Publications by authors named "Timo Stellfeld"

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A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition.
Lilia Falkenstern, Victoria Georgi, Stefanie Bunse, Volker Badock, Manfred Husemann, Timo Stellfeld

Sci Rep· January 2024

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Correction to "Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069".
Douglas L Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Timo Stellfeld

J Med Chem· January 2023

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Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists.
Douglas L Orsi, Steven J Ferrara, Stephan Siegel, Anders Friberg, Léa Bouché, Timo Stellfeld

Bioorg Med Chem· January 2023

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Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists and .
Douglas L Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Timo Stellfeld

J Med Chem· November 2022

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Rational Design and Synthesis of Selective PRMT4 Inhibitors: A New Chemotype for Development of Cancer Therapeutics*.
Mathew Sutherland, Alice Li, Anissa Kaghad, Dimitrios Panagopoulos, Fengling Li, Timo Stellfeld

ChemMedChem· April 2021

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Potent and Selective Human Prostaglandin F (FP) Receptor Antagonist (BAY-6672) for the Treatment of Idiopathic Pulmonary Fibrosis (IPF).
Hartmut Beck, Tobias Thaler, Daniel Meibom, Mark Meininghaus, Hannah Jörißen, Timo Stellfeld

J Med Chem· October 2020

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Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2.
Erik Eggert, Roman C Hillig, Silke Koehr, Detlef Stöckigt, Jörg Weiske, Timo Stellfeld

J Med Chem· May 2016

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Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.
Nicolas Reynoird, Pawel K Mazur, Timo Stellfeld, Natasha M Flores, Shane M Lofgren

Genes Dev· April 2016

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Gene expression levels of matrix metalloproteinases in human atherosclerotic plaques and evaluation of radiolabeled inhibitors as imaging agents for plaque vulnerability.
Adrienne Müller, Stefanie D Krämer, Romana Meletta, Katharina Beck, Svetlana V Selivanova, Timo Stellfeld

Nucl Med Biol· August 2014

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Studies toward the development of new silicon-containing building blocks for the direct (18)F-labeling of peptides.
Lukas O Dialer, Svetlana V Selivanova, Carmen J Müller, Adrienne Müller, Timo Stellfeld

J Med Chem· October 2013

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Design, synthesis, and initial evaluation of a high affinity positron emission tomography probe for imaging matrix metalloproteinases 2 and 9.
Svetlana V Selivanova, Timo Stellfeld, Tobias K Heinrich, Adrienne Müller, Stefanie D Krämer

J Med Chem· June 2013

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Single-step radiofluorination of peptides using continuous flow microreactor.
Svetlana V Selivanova, Linjing Mu, Johanna Ungersboeck, Timo Stellfeld, Simon M Ametamey

Org Biomol Chem· May 2012

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18F-labeled bombesin analog for specific and effective targeting of prostate tumors expressing gastrin-releasing peptide receptors.
Michael Honer, Linjing Mu, Timo Stellfeld, Keith Graham, Miljen Martic

J Nucl Med· February 2011

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In vitro and in vivo characterization of novel 18F-labeled bombesin analogues for targeting GRPR-positive tumors.
Linjing Mu, Michael Honer, Jessica Becaud, Miljen Martic, Pius A Schubiger, Timo Stellfeld

Bioconjug Chem· October 2010

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Direct one-step 18F-labeling of peptides via nucleophilic aromatic substitution.
Jessica Becaud, Linjing Mu, Mylène Karramkam, Pius A Schubiger, Simon M Ametamey, Timo Stellfeld

Bioconjug Chem· December 2009

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Synthesis, 18F-labeling, and in vitro and in vivo studies of bombesin peptides modified with silicon-based building blocks.
Aileen Höhne, Linjing Mu, Michael Honer, P August Schubiger, Simon M Ametamey, Timo Stellfeld

Bioconjug Chem· September 2008

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Silicon-based building blocks for one-step 18F-radiolabeling of peptides for PET imaging.
Linjing Mu, Aileen Höhne, P August Schubiger, Simon M Ametamey, Keith Graham, Timo Stellfeld

Angew Chem Int Ed Engl· August 2008

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Tandem intramolecular Michael-aldol reaction as a tool for the construction of the C-ring of hexacyclinic acid.
Andriy Stelmakh, Timo Stellfeld, Markus Kalesse

Org Lett· August 2006

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Asymmetric total synthesis of complex marine natural products.
Jorma Hassfeld, Markus Kalesse, Timo Stellfeld, Mathias Christmann

Adv Biochem Eng Biotechnol· December 2005

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Synthesis of the A,B,C-ring system of hexacyclinic acid.
Timo Stellfeld, Ulhas Bhatt, Markus Kalesse

Org Lett· October 2004

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