Publications by authors named "Timothy A Garrow"

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Hepatic Activity and Transcription of Betaine-Homocysteine Methyltransferase, Methionine Synthase, and Cystathionine Synthase in Periparturient Dairy Cows Are Altered to Different Extents by Supply of Methionine and Choline.
Zheng Zhou, Timothy A Garrow, Xianwen Dong, Daniel N Luchini, Juan J Loor

J Nutr· January 2017

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Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes.
Radhika S Ganu, Yasuko Ishida, Markos Koutmos, Sergios-Orestis Kolokotronis, Alfred L Roca, Timothy A Garrow

PLoS One· May 2016

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Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.
Jana Mládková, Jana Hladílková, Carrie E Diamond, Katherine Tryon, Kazuhiro Yamada, Timothy A Garrow

Proteins· October 2014

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The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase.
Jan Pícha, Václav Vaněk, Miloš Buděšínský, Jana Mládková, Timothy A Garrow

Eur J Med Chem· July 2013

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Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development.
Martin B Lee, Megan Kooistra, Baohua Zhang, Sandy Slow, Amanda L Fortier, Timothy A Garrow

J Biol Chem· September 2012

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Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2.
Jana Mládková, Václav Vaněk, Miloš Buděšínský, Tomáš Elbert, Zuzana Demianová, Timothy A Garrow

J Med Chem· August 2012

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Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas.
Ya-Wen Teng, Mihai G Mehedint, Timothy A Garrow, Steven H Zeisel

J Biol Chem· October 2011

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Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
Jana Strakova, Sapna Gupta, Warren D Kruger, Ryan N Dilger, Katherine Tryon, Timothy A Garrow

Nutr Res· July 2011

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Molecular characterization and analysis of the porcine betaine homocysteine methyltransferase and betaine homocysteine methyltransferase-2 genes.
Radhika S Ganu, Timothy A Garrow, Monika Sodhi, Laurie A Rund, Lawrence B Schook

Gene· March 2011

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Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Jana Strakova, Kelly T Williams, Sapna Gupta, Kevin L Schalinske, Warren D Kruger, Timothy A Garrow

Nutr Res· July 2010

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Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase.
Václav Vanek, Milos Budesínský, Petra Kabeleová, Miloslav Sanda, Milan Kozísek, Timothy A Garrow

J Med Chem· June 2009

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Type I diabetes leads to tissue-specific DNA hypomethylation in male rats.
Kelly T Williams, Timothy A Garrow, Kevin L Schalinske

J Nutr· November 2008

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Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
Sandra S Szegedi, Carmen C Castro, Markos Koutmos, Timothy A Garrow

J Biol Chem· April 2008

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Liver betaine-homocysteine S-methyltransferase activity undergoes a redox switch at the active site zinc.
Carmen Castro, Norman S Millian, Timothy A Garrow

Arch Biochem Biophys· April 2008

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Betaine can partially spare choline in chicks but only when added to diets containing a minimal level of choline.
Ryan N Dilger, Timothy A Garrow, David H Baker

J Nutr· October 2007

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Osmotic regulation of betaine homocysteine-S-methyltransferase expression in H4IIE rat hepatoma cells.
Christine Schäfer, Lars Hoffmann, Katrin Heldt, Mohammad Reza Lornejad-Schäfer, Gernot Brauers, Timothy A Garrow

Am J Physiol Gastrointest Liver Physiol· April 2007

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Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats.
Kristin M Nieman, Cara S Hartz, Sandra S Szegedi, Timothy A Garrow, Janet D Sparks

Am J Physiol Endocrinol Metab· December 2006

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Liver choline dehydrogenase and kidney betaine-homocysteine methyltransferase expression are not affected by methionine or choline intake in growing rats.
Sandy Slow, Timothy A Garrow

J Nutr· September 2006

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Inhibition of betaine-homocysteine S-methyltransferase causes hyperhomocysteinemia in mice.
Michaela Collinsova, Jana Strakova, Jiri Jiracek, Timothy A Garrow

J Nutr· June 2006

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S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase.
Jiri Jiracek, Michaela Collinsova, Ivan Rosenberg, Milos Budesinsky, Eva Protivinska, Timothy A Garrow

J Med Chem· June 2006

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Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver.
Shobhitha Ratnam, Enoka P Wijekoon, Beatrice Hall, Timothy A Garrow, Margaret E Brosnan

Am J Physiol Endocrinol Metab· May 2006

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Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro.
Catherine M Miller, Sandra S Szegedi, Timothy A Garrow

Biochem J· December 2005

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Dietary S-methylmethionine, a component of foods, has choline-sparing activity in chickens.
Nathan R Augspurger, Colleen S Scherer, Timothy A Garrow, David H Baker

J Nutr· July 2005

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High sodium chloride intake decreases betaine-homocysteine S-methyltransferase expression in guinea pig liver and kidney.
Cassandra V Delgado-Reyes, Timothy A Garrow

Am J Physiol Regul Integr Comp Physiol· January 2005

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Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid.
Kristin M Nieman, Matthew J Rowling, Timothy A Garrow, Kevin L Schalinske

J Biol Chem· October 2004

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