Publications by authors named "Timo D Muller"

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C-COMPASS: a user-friendly neural network tool profiles cell compartments at protein and lipid levels.
Daniel T Haas, Daniel Weindl, Pamela Kakimoto, Eva-Maria Trautmann, Julia P Schessner

Nat Methods· December 2025

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Advances in incretin-based drug discovery in 2025.
Timo D Müller

Nat Rev Endocrinol· December 2025

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One small molecule for man, one giant leap for mankind with obesity.
Aaron Novikoff, Timo D Müller

Med· December 2025

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GLP-1/GIP/GCG receptor triagonist (IUB447) enhances insulin secretion via GLP-1 receptor and Gαq signalling pathway in mice.
Pascale C F Schreier, Philipp Beyerle, Severin Boulassel, Andreas Beck, Aaron Novikoff

Diabetologia· November 2025

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A novel tamoxifen-inducible Mct8-CreERT2 mouse model for targeted studies of Mct8-expressing cells and thyroid hormone transport and function.
Anna Molenaar, Noémi Mallet, Marin Bralo, Luciano J Hoeher, Sonja C Schriever

Transgenic Res· November 2025

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A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice.
Jonathan D Douros, Aaron Novikoff, Barent DuBois, Rebecca Rohlfs, Jacek Mokrosinski

Mol Metab· October 2025

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A consensus guide to preclinical indirect calorimetry experiments.
Alexander S Banks, David B Allison, Thierry Alquier, Ansarullah, Steven N Austad

Nat Metab· September 2025

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Tirzepatide differentially affects body weight in mice and humans.
Aaron Novikoff, Timo D Müller

Nat Rev Endocrinol· August 2025

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Inactivation of Thyroid Hormone Transporters Mct8/Oatp1c1 in Mouse Brain Endothelial Cells Causes Region-Specific Alterations in Central Thyroid Hormone Signaling.
Androniki Alevyzaki, Boyka Markova, Meri De Angelis, Timo D Müller, Akila Chandrasekar

Thyroid· July 2025

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Pharmacological weight loss with incretin-based therapies does not result in a disproportionate loss of muscle mass or function in obese mice and humans.
Henning Tim Langer, Natalie K Gilmore, Chris M T Hayden, Julien Roux, Bruno Bariohay

medRxiv· July 2025

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A once-daily GLP-1/GIP/glucagon receptor tri-agonist (NN1706) lowers body weight in rodents, monkeys and humans.
Brian Finan, Jonathan D Douros, Ronald Goldwater, Ann Maria Kruse Hansen, Julie B Hjerpsted

Mol Metab· June 2025

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Estrogenic activity of E2-conjugated GLP-1 is mediated by intracellular endolysosomal acidification and estrone metabolism.
Callum Coupland, Na Sun, Ahmed Khalil, Özüm Ezgi Karaoglu, Arkadiusz Liskiewicz

Mol Metab· June 2025

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GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice.
Robert M Gutgesell, Ahmed Khalil, Arkadiusz Liskiewicz, Gandhari Maity-Kumar, Aaron Novikoff

Nat Metab· June 2025

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Publisher Correction: GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice.
Robert M Gutgesell, Ahmed Khalil, Arkadiusz Liskiewicz, Gandhari Maity-Kumar, Aaron Novikoff

Nat Metab· June 2025

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Calopy - an advanced framework for the integration and analysis of indirect calorimetry data.
Stefan Loipfinger, Matthias Grosholz, Santhosh Kumar, Helin Erbilir, Kenneth Allen Dyar

Nat Metab· June 2025

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Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulation.
Johanna Giuranna, Yiran Zheng, Matthäus Brandt, Sigrid Jall, Amrita Mukherjee

Mol Psychiatry· May 2025

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Glucose-dependent insulinotropic polypeptide (GIP).
Timo D Müller, Alice Adriaenssens, Bo Ahrén, Matthias Blüher, Andreas L Birkenfeld

Mol Metab· May 2025

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[Incretins as the basis of obesity treatment].
Ines Freibothe, Timo Dirk Müller

Inn Med (Heidelb)· May 2025

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Novel pharmacotherapies for weight loss: Understanding the role of incretins to enable weight loss and improved health outcomes.
Thomas Forst, Christophe De Block, Stefano Del Prato, Juan Frias, Anne Lautenbach

Diabetes Obes Metab· April 2025

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Mg Supplementation Mitigates Metabolic Deficits Associated With TRPM7 Disruption.
Severin Boulassel, Pascale C F Schreier, Anna M Melyshi, Johanna Berger, Peter S Reinach

J Cell Physiol· April 2025

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Pantothenate kinase 4 controls skeletal muscle substrate metabolism.
Adriana Miranda-Cervantes, Andreas M Fritzen, Steffen H Raun, Ondřej Hodek, Lisbeth L V Møller

Nat Commun· January 2025

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A "poly-matter network" conception of biological inheritance.
Günter A Müller, Timo D Müller

Genetica· December 2024

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Recent achievements and future directions of anti-obesity medications.
Gerald Grandl, Aaron Novikoff, Xue Liu, Timo D Müller

Lancet Reg Health Eur· December 2024

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Why are we still in need for novel anti-obesity medications?
Aaron Novikoff, Gerald Grandl, Xue Liu, Timo D Müller

Lancet Reg Health Eur· December 2024

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GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells.
Natália da Silva Lima, Alba Cabaleiro, Eva Novoa, Cristina Riobello, Patrick J Knerr

Cell Mol Life Sci· November 2024

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