Publications by authors named "Tim Hammonds"

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USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma.
E Josue Ruiz, Adan Pinto-Fernandez, Andrew P Turnbull, Linxiang Lan, Thomas M Charlton, Tim R Hammonds

Elife· October 2021

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Evaluating and comparing immunostaining and computational methods for spatial profiling of drug response in patient-derived explants.
Gareth J Miles, Ian Powley, Seid Mohammed, Lynne Howells, J Howard Pringle, Tim Hammonds

Lab Invest· March 2021

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The deubiquitylase USP9X controls ribosomal stalling.
Anne Clancy, Claire Heride, Adán Pinto-Fernández, Hannah Elcocks, Andreas Kallinos, Tim Hammonds

J Cell Biol· March 2021

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Correction: The deubiquitylase USP9X controls ribosomal stalling.
Anne Clancy, Claire Heride, Adán Pinto-Fernández, Hannah Elcocks, Andreas Kallinos, Tim Hammonds

J Cell Biol· March 2021

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Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity.
Adan Pinto-Fernandez, Mariolina Salio, Tom Partridge, Jianzhou Chen, George Vere, Tim R Hammonds

Br J Cancer· February 2021

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Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery.
Ian R Powley, Meeta Patel, Gareth Miles, Howard Pringle, Lynne Howells, Tim Hammonds

Br J Cancer· March 2020

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Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4.
Stephanie M Myers, Duncan C Miller, Lauren Molyneux, Mercedes Arasta, Ruth H Bawn, Tim Hammonds

Eur J Med Chem· September 2019

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Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
Andrew P Turnbull, Stephanos Ioannidis, Wojciech W Krajewski, Adan Pinto-Fernandez, Claire Heride, Tim R Hammonds

Nature· October 2017

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High-Throughput Screening and Hit Validation of Extracellular-Related Kinase 5 (ERK5) Inhibitors.
Stephanie M Myers, Ruth H Bawn, Louise C Bisset, Timothy J Blackburn, Betty Cottyn, Tim Hammonds

ACS Comb Sci· August 2016

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Academic-Pharma drug discovery alliances: seeking ways to eliminate the valley of death.
Tim Hammonds

Future Med Chem· July 2016

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LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation.
Katerina Mardilovich, Mark Baugh, Diane Crighton, Dominika Kowalczyk, Mads Gabrielsen, Tim Hammonds

Oncotarget· November 2015

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Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti-Invasive Properties.
Mark D Charles, Joanna L Brookfield, Tennyson C Ekwuru, Martin Stockley, John Dunn, Tim Hammonds

J Med Chem· October 2015

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Addressing the right targets in oncology: challenges and alternative approaches.
Julie K Stock, Neil P Jones, Tim Hammonds, Jon Roffey, Christian Dillon

J Biomol Screen· March 2015

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Development of a high-throughput screening method for LIM kinase 1 using a luciferase-based assay of ATP consumption.
Mokdad Mezna, Ai Ching Wong, Margaret Ainger, Rebecca W Scott, Tim Hammonds

J Biomol Screen· April 2012

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Dynamic telomerase gene suppression via network effects of GSK3 inhibition.
Alan E Bilsland, Stacey Hoare, Katrina Stevenson, Jane Plumb, Natividad Gomez-Roman, Tim Hammonds

PLoS One· July 2009

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