Publications by authors named "Timi Edeki"

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Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients.
John S Bradley, Jon Armstrong, Antonio Arrieta, Raafat Bishai, Shampa Das, Timi Edeki

Antimicrob Agents Chemother· October 2016

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A Randomized, Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of Ceftazidime-Avibactam in Healthy Chinese Subjects.
Jianguo Li, Maria Learoyd, Furong Qiu, LeiLei Zhu, Timi Edeki

Clin Drug Investig· February 2016

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An open-label, non-randomised, phase 1, single-dose study to assess the pharmacokinetics of ceftaroline in patients with end-stage renal disease requiring intermittent haemodialysis.
Maria Sunzel, Maria Learoyd, Jianguo Li, Yan Li, Ngoc Ngo, Timi Edeki

Int J Antimicrob Agents· December 2015

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Phase 1 study assessing the steady-state concentration of ceftazidime and avibactam in plasma and epithelial lining fluid following two dosing regimens.
David P Nicolau, Leonard Siew, Jon Armstrong, James Li, Timi Edeki

J Antimicrob Chemother· October 2015

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Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects.
Shampa Das, Jianguo Li, Jon Armstrong, Maria Learoyd, Timi Edeki

Pharmacol Res Perspect· October 2015

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Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers.
Nobumitsu Tominaga, Timi Edeki, James Li, Maria Learoyd, M René Bouw

J Infect Chemother· August 2015

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Evaluation of the pharmacokinetics and safety of single and multiple ceftaroline fosamil infusions in healthy Chinese and Western subjects.
Li Yang, Maria Sunzel, Peng Xu, Timi Edeki, David Wilson

Int J Clin Pharmacol Ther· August 2015

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Safety, local tolerability and pharmacokinetics of ceftaroline fosamil administered in a reduced infusion volume.
Timi Edeki, Mirjana Kujacic, Helen Broadhurst, Jianguo Li, Maria Sunzel

Br J Clin Pharmacol· December 2014

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Assessment of the mass balance recovery and metabolite profile of avibactam in humans and in vitro drug-drug interaction potential.
Karthick Vishwanathan, Stuart Mair, Anshul Gupta, James Atherton, Jacqueline Clarkson-Jones, Timi Edeki

Drug Metab Dispos· May 2014

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Randomized, placebo-controlled study to assess the impact on QT/QTc interval of supratherapeutic doses of ceftazidime-avibactam or ceftaroline fosamil-avibactam.
Shampa Das, Jon Armstrong, David Mathews, Jianguo Li, Timi Edeki

J Clin Pharmacol· March 2014

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A placebo-controlled, double-blind, dose-escalation study to assess the safety, tolerability and pharmacokinetics/pharmacodynamics of single and multiple intravenous infusions of AZD9773 in patients with severe sepsis and septic shock.
Peter E Morris, Brian Zeno, Andrew C Bernard, Xiangning Huang, Shampa Das, Timi Edeki

Crit Care· February 2012

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PhRMA survey on the conduct of first-in-human clinical trials under exploratory investigational new drug applications.
Adel H Karara, Timi Edeki, James McLeod, Alfred P Tonelli, John A Wagner

J Clin Pharmacol· April 2010

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PhRMA white paper on ADME pharmacogenomics.
J Andrew Williams, Tommy Andersson, Tommy B Andersson, Rebecca Blanchard, Martin Otto Behm, Timi Edeki

J Clin Pharmacol· July 2008

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Induction of cyp3a in primary cultures of human hepatocytes by ginkgolides a and B.
Nu He, Hong-Bo Cai, Hong-Guang Xie, Xavior Collins, Timi I Edeki

Clin Exp Pharmacol Physiol· July 2007

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Effects of individual ginsenosides, ginkgolides and flavonoids on CYP2C19 and CYP2D6 activity in human liver microsomes.
Nu He, Hong-Guang Xie, Xavier Collins, Timi Edeki, Zhengyin Yan

Clin Exp Pharmacol Physiol· September 2006

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Erythrocytosis in a scleroderma patient.
Eric Mabo, Timi Edeki, Gloria E Westney, James W Reed, Xiaoqing Guo

Mt Sinai J Med· May 2006

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Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics.
David A Katz, Robert Carr, David R Grimm, Hao Xiong, Rhonda Holley-Shanks, Timi Edeki

Clin Pharmacol Ther· March 2006

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Evaluation of the potential for pharmacokinetic interaction between fenofibrate and ezetimibe: A phase I, open-label, multiple-dose, three-period crossover study in healthy subjects.
Linda E Gustavson, Sarah M Schweitzer, David A Burt, Ramanuj Achari, Matthew J Rieser, Timi Edeki

Clin Ther· March 2006

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A phase I multiple-dose escalation study characterizing pharmacokinetics and safety of ABT-578 in healthy subjects.
Chetan S Karyekar, Rajendra S Pradhan, Tony Freeney, Qin Ji, Timi Edeki

J Clin Pharmacol· August 2005

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American Society for Clinical Pharmacology and Therapeutics position statement on dietary supplement safety and regulation.
Jason D Morrow, Timi I Edeki, Mohamed El Mouelhi, Raymond E Galinsky, Rose Kovelesky

Clin Pharmacol Ther· March 2005

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The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes.
Nu He, Timi Edeki

Am J Ther· August 2004

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Depression as a risk factor for Alzheimer disease: the MIRAGE Study.
Robert C Green, L Adrienne Cupples, Alex Kurz, Sanford Auerbach, Rodney Go, Timi Edeki

Arch Neurol· May 2003

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Association between apolipoprotein E genotype and Alzheimer disease in African American subjects.
Neill R Graff-Radford, Robert C Green, Rodney C P Go, Michael L Hutton, Timi Edeki

Arch Neurol· April 2002

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Inhibitory effects of H1-antihistamines on CYP2D6- and CYP2C9-mediated drug metabolic reactions in human liver microsomes.
Nu He, Wen-Qi Zhang, Dolores Shockley, Timi Edeki

Eur J Clin Pharmacol· February 2002

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Risk of dementia among white and African American relatives of patients with Alzheimer disease.
Robert C Green, L Adrienne Cupples, Rodney Go, Kelly S Benke, Timi Edeki

JAMA· January 2002

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