Publications by authors named "Timothy A Chan"

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Avelumab induces greater Fc-Fc receptor-dependent natural killer cell activation and dendritic cell crosstalk compared to durvalumab.
Nicole Osborne, Amit Rupani, Vladimir Makarov, Timothy A Chan, Raghvendra M Srivastava

Oncoimmunology· December 2025

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Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference.
Fereshteh Talebi, Fabiana Gregucci, Jalal Ahmed, Nir Ben Chetrit, Brian D Brown, Timothy A Chan, Dhan Chand, Chandan Guha

Oncoimmunology· December 2025

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Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH-Mutant Glioma.
Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Timothy A Chan

Adv Sci (Weinh)· November 2025

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The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs.
Treg Grubb, Pooneh Koochaki, Sayed Matar, Fatme Ghandour, Marc Machaalani, Timothy A Chan

Nat Commun· November 2025

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Development of a recursive partitioning analysis for prediction of radiation necrosis following single-fraction stereotactic radiosurgery for intact brain metastases.
Anirudh Bommireddy, Zachary S Mayo, Chandana A Reddy, Cole Billena, Erik M Davies, Timothy A Chan

J Neurooncol· September 2025

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Single-cell RNA-sequencing of BCG naïve and recurrent non-muscle invasive bladder cancer reveals a CD6/ALCAM-mediated immune-suppressive pathway.
Ivan Juric, Emily E Fink, Hong Qiu, Pierre-Emmanuel Desprez, Arvind Ravi, Timothy A Chan

NPJ Precis Oncol· September 2025

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Inhibition of KDEL receptors remodels the tumor microenvironment for robust T cell independent tumor regression.
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A Chan, William C Merrick

bioRxiv· August 2025

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Distinct Cytokine Patterns Identify Acute and Convalescent Myocardial Involvement After Coronavirus Disease 2019: A Multicohort Biomarker Study.
David A Zidar, Grace A McComsey, Donald D Anthony, John McDaniel, Timothy A Chan

J Infect Dis· June 2025

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Longitudinal and multisite sampling reveals mutational and copy number evolution in tumors during metastatic dissemination.
Karena Zhao, Joris Vos, Stanley Lam, Lillian A Boe, Daniel Muldoon, Timothy A Chan

Nat Genet· June 2025

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Impaired T cell and neoantigen retention in time-serial analysis of metastatic non-small cell lung cancer in patients unresponsive to TIL cell therapy.
Chao Wang, Xiaoqing Yu, Jamie K Teer, Jiqiang Yao, Dongliang Du, Timothy A Chan

Nat Cancer· May 2025

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Author Correction: The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.
Jiacheng He, Xiaolei Chai, Qiansen Zhang, Yang Wang, Yijie Wang, Timothy A Chan

Nat Immunol· April 2025

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Navigating established and emerging biomarkers for immune checkpoint inhibitor therapy.
Stephen L Wang, Timothy A Chan

Cancer Cell· April 2025

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The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.
Jiacheng He, Xiaolei Chai, Qiansen Zhang, Yang Wang, Yijie Wang, Timothy A Chan

Nat Immunol· March 2025

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Practice Patterns and Survival Outcomes of Immunotherapy for Metastatic Colorectal Cancer.
Shahla Bari, Marco Matejcic, Richard D Kim, Hao Xie, Ibrahim H Sahin, Timothy A Chan

JAMA Netw Open· March 2025

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Genomic Landscape of Superficial Malignant Peripheral Nerve Sheath Tumor.
John L McAfee, Tyler J Alban, Vladimir Makarov, Amit Rupani, Prerana B Parthasarathy, Timothy A Chan

Lab Invest· February 2025

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Highly-multiplex detection of plasma cell-free human papillomavirus-16 DNA in oropharyngeal carcinoma.
Payton Clark, Natalya Karasik, Shauna R Campbell, Neil M Woody, Jamie A Ku, Timothy A Chan

J Clin Virol· February 2025

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Single Cell RNA-sequencing of BCG naïve and recurrent non-muscle invasive bladder cancer reveals a CD6/ALCAM-mediated immune-suppressive pathway.
Ivan Juric, Emily E Fink, Hong Qiu, Pierre-Emmanuel Desprez, Arvind Ravi, Timothy A Chan

bioRxiv· February 2025

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Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab.
Tyler J Alban, Nadeem Riaz, Prerana Parthasarathy, Vladimir Makarov, Sviatoslav Kendall, Timothy A Chan

Nat Med· November 2024

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The hallmarks of cancer immune evasion.
Claudia Galassi, Timothy A Chan, Ilio Vitale, Lorenzo Galluzzi

Cancer Cell· November 2024

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Differences in tumor-associated T-cell receptor repertoires between early-onset and average-onset colorectal cancer.
Ya-Yu Tsai, Kanika G Nair, Shimoli V Barot, Shao Xiang, Suneel Kamath, Timothy A Chan

J Natl Cancer Inst· October 2024

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Immunosurveillance in clinical cancer management.
Guido Kroemer, Timothy A Chan, Alexander M M Eggermont, Lorenzo Galluzzi

CA Cancer J Clin· March 2024

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Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer.
Avia D Wilkerson, Prerana Bangalore Parthasarathy, Nickolas Stabellini, Carley Mitchell, Paul G Pavicic, Timothy A Chan

Clin Cancer Res· January 2024

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Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis.
Mytrang H Do, Wei Shi, Liangliang Ji, Erik Ladewig, Xian Zhang, Timothy A Chan

Immunity· November 2023

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Unsupervised and supervised AI on molecular dynamics simulations reveals complex characteristics of HLA-A2-peptide immunogenicity.
Jeffrey K Weber, Joseph A Morrone, Seung-Gu Kang, Leili Zhang, Lijun Lang, Timothy A Chan

Brief Bioinform· November 2023

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Author Correction: 14-3-3σ is required to prevent mitotic catastrophe after DNA damage.
Timothy A Chan, Heiko Hermeking, Christoph Lengauer, Kenneth W Kinzler, Bert Vogelstein

Nature· September 2023

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