Publications by authors named "Arvind Rajpal"

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Engineered ipilimumab variants that bind human and mouse CTLA-4.
Brett Robison, S J Diong, Anusha Kumar, Thomas M Moon, Olin Chang, Arvind Rajpal

MAbs· December 2025

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Design and Characterization of Prodrugged Anti-CTLA-4 Antibodies.
Sayumi Yamazoe, Mary Huber, Srikanth Kotapati, Rahima Akter, Aarti Jashnani, Arvind Rajpal

Chembiochem· November 2025

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Design and Characterization of an Anti-Clec9a Antibody Armed with CpG Oligonucleotides To Enable Targeted Delivery of Adjuvant to Cross-Presenting Dendritic Cells.
Sayumi Yamazoe, Keerthi Sadanala, Qian Zhang, Arvind Rajpal, Tim Sproul

ACS Chem Biol· September 2025

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The Impact of Conjugation Mode and Site on Tubulysin Antibody-Drug-Conjugate Efficacy and Stability.
Sayumi Yamazoe, Qinqin Cheng, Srikanth Kotapati, Vangipuram S Rangan, Mei-Chen Sung, Arvind Rajpal

ChemistryOpen· August 2025

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Epitope Mapping Using Yeast Display and Next Generation Sequencing.
Thomas Van Blarcom, Andrea Rossi, Davide Foletti, Purnima Sundar, Steven Pitts, Arvind Rajpal

Methods Mol Biol· July 2025

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Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT.
Sj J Diong, Aarti Jashnani, Andrew W Drake, Christine Bee, Felix Findeisen, Arvind Rajpal

MAbs· November 2023

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Residue-Level Characterization of Antibody Binding Epitopes Using Carbene Chemical Footprinting.
Jason M Hogan, Peter S Lee, Susan C Wong, Sean M West, Winse H Morishige, Arvind Rajpal

Anal Chem· February 2023

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Designing antibodies as therapeutics.
Paul J Carter, Arvind Rajpal

Cell· July 2022

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Tim-3 mediates T cell trogocytosis to limit antitumor immunity.
Ornella Pagliano, Robert M Morrison, Joe-Marc Chauvin, Hridesh Banerjee, Diwakar Davar, Arvind Rajpal

J Clin Invest· May 2022

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Antibody blockade of CD96 by distinct molecular mechanisms.
Peter S Lee, Bryant Chau, Ishita Barman, Christine Bee, Aarti Jashnani, Arvind Rajpal

MAbs· April 2022

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Improved therapeutic index of an acidic pH-selective antibody.
Peter S Lee, Katherine G MacDonald, Evan Massi, Pamela V Chew, Christine Bee, Arvind Rajpal

MAbs· April 2022

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Impact of Drug Conjugation on Thermal and Metabolic Stabilities of Aglycosylated and -Glycosylated Antibodies.
Sayumi Yamazoe, Srikanth Kotapati, Jason M Hogan, Sean M West, Xiaodi A Deng, Arvind Rajpal

Bioconjug Chem· April 2022

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Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model.
Julie A Zorn, Matthew L Wheeler, Ralston M Barnes, Jim Kaberna, Winse Morishige, Arvind Rajpal

Sci Rep· March 2022

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High-Throughput Surface Plasmon Resonance Biosensors for Identifying Diverse Therapeutic Monoclonal Antibodies.
Zimple Matharu, Christine Bee, Flavio Schwarz, Haibin Chen, Matthew Tomlinson, Arvind Rajpal

Anal Chem· December 2021

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Automated and Faster Affinity Capture Method for Biotransformation Assessment of Site-Specific Antibody Drug Conjugates.
Aarti Jashnani, Srikanth Kotapati, Madhura Deshpande, Sayumi Yamazoe, Pavel Strop, Arvind Rajpal

Anal Chem· April 2021

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Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions.
Feng Wang, Bryant Chau, Sean M West, Christopher R Kimberlin, Fei Cao, Arvind Rajpal

Nat Commun· March 2021

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Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models.
Feng Wang, Jordan C Tsai, Jonathan H Davis, Bryant Chau, Jia Dong, Arvind Rajpal

MAbs· January 2021

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Design, Synthesis, and Structure-Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody-Drug Conjugates.
Naidu S Chowdari, Yong Zhang, Ivar McDonald, Walter Johnson, David R Langley, Arvind Rajpal

J Med Chem· November 2020

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Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody.
Amir A Al-Khami, Sawsan Youssef, Yasmina Abdiche, HoangKim Nguyen, Joyce Chou, Arvind Rajpal

Mol Cancer Ther· October 2020

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Integrated Approach for Characterizing Bispecific Antibody/Antigens Complexes and Mapping Binding Epitopes with SEC/MALS, Native Mass Spectrometry, and Protein Footprinting.
Richard Y-C Huang, Feng Wang, Matthew Wheeler, Yun Wang, Robert Langish, Arvind Rajpal

Anal Chem· August 2020

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High-Throughput Platform to Identify Antibody Conjugation Sites from Antibody-Drug Conjugate Libraries.
Sayumi Yamazoe, Jason M Hogan, Sean M West, Xiaodi A Deng, Srikanth Kotapati, Arvind Rajpal

Bioconjug Chem· April 2020

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Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies.
Srikanth Kotapati, David Passmore, Sayumi Yamazoe, Rajesh Kishore Kumar Sanku, Qiang Cong, Arvind Rajpal

Anal Chem· January 2020

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Preclinical Efficacy and Safety Comparison of CD3 Bispecific and ADC Modalities Targeting BCMA for the Treatment of Multiple Myeloma.
Siler H Panowski, Tracy C Kuo, Yi Zhang, Amy Chen, Tao Geng, Arvind Rajpal

Mol Cancer Ther· November 2019

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VISTA is an acidic pH-selective ligand for PSGL-1.
Robert J Johnston, Linhui Julie Su, Jason Pinckney, David Critton, Eric Boyer, Arvind Rajpal

Nature· October 2019

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Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma.
Cesar Sommer, Bijan Boldajipour, Tracy C Kuo, Trevor Bentley, Janette Sutton, Arvind Rajpal

Mol Ther· June 2019

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