Publications by authors named "Tim S Maughan"

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AI-powered immune profiling from histopathology slides for chemo-radiotherapy outcome prediction in rectal cancer: a study using clinical trial and real-world cohorts.
Zhuoyan Shen, Douglas Brand, Mikaël Simard, Adam P Levine, Sumeet Hindocha, Tim S Maughan

EBioMedicine· December 2025

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Coevolution of Atypical BRAF and KRAS Mutations in Colorectal Tumorigenesis.
Connor E Woolley, Enric Domingo, Juan Fernandez-Tajes, Kathryn A F Pennel, Patricia Roxburgh, Tim S Maughan

Mol Cancer Res· April 2025

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A Phase Ia/b study of MEK1/2 inhibitor binimetinib with MET inhibitor crizotinib in patients with RAS mutant advanced colorectal cancer (MErCuRIC).
Francesca Aroldi, Elena Elez, Thierry André, Geraldine Perkins, Hans Prenen, Tim S Maughan

BMC Cancer· April 2025

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A phase Ia study of the MEK1/2 inhibitor PD-0325901 with the c-MET inhibitor crizotinib in patients with advanced solid cancers.
Peter Gallagher, Christian Rolfo, Elena Elez, Julien Taieb, Jennifer Houlden, Tim S Maughan

BJC Rep· March 2025

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Standard or high dose chemoradiotherapy, with or without the protease inhibitor nelfinavir, in patients with locally advanced pancreatic cancer: The phase 1/randomised phase 2 SCALOP-2 trial.
Somnath Mukherjee, Cathy Qi, Rachel Shaw, Christopher M Jones, John A Bridgewater, Tim S Maughan

Eur J Cancer· September 2024

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Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures.
Umair Mahmood, Andrew Blake, Sanjay Rathee, Leslie Samuel, Graeme Murray, Tim S Maughan

Cancer Res Commun· July 2024

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New role of fat-free mass in cancer risk linked with genetic predisposition.
Benjamin H L Harris, Matteo Di Giovannantonio, Ping Zhang, David A Harris, Simon R Lord, Tim S Maughan

Sci Rep· March 2024

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FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing.
Susan D Richman, Gemma Hemmings, Helen Roberts, Niall Gallop, Rachel Dodds, Tim S Maughan

J Clin Pathol· August 2023

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NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch.
Séan M O'Cathail, Chieh-Hsi Wu, Rachael Thomas, Maria A Hawkins, Tim S Maughan

Antioxidants (Basel)· August 2021

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The Challenge of Combining Chemo- and Radiotherapy with Checkpoint Kinase Inhibitors.
Linda van Bijsterveldt, Samuel C Durley, Tim S Maughan, Timothy C Humphrey

Clin Cancer Res· February 2021

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Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia.
Stephanie G Craig, Matthew P Humphries, Matthew Alderdice, Victoria Bingham, Susan D Richman, Tim S Maughan

Br J Cancer· October 2020

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Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci.
Tomas Tanskanen, Linda van den Berg, Niko Välimäki, Mervi Aavikko, Eivind Ness-Jensen, Tim S Maughan

Int J Cancer· February 2018

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Patterns of progression, treatment of progressive disease and post-progression survival in the New EPOC study.
Siân A Pugh, Megan Bowers, Alexandre Ball, Stephen Falk, Meg Finch-Jones, Tim S Maughan

Br J Cancer· August 2016

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Cetuximab Is Contraindicated in the Perioperative Treatment of Colorectal Liver Metastases.
John N Primrose, David Cunningham, O James Garden, Tim S Maughan, Siân A Pugh

J Clin Oncol· July 2015

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Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN, and FOCUS studies.
Sabine Venderbosch, Iris D Nagtegaal, Tim S Maughan, Christopher G Smith, Jeremy P Cheadle

Clin Cancer Res· October 2014

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Pathological grading of regression following neoadjuvant chemoradiation therapy: the clinical need is now.
Tom P MacGregor, Tim S Maughan, Ricky A Sharma

J Clin Pathol· October 2012

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The clinical impact of expert pathological review on lymphoma management: a regional experience.
Jason F Lester, Stefan D Dojcinov, Richard L Attanoos, Ciaran J O'Brien, Tim S Maughan

Br J Haematol· November 2003

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