin, Edward R Kost, Chun-Lin Lin, Philip Valente, Chiou-Miin Wang, Tim H-M Huang

Cell Rep· October 2020

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Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.
Chih-Wei Chou, Xi Tan, Chia-Nung Hung, Brandon Lieberman, Meizhen Chen, Tim Hui-Ming Huang

Cancers (Basel)· September 2020

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Modeling and analysis of Hi-C data by HiSIF identifies characteristic promoter-distal loops.
Yufan Zhou, Xiaolong Cheng, Yini Yang, Tian Li, Jingwei Li, Tim H-M Huang

Genome Med· August 2020

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Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance.
Mingjun Bi, Zhao Zhang, Yi-Zhou Jiang, Pengya Xue, Hu Wang, Tim Hui-Ming Huang

Nat Cell Biol· June 2020

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Age-associated genes in human mammary gland drive human breast cancer progression.
Xiang Gu, Bingzhi Wang, Haiyan Zhu, You Zhou, Aaron M Horning, Tim H-M Huang

Breast Cancer Res· June 2020

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ERα-related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer.
Chun-Lin Lin, Xi Tan, Meizhen Chen, Meena Kusi, Chia-Nung Hung, Tim H-M Huang

BMC Med Genomics· May 2020

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Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer.
Josephine A Taverna, Chia-Nung Hung, Daniel T DeArmond, Meizhen Chen, Chun-Lin Lin, Tim H-M Huang

Cancer Res· April 2020

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