Publications by authors named "Tim Sproul"

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Design and Characterization of an Anti-Clec9a Antibody Armed with CpG Oligonucleotides To Enable Targeted Delivery of Adjuvant to Cross-Presenting Dendritic Cells.
Sayumi Yamazoe, Keerthi Sadanala, Qian Zhang, Arvind Rajpal, Tim Sproul

ACS Chem Biol· September 2025

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Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells.
Emanuela Sega, Srikanth Kotapati, Yam B Poudel, Qinqin Cheng, Keerthi Sadanala, Tim Sproul

Bioconjug Chem· March 2025

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Improved therapeutic index of an acidic pH-selective antibody.
Peter S Lee, Katherine G MacDonald, Evan Massi, Pamela V Chew, Christine Bee, Tim Sproul

MAbs· April 2022

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Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model.
Julie A Zorn, Matthew L Wheeler, Ralston M Barnes, Jim Kaberna, Winse Morishige, Tim Sproul

Sci Rep· March 2022

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Fc-Optimized Anti-CCR8 Antibody Depletes Regulatory T Cells in Human Tumor Models.
Joseph R Campbell, Bryan R McDonald, Paul B Mesko, Nathan O Siemers, Priti B Singh, Tim W Sproul

Cancer Res· June 2021

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Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models.
Feng Wang, Jordan C Tsai, Jonathan H Davis, Bryant Chau, Jia Dong, Tim Sproul

MAbs· January 2021

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